Chronic and recurrent abdominal pain are frequent diagnostic problems in school age and adolescent children. The authors examined the IgG antibodies to Helicobacter pylori using ELISA in a group of 91 children. Positive results were found in 20 children, i.e. 22%. All children positive for Helicobacter pylori antibodies underwent an endoscopic examination with bioptic sampling of the gastric and duodenal mucosa. Bioptic samples were examined histologically and Helicobacter pylori was identified microscopically and using urease tests and cultivation. All 20 children with antibodies to Helicobacter pylori had histological evidence of chronic gastritis in the gastric antrum and infection with Helicobacter pylori was found in 16 cases. Detection of Helicobacter pylori IgG antibodies is useful in the selection of patients for endoscopic examination of the stomach and duodenum. Endoscopy is relevant also where antibodies to Helicobacter pylori are negative and the characteristic picture of chronic disease of the upper gastrointestinal tract is present.
- MeSH
- bolesti břicha etiologie MeSH
- chronická nemoc MeSH
- dítě MeSH
- ELISA MeSH
- gastrointestinální nemoci komplikace diagnóza mikrobiologie MeSH
- Helicobacter pylori * imunologie MeSH
- infekce vyvolané Helicobacter pylori komplikace diagnóza MeSH
- lidé MeSH
- mladiství MeSH
- protilátky bakteriální MeSH
- recidiva MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- protilátky bakteriální MeSH
In the period from 1990 to 1992 542 children aged 0-15 years were examined by the breath hydrogen test for abdominal pain and chronic nutritional disorder. The results of lactose tests were pathological in 107 children with abdominal pain and 95 with chronic nutritional disorder. The authors followed 107 children with abdominal pain and directed their attention to its relationship to lactose intolerance. It was confirmed to be the only cause of abdominal pain in twenty-six children (24.3%). In spite of the well known pathogenetic mechanism of lactose intolerance leading to abdominal pain and metheorism and loose stools, an atypical clinical course was observed in these patients. There were no complaints associated with the intake of milk in history, the abdominal pain being the leading symptom in all patients but four who had loose stools. There was an improvement of clinical symptoms after the low-lactose diet.
- MeSH
- bolesti břicha etiologie MeSH
- diferenciální diagnóza MeSH
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- nesnášenlivost laktózy komplikace diagnóza terapie MeSH
- předškolní dítě MeSH
- Check Tag
- dítě MeSH
- kojenec MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
Elevated alpha-amylase activity in serum was thought for a long time to be a laboratory standard in diagnosis of acute pancreatic disease. The purpose of this study was to evaluate the clinical usefulness of routine measurement of total serum amylase (using the Boehringer Mannheim EPS method) and pancreatic isoamylase (using Boehringer Mannheim EPS method) and lipase (Kodak Eastman) in children. Authors examined the group of 93 children with abdominal pain whose age ranged from 5 to 17 years. In previous laboratory measurements using Spofa test (Slovakofarma) they were found to have elevated alpha-amylase in serum, thus the pancreatic disorder was put in question. A pancreatic disorder was proven in 9 children (9.7%) from this group. The authors consider the measurements given above to be the markers significantly improving the specificity of routine biochemistry in children with pancreatic diseases.
- MeSH
- akutní nemoc MeSH
- amylasy krev MeSH
- dítě MeSH
- klinické enzymatické testy * MeSH
- lidé MeSH
- mladiství MeSH
- nemoci slinivky břišní diagnóza MeSH
- předškolní dítě MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- předškolní dítě MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Názvy látek
- amylasy MeSH
