Protein Aggregation, Pathological [patologická konformace proteinů]

topical
16
Terms

patologická agregace bílkovin

Persistent link   https://www.medvik.cz/link/D066263
Definition

A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

DUI
D066263 MeSH Browser
CUI
M0593510
History note
2015
Public note
2015

Allowable subheadings

BL
blood
CF
cerebrospinal fluid
CI
chemically induced 1
CL
classification 1
CO
complications
CN
congenital
DI
diagnosis
DG
diagnostic imaging
DH
diet therapy
DT
drug therapy 2
EC
economics
EM
embryology
EN
enzymology
EP
epidemiology
EH
ethnology
ET
etiology
GE
genetics 2
HI
history
IM
immunology
ME
metabolism 7
MI
microbiology
MO
mortality
NU
nursing
PS
parasitology 1
PA
pathology 3
PP
physiopathology 1
PC
prevention & control 1
PX
psychology
RT
radiotherapy
RH
rehabilitation
SU
surgery
TH
therapy
UR
urine
VE
veterinary
VI
virology

C Diseases
C23 Pathological Conditions, Signs and Symptoms 451
C23.550 Pathologic Processes 195
C23.550.035 Acantholysis 10
C23.550.073 Arrhythmias, Cardiac 2 797
C23.550.081 Ascites 335
C23.550.113 Atrial Remodeling 13
C23.550.145 Azotemia 5
C23.550.161 Cardiotoxicity 142
C23.550.177 Channelopathies 14
C23.550.210 Chromosome Aberrations 1 578
C23.550.260 Death 1 400
C23.550.274 Dehydration 403
C23.550.277 Delayed Graft Function 25
C23.550.288 Disease 1 712
C23.550.291 Disease Attributes 1 208
C23.550.308 Dysbiosis 107
C23.550.325 Emphysema 89
C23.550.340 Extravasation of Diagnostic and Therapeutic Materials 36
C23.550.347 Femoracetabular Impingement 27
C23.550.355 Fibrosis 366
C23.550.359 Frailty 122
C23.550.362 Genomic Instability 88
C23.550.369 Gliosis 37
C23.550.382 Granuloma 236
C23.550.384 Granulomatosis, Orofacial 6
C23.550.393 Growth Disorders 636
C23.550.403 Hemolysis 384
C23.550.414 Hemorrhage 2 296
C23.550.421 Hyperammonemia 31
C23.550.425 Hyperamylasemia 5
C23.550.429 Hyperbilirubinemia 184
C23.550.444 Hyperplasia 340
C23.550.449 Hyperuricemia 225
C23.550.455 Hypovolemia 87
C23.550.470 Inflammation 3 480
C23.550.505 Intraoperative Complications 717
C23.550.513 Ischemia 1 731
C23.550.522 Leukoaraiosis 4
C23.550.526 Leukocytosis 98
C23.550.537 Lithiasis 87
C23.550.543 Long Term Adverse Effects 7
C23.550.548 Malacoplakia 4
C23.550.568 Menstruation Disturbances 353
C23.550.589 Metaplasia 98
C23.550.695 Muscle Weakness 225
C23.550.706 Myotoxicity 1
C23.550.717 Necrosis 837
C23.550.722 Neointima 8
C23.550.727 Neoplastic Processes 130
C23.550.737 Nerve Degeneration 166
C23.550.744 Ochronosis 42
C23.550.751 Ossification, Heterotopic 139
C23.550.753 Ototoxicity 10
C23.550.755 Pigmentation Disorders 132
C23.550.759 Polydipsia 17
C23.550.767 Postoperative Complications 7 077
C23.550.770 Protein Aggregation, Pathological 16
C23.550.773 Respiratory Aspiration 79
C23.550.794 Retropneumoperitoneum 14
C23.550.823 Sclerosis 84
C23.550.835 Shock 410
C23.550.863 Teratogenesis 27
C23.550.877 Toxic Optic Neuropathy 1
C23.550.891 Ulcer 201
C23.550.918 Vascular Remodeling 29
C23.550.945 Yang Deficiency 9
C23.550.972 Yin Deficiency 9

G Phenomena and Processes
G02 Chemical Phenomena 308
G02.111 Biochemical Phenomena 370
G02.111.007 Acid-Base Equilibrium 445
G02.111.012 Acylation 24
G02.111.017 Aerobiosis 73
G02.111.026 Agglutination 53
G02.111.035 Alkylation 65
G02.111.044 Allosteric Regulation 70
G02.111.053 Amination 7
G02.111.062 Anaerobiosis 143
G02.111.071 Autotrophic Processes 13
G02.111.080 Base Composition 127
G02.111.084 Binding, Competitive 61
G02.111.086 Biocatalysis 83
G02.111.087 Biochemical Processes obsolete
G02.111.092 Biomineralization 4
G02.111.098 Biosynthetic Pathways 50
G02.111.109 Biotinylation 20
G02.111.130 Body Composition 535
G02.111.150 Brain Chemistry 423
G02.111.158 Carbohydrate Metabolism 492
G02.111.165 Citric Acid Cycle 57
G02.111.180 Cyclization 55
G02.111.188 Dealkylation 4
G02.111.192 Deamination 10
G02.111.195 Decarboxylation 17
G02.111.210 DNA Cleavage 15
G02.111.218 DNA Methylation 444
G02.111.222 DNA Repair 472
G02.111.225 DNA Replication 289
G02.111.240 Down-Regulation 300
G02.111.248 Electron Transport 160
G02.111.255 Energy Transfer 322
G02.111.263 Enzyme Activation 380
G02.111.270 Esterification 62
G02.111.323 Halogenation 45
G02.111.375 Heterotrophic Processes 20
G02.111.380 Hydrogenation 24
G02.111.385 Hydroxylation 65
G02.111.490 Kinetics 1 103
G02.111.515 Lipid Peroxidation 759
G02.111.528 Lipogenesis 58
G02.111.534 Lipolysis 181
G02.111.540 Lipoylation 11
G02.111.545 Melanogenesis
G02.111.550 Membrane Fluidity 83
G02.111.560 Molecular Mimicry 38
G02.111.570 Molecular Structure 1 332
G02.111.587 Nitrogen Cycle 6
G02.111.595 Nitrosation 12
G02.111.603 Nucleic Acid Denaturation 62
G02.111.611 Nucleic Acid Hybridization 172
G02.111.619 Nucleic Acid Renaturation 2
G02.111.635 Osmoregulation 11
G02.111.655 Osmosis 77
G02.111.660 Peptide Biosynthesis 43
G02.111.665 Phosphorylation 720
G02.111.669 Phototrophic Processes 25
G02.111.672 Prenylation 14
G02.111.675 Protein Aggregation, Pathological 16
G02.111.679 Protein Binding 1 253
G02.111.688 Protein Folding 107
G02.111.691 Protein Modification, Translational 7
G02.111.694 Protein Multimerization 123
G02.111.700 Protein Stability 94
G02.111.720 Proteolysis 130
G02.111.730 Proteostasis 5
G02.111.740 RNA Cleavage 6
G02.111.750 RNA Folding 5
G02.111.760 RNA Processing, Post-Transcriptional 57
G02.111.770 RNA Replication
G02.111.780 RNA Stability 46
G02.111.810 Sequence Homology 74
G02.111.820 Signal Transduction 2 210
G02.111.830 Structure-Activity Relationship 1 820
G02.111.833 Substrate Cycling 1
G02.111.835 Substrate Specificity 335
G02.111.873 Transcription, Genetic 658
G02.111.905 Up-Regulation 376

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