-
Autor
Asakai, Hiroko 1 Asaki, S Yukiko 1 Balaji, Seshadri 1 Bradley, David J 1 Bulic, Anica 1 Chubb, Henry 1 Czosek, Richard J 1 Dubin, Anne M 1 Escudero, Carolina 1 Fischbach, Peter 1 Fumanelli, Jennifer 1 Hill, Allison C 1 Horndasch, Michaela 1 Janousek, Jan 1 Kwok, Sit Yee 1 Mah, Douglas 1 Malloy-Walton, Lindsey 1 Mangat, Jasveer 1 McElhinney, Doff B 1 Moore, Jeremy P 1
-
Pracoviště
Cardiology Centre Department of Paedi... 1 Children's Heart Centre 2nd Faculty o... 1 Children's Mercy Hospital University ... 1 Department of Cardiology Boston Child... 1 Department of Congenital Heart Diseas... 1 Department of Paediatrics University ... 1 Department of Pediatric Cardiology Ge... 1 Department of Pediatrics Division of ... 1 Department of Pediatrics Division of ... 1 Department of Pediatrics Harvard Medi... 1 Division of Cardiology Children's Hos... 1 Division of Cardiology Department of ... 1 Division of Cardiology Department of ... 1 Division of Pediatric Cardiology Depa... 1 Division of Pediatric Cardiology Depa... 1 Division of Pediatric Cardiothoracic ... 1 Joe DiMaggio Children's Hospital Holl... 1 Keck School of Medicine University of... 1 Labatt Family Heart Centre The Hospit... 1 Paediatric Cardiology Evelina London ... 1
- Formát
- Publikační typ
- Check Tag
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Dostupnost
- Vlastník
-
Autor
Asakai, Hiroko 1 Asaki, S Yukiko 1 Balaji, Seshadri 1 Bradley, David J 1 Bulic, Anica 1 Chubb, Henry 1 Czosek, Richard J 1 Dubin, Anne M 1 Escudero, Carolina 1 Fischbach, Peter 1 Fumanelli, Jennifer 1 Hill, Allison C 1 Horndasch, Michaela 1 Janousek, Jan 1 Kwok, Sit Yee 1 Mah, Douglas 1 Malloy-Walton, Lindsey 1 Mangat, Jasveer 1 McElhinney, Doff B 1 Moore, Jeremy P 1
-
Pracoviště
Cardiology Centre Department of Paedi... 1 Children's Heart Centre 2nd Faculty o... 1 Children's Mercy Hospital University ... 1 Department of Cardiology Boston Child... 1 Department of Congenital Heart Diseas... 1 Department of Paediatrics University ... 1 Department of Pediatric Cardiology Ge... 1 Department of Pediatrics Division of ... 1 Department of Pediatrics Division of ... 1 Department of Pediatrics Harvard Medi... 1 Division of Cardiology Children's Hos... 1 Division of Cardiology Department of ... 1 Division of Cardiology Department of ... 1 Division of Pediatric Cardiology Depa... 1 Division of Pediatric Cardiology Depa... 1 Division of Pediatric Cardiothoracic ... 1 Joe DiMaggio Children's Hospital Holl... 1 Keck School of Medicine University of... 1 Labatt Family Heart Centre The Hospit... 1 Paediatric Cardiology Evelina London ... 1
- Formát
- Publikační typ
- Check Tag
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Dostupnost
- Vlastník
Asaki, S Yukiko* Dotaz Zobrazit nápovědu
- Chubb, Henry
- Bulic, Anica
- Mah, Douglas
-
Moore, Jeremy P
Autor Moore, Jeremy P Division of Cardiology, Department of Pediatrics, UCLA Health System, Los Angeles, California, USA Division of Cardiology, Department of Medicine, Ahmanson/UCLA Adult Congenital Heart Disease Center, Los Angeles, California, USA UCLA Cardiac Arrhythmia Center, UCLA Health System, Los Angeles, California, USA
- Janousek, Jan
- Fumanelli, Jennifer
- Asaki, S Yukiko
- Pflaumer, Andreas
- Hill, Allison C
- Escudero, Carolina
Open Access Digital Library od 1998-01-01
Elsevier Open Archive Journals od 1983-01-01 do Před 1 rokem
PubMed
36007989
DOI
10.1016/j.jacc.2022.05.053
Knihovny.cz E-zdroje
BACKGROUND: Palliation of the single ventricle (SV) circulation is associated with a burden of lifelong complications. Previous studies have identified that the need for a permanent ventricular pacing system (PPMv) may be associated with additional adverse long-term outcomes. OBJECTIVES: The goal of this study was to quantify the attributable risk of PPMv in patients with SV, and to identify modifiable risk factors. METHODS: This international study was sponsored by the Pediatric and Congenital Electrophysiology Society. Centers contributed baseline and longitudinal data for functionally SV patients with PPMv. Enrollment was at implantation. Controls were matched 1:1 to PPMv subjects by ventricular morphology and sex, identified within center, and enrolled at matched age. Primary outcome was transplantation or death. RESULTS: In total, 236 PPMv subjects and 213 matched controls were identified (22 centers, 9 countries). Median age at enrollment was 5.3 years (quartiles: 1.5-13.2 years), follow-up 6.9 years (3.4-11.6 years). Median percent ventricular pacing (Vp) was 90.8% (25th-75th percentile: 4.3%-100%) in the PPMv cohort. Across 213 matched pairs, multivariable HR for death/transplant associated with PPMv was 3.8 (95% CI 1.9-7.6; P < 0.001). Within the PPMv population, higher Vp (HR: 1.009 per %; P = 0.009), higher QRS z-score (HR: 1.19; P = 0.009) and nonapical lead position (HR: 2.17; P = 0.042) were all associated with death/transplantation. CONCLUSIONS: PPMv in patients with SV is associated with increased risk of heart transplantation and death, despite controlling for increased associated morbidity of the PPMv cohort. Increased Vp, higher QRS z-score, and nonapical ventricular lead position are all associated with higher risk of adverse outcome and may be modifiable risk factors.
Sdílet
Název dokumentu
Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.