Enhancement of the immune response leading to protection against bacterial and fungal infections was shown using different schedules of immunization with microbial pigments and a polysaccharide. The group of mice given carotenoids of Rhodotorula glutinis (preparation I) and polysaccharide of Spitulina platensis (IV) survived for 2 weeks after Pseudomonas aeruginosa infection. The groups of mice given carotenoids (I), polysaccharide (IV), I+IV and with the crude phycocyanin of S. platensis (III)+IV survived for 2 weeks after Candida albicans infection. All other groups recorded a maximum level of mortality reaching 2 mice per group either after immunization or post-infection. Adding the carotenoids, phycocyanin and polysaccharides to food as additives might therefore enhance the human immune response against microbial infections.

• MeSH
• analýza přežití MeSH
• Candida albicans imunologie   MeSH
• časové faktory MeSH
• imunologické faktory aplikace a dávkování   izolace a purifikace   MeSH
• kandidóza imunologie   prevence a kontrola   MeSH
• karotenoidy farmakologie   izolace a purifikace   MeSH
• myši MeSH
• pseudomonádové infekce imunologie   prevence a kontrola   MeSH
• Pseudomonas aeruginosa imunologie   MeSH
• Rhodotorula chemie   MeSH
• Spirulina chemie   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• myši MeSH
• ženské pohlaví MeSH
• zvířata MeSH