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Pracoviště: Epilepsiezentrum Kork Germany

1 záznamů v Medvik Filtry

Článek

European trends in epilepsy surgery

Baud, Maxime O
Autor Baud, Maxime O From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Perneger, Thomas
Autor Perneger, Thomas From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Rácz, Attila
Autor Rácz, Attila From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Pensel, Max C
Autor Pensel, Max C From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Elger, Christian
Autor Elger, Christian From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Rydenhag, Bertil
Autor Rydenhag, Bertil From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Malmgren, Kristina
Autor Malmgren, Kristina From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Cross, J Helen
Autor Cross, J Helen From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
McKenna, Grainne
Autor McKenna, Grainne From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania
Tisdall, Martin
Autor Tisdall, Martin From the Department of Neurology (M.O.B., S.V., F.P., M.S.), and Center for Clinical Research (T.P.), University Hospital Geneva Department of Neurology (M.O.B.), University Hospital Bern Wyss Center for Bio- and Neuro-Engineering (M.O.B.), Geneva, Switzerland Klinik und Poliklinik für Epileptologie (A.R., M.C.P., C.E.), Universitätsklinikum Bonn, Germany Sahlgrenska University Hospital and Sahlgrenska Academy at the University of Gothenburg (B.R., K. Malmgren), Sweden UCL Great Ormond Street Hospital (J.H.C., G.M., M.T.), London, UK Department of Child Neurology (H.J.L., K.P.J.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands Department of Functional Neurology and Epileptology (S. Rheims, J.I., P.R., F.M.) and Department of Clinical Epileptology, Sleep Disorders, and Functional Neurology in Children (A.A., P.R.), Hospices Civils de Lyon and University of Lyon, France Department of Neurology (P.R.), University Hospital Lausanne, Switzerland Department of Neurology (S.A., K.D., C.O.), Cerrahpasa Medical Faculty, Istanbul University, Turkey Clinic for Neuroscience (M.L.), National Center for Epilepsy, Oslo University Hospital, Norway Epilepsy Centre, (I.R.), Masaryk University, Hospital Ste Anne, and CEITEC-Neuroscience Centre, Brno, Czech Republic Kuopio University Hospital and University of Eastern Finland (R.K., L.-M.V.) St. Ivan Rilski University Hospital (P.D., K. Minkin), Bulgaria Epilepsiezentrum Kork (A.M.S., B.J.S.), Germany Second Faculty of Medicine (A.K., P.K.,, P.M.), Charles University, Motol University Hospital, Prague, Czech Republic Juhász Pál Epilepsy Centrum (Z.J., D.F.), National Institute of Clinical Neurosciences, Hungary Reference Center for Refractory Epilepsy (E.C., P.B.), Ghent University Hospital, Belgium and Department of Neurology and Neurosurgery (S. Rocka, R.M.), Vilnius University, Lithuania

Neurology. 2018 ; 91 (2) : e96-e106. [pub] 20180613

ISSN 1526-632X
Medvik
Zdroj

OBJECTIVE: Resective surgery is effective in treating drug-resistant focal epilepsy, but it remains unclear whether improved diagnostics influence postsurgical outcomes. Here, we compared practice and outcomes over 2 periods 15 years apart. METHODS: Sixteen European centers retrospectively identified 2 cohorts of children and adults who underwent epilepsy surgery in the period of 1997 to 1998 (n = 562) or 2012 to 2013 (n = 736). Data collected included patient (sex, age) and disease (duration, localization and diagnosis) characteristics, type of surgery, histopathology, Engel postsurgical outcome, and complications, as well as imaging and electrophysiologic tests performed for each case. Postsurgical outcome predictors were included in a multivariate logistic regression to assess the strength of date of surgery as an independent predictor. RESULTS: Over time, the number of operated cases per center increased from a median of 31 to 50 per 2-year period (p = 0.02). Mean disease duration at surgery decreased by 5.2 years (p < 0.001). Overall seizure freedom (Engel class 1) increased from 66.7% to 70.9% (adjusted p = 0.04), despite an increase in complex surgeries (extratemporal and/or MRI negative). Surgeries performed during the later period were 1.34 times (adjusted odds ratio; 95% confidence interval 1.02-1.77) more likely to yield a favorable outcome (Engel class I) than earlier surgeries, and improvement was more marked in extratemporal and MRI-negative temporal epilepsy. The rate of persistent neurologic complications remained stable (4.6%-5.3%, p = 0.7). CONCLUSION: Improvements in European epilepsy surgery over time are modest but significant, including higher surgical volume, shorter disease duration, and improved postsurgical seizure outcomes. Early referral for evaluation is required to continue on this encouraging trend.

MeSH
časové faktory MeSH
dítě MeSH
dospělí MeSH
elektrofyziologické jevy MeSH
kojenec MeSH
lidé středního věku MeSH
lidé MeSH
mladiství MeSH
mladý dospělý MeSH
neurochirurgické výkony statistika a číselné údaje MeSH
neurozobrazování MeSH
pooperační komplikace epidemiologie MeSH
předškolní dítě MeSH
refrakterní epilepsie epidemiologie chirurgie MeSH
retrospektivní studie MeSH
výsledek terapie * MeSH
Check Tag
dítě MeSH
dospělí MeSH
kojenec MeSH
lidé středního věku MeSH
lidé MeSH
mladiství MeSH
mladý dospělý MeSH
mužské pohlaví MeSH
předškolní dítě MeSH
ženské pohlaví MeSH
Publikační typ
časopisecké články MeSH
multicentrická studie MeSH
práce podpořená grantem MeSH
srovnávací studie MeSH
Geografické názvy
Evropa MeSH

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