In the context of the COVID-19 pandemic, across six correlational studies in four different countries (total N = 4937), we examined the link between citizens' anger with and admiration for the government's actions and decisions (i.e., system-based anger and admiration) and engagement in preventive behaviour. The internal meta-analyses showed that individuals who admired the government's actions were more likely to adopt personal hygiene and social distancing behaviour. Yet, the link between emotions and preventive behaviour differed concerning the target of emotions, especially for anger. Specifically, anger about restrictions imposed by the government was negatively related to preventive behaviours, but this relationship was not significant when the target of anger was the government's overall handling of the pandemic. Our findings emphasise the importance of citizens' emotions and the targets of those emotions during the crisis.

• Klíčová slova
• Crisis, Emotion's targets, Personal hygiene, Restrictions, Social distancing,
• MeSH
• COVID-19 * MeSH
• lidé MeSH
• pandemie MeSH
• vláda MeSH
• zlost MeSH
• zpráva o sobě MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, complex skin disease, we performed a meta-analysis of >15 million genetic variants in 21,399 cases and 95,464 controls from populations of European, African, Japanese and Latino ancestry, followed by replication in 32,059 cases and 228,628 controls from 18 studies. We identified ten new risk loci, bringing the total number of known atopic dermatitis risk loci to 31 (with new secondary signals at four of these loci). Notably, the new loci include candidate genes with roles in the regulation of innate host defenses and T cell function, underscoring the important contribution of (auto)immune mechanisms to atopic dermatitis pathogenesis.

• MeSH
• atopická dermatitida etnologie   genetika   patologie   MeSH
• celogenomová asociační studie * MeSH
• etnicita genetika   MeSH
• genetická predispozice k nemoci * MeSH
• genetické lokusy * MeSH
• genetické markery genetika   MeSH
• jednonukleotidový polymorfismus genetika   MeSH
• lidé MeSH
• přirozená imunita genetika   MeSH
• rizikové faktory MeSH
• studie případů a kontrol MeSH
• T-lymfocyty cytologie   imunologie   metabolismus   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• genetické markery MeSH