Práce přináší stručný přehled současných informací a doporučení pro operační léčbu karcinomu prsu v těhotenství vč. tří aktuálně problémových oblastí – indikace prs šetřícího výkonu v 1. trimestru těhotenství, indikace biopsie sentinelové uzliny a její techniku a monitorování plodu v průběhu operace.
This paper provides a brief overview of current information and recommendations for surgical treatment of breast cancer in pregnancy, including three currently controversial areas – indications for breast-conserving surgery in the 1st trimester of pregnancy, indications for sentinel lymph node biopsy and its technique, and fetal monitoring during surgery.
- MeSH
- laktace MeSH
- lidé MeSH
- nádorové komplikace v těhotenství * chirurgie MeSH
- nádory prsu * chirurgie MeSH
- perioperační péče MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- komplikace těhotenství MeSH
- kostní denzita MeSH
- laktace MeSH
- lidé MeSH
- nealkoholová steatóza jater farmakoterapie MeSH
- osteoporóza * farmakoterapie MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- Publikační typ
- souhrny MeSH
Bonding je charakterizovaný ako vzťah, ktorý upevňuje citovú väzbu medzi matkou a novorodencom, podporuje adaptáciu, termoreguláciu a imunitu novorodenca.
Bonding is characterized as a relationship that strengthens the emotional bond between mother and newborn, promotes adaptation, thermoregulation and immunity of the newborn. The aim of the study was to conduct a systematic collection and quantitative analysis of bonding data. To determine whether there is a statistically significant relationship between bonding and full breastfeeding of newborns at discharge to home care. We used document content analysis method (n = 1 650) and correlation analysis method to collect data. In the set of newborns born in 2023, we identified the implementation of bonding in 1 282 newborns (77,7 %). At discharge to home care, 65,3 % of newborns were fully breastfed (n = 1 078). The results of the analysis confirmed statistical significance between bonding and full breastfeeding of newborns (r = 0.9178).
- Klíčová slova
- bonding,
- MeSH
- kojení psychologie MeSH
- laktace MeSH
- lidé MeSH
- novorozenec MeSH
- připoutání k objektu MeSH
- vztahy mezi matkou a dítětem * MeSH
- Check Tag
- lidé MeSH
- novorozenec MeSH
- ženské pohlaví MeSH
Goals: This study aims to identify sociodemographic predictors of breastfeeding and evaluate the effect of nursing interventions on nutritional strategies in premature infants (0-6 months). Methods: A prospective monocentric longitudinal study focused on the nutritional management of 201 preterm infants. Monitoring was performed for two years at specific time intervals. Results: The mother's nationality influences the child's nutrition in the first weeks but this influence decreases with the child's age. The mother's education has a significant effect on nutritional choices. Higher education correlates with using different nutritional combinations. Strong predictors of breastfeeding include the first latch, skin-to-skin contact, and orofacial stimulation. Conclusion: The study identified vital factors influencing the nutrition of preterm infants. These findings enable better targeting of measures and support better health and development of such children. The results provide a scientific basis for the development of nutritional strategies and interventions.
Terapie v těhotenství a laktaci má u pacientek s revmatoidní artritidou svá specifická úskalí. Vysoká aktivita revmatoidní artritidy v průběhu těhotenství přináší rizika nejen pro matku, ale i pro dítě (ztráta plodu, předčasný porod, nízká porodní hmotnost a další). Léčba revmatoidní artritidy se opírá o celou řadu léků od nesteroidních antirevmatik, glukokortikoidů, konvenčních chorobu modifikujících léků, biologik až po cílené syntetické léky. Podávání celé řady těchto léčiv je v těhotenství a laktaci, bud' úplně kontraindikováno, nebo je výrazně omezeno. Certolizumab pegol byl prvním biologickým lékem, který se etabloval v terapii obtížně kontrolovatelné revmatoidní artritidy v těhotenství.
Therapy during pregnancy and lactation presents specific challenges for patients with rheumatoid arthritis. High activity of rheumatoid arthritis during pregnancy poses risks to both the mother and the child, including fetal loss, premature birth, and low birth weight. Treatment of rheumatoid arthritis relies on a range of drugs including non-steroidal antirheumatic drugs, glucocorticoids, conventional disease-modifying drugs, biologics, and targeted synthetic drugs. Administering many of these drugs is either completely contraindicated or significantly restricted during pregnancy and lactation. Certolizumab pegol has been the first biologic drug to establish itself in treating challenging cases of rheumatoid arthritis during pregnancy.
- Klíčová slova
- Cetrolizumab pegol, studie CRADLE, studie CRIB,
- MeSH
- biologická terapie metody MeSH
- dospělí MeSH
- klinické zkoušky jako téma MeSH
- laktace účinky léků MeSH
- lidé MeSH
- revmatoidní artritida * farmakoterapie imunologie komplikace MeSH
- těhotenství * imunologie účinky léků MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- těhotenství * imunologie účinky léků MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
Kojící ženy často provází pocit nedostatku mateřského mléka, který však nemusí odpovídat objektivní skutečnosti. Jedním z tradičně doporučovaných prostředků k navýšení tvorby mateřského mléka jsou bylinné kapsle obsahující pískavici řecké seno, samotnou nebo v kombinaci s dalšími bylinami. Otázkou je, zda užívání těchto bylin skutečně může kojení nějak ovlivnit a zda zároveň nemůže mít nějaké negativní dopady na matku nebo její kojené dítě.
Lactating women are often accompanied by a feeling of lack of breast milk, but this may not correspond to objective reality. One of the traditionally recommended means to increase the production of breast milk are herbal capsules containing fenugreek, alone or in combination with other herbs. The question is whether the use of these herbs can really affect breastfeeding and whether it does not have any negative effects on the mother or her nursing baby.
The circadian clock is one of the most important homeostatic systems regulating the majority of physiological functions. Its proper development contributes significantly to the maintenance of health in adulthood. Methadone is recommended for the treatment of opioid use disorders during pregnancy, increasing the number of children prenatally exposed to long-acting opioids. Although early-life opioid exposure has been studied for a number of behavioral and physiological changes observed later in life, information on the relationship between the effects of methadone exposure and circadian system development is lacking. Using a rat model, we investigated the effects of prenatal and early postnatal methadone administration on the maturation of the circadian clockwork in the suprachiasmatic nucleus (SCN) and liver, the rhythm of aralkylamine N-acetyltransferase (AA-NAT) activity in the pineal gland, and gene expression in the livers of 20-day-old rats. Our data show that repeated administration of methadone to pregnant and lactating mothers has significant effect on rhythmic gene expression in the SCN and livers and on the rhythm of AA-NAT in the offspring. Similar to previous studies with morphine, the rhythm amplitudes of the clock genes in the SCN and liver were unchanged or enhanced. However, six of seven specific genes in the liver showed significant downregulation of their expression, compared to the controls in at least one experimental group. Importantly, the amplitude of the AA-NAT rhythm was significantly reduced in all methadone-treated groups. As there is a strong correlation with melatonin levels, this result could be of importance for clinical practice.
- MeSH
- cirkadiánní rytmus fyziologie MeSH
- epifýza mozková * metabolismus MeSH
- krysa rodu rattus MeSH
- laktace MeSH
- melatonin * farmakologie MeSH
- methadon metabolismus farmakologie MeSH
- nucleus suprachiasmaticus fyziologie MeSH
- těhotenství MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Dosažení plného kojení nezralého novorozence je výzvou pro zdravotníky i pro matky, které porodily předčasně. K naplnění tohoto cíle je nutné udržet laktaci matky často i několik týdnů, než budou zahájeny první pokusy o kojení. Do doby, než bude dítě schopné koordinovat sání, dýchání a polykání, je možné implementovat do péče o nezralého novorozence mnoho intervencí, které mohou následné kojení usnadnit. Jde především o kontakt skin to skin, orální motorické intervence a alternativní metody krmení. Opomíjená by neměla zůstat podpora emoční stability ženy a podpora kojení i po propuštění dítěte do domácí péče.
Achieving full breastfeeding of a premature newborn is a challenge for health professionals as well as for mothers who have given birth prematurely. To achieve this goal, it is necessary to maintain the mother's lactation, often for several weeks, before the first attempts at breastfeeding are initiated. Until the baby is able to coordinate sucking, breathing, and swallowing, it is possible to implement many interventions in the care of the premature new-born that can facilitate subsequent breastfeeding. It is mainly the skin-to-skin contact, oral motor interventions, and alternative feeding methods. Support for a woman's emotional stability and support for breastfeeding should not be neglected even after the child is released to home care.
OBJECTIVES: The good healing of the hysterotomy after cesarean section is important for subsequent pregnancies. However, the factors which improve this healing have not been completely described, yet. In this study, we focused on factors which may affect healing of hysterotomy within one year after delivery, such as menstruation, breastfeeding, and the use of the contraception. MATERIAL AND METHODS: Following delivery, total of 540 women were invited for three consecutive visits at six weeks, six months, and 12 months postpartum. The presence of menstruation, frequency of breastfeeding and contraception use were recorded. The scar was evaluated by vaginal ultrasound as already described. The impact of menstruation, breastfeeding, and contraception method on presence of niche was evaluated. RESULTS: The presence of menstruation increased odds to have niche by 45% (CI 1.046-2.018, p = 0.026). Secondarily, our results demonstrated a statistically significant protective effect of breastfeeding on the incidence of niche with OR 0.703 (CI 0.517-0.955, p = 0.024). Breastfeeding decreases odds to have niche by 30%. Also, the use of gestagen contraception lowered the odds by 40% and intrauterine device (IUD) or combine oral contraceptive (COC) by 46.5%. The other possibly intervening factors were statistically controlled. CONCLUSIONS: Amenorrhea, breast-feeding and progesterone-contraceptive decreases the risk of uterine niche within one year follow up.
- MeSH
- amenorea * MeSH
- antikoncepce metody MeSH
- císařský řez MeSH
- hysterotomie MeSH
- laktace * MeSH
- lidé MeSH
- ochranné faktory MeSH
- poporodní období MeSH
- retrospektivní studie MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
