A woman's sexuality is a complex phenomenon involving several factors, among which age and health are the most important. However, other aspects are not negligible. The impact of pelvic organ prolapse on sexual function cannot be ignored, as the reported prevalence of pelvic organ prolapse in female population exceeds 50%. This article presents a systematic review of articles dealing with the impact of pelvic organ prolapse on female sexual function. Sexual dysfunction is common in women with pelvic organ prolapse, regardless of prolapse stage or the compartment affected. Estrogen therapy has no effect on sexuality in women with prolapse, while pelvic floor muscle training may provide some improvement. There is no evidence that conservative therapy using a pessary is associated with negative impact on sexual function. Native tissue repair tends to improve sexual function in general, except for posterior colporrhaphy, which was frequently associated with dyspareunia. No correlation between postoperative vaginal length and change in sexual function was identified. The impact of transvaginal mesh repair on sexuality remains unclear. In contrast, there is enough evidence proving that sacrocolpopexy significantly improves sexual function in women.

• Klíčová slova
• body image, descent of pelvic organs, native tissue repair, pelvic floor muscle training, pelvic organ prolapse, rehabilitation, sacrocolpopexy, sexual function, sexual functioning, transvaginal mesh repair,
• MeSH
• lidé MeSH
• prolaps pánevních orgánů * terapie   patofyziologie   komplikace   MeSH
• sexuální dysfunkce fyziologická * etiologie   patofyziologie   terapie   MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• systematický přehled MeSH

OBJECTIVE: The perineal body connects muscles from the pelvic floor and is critical for support of the lower part of the vagina and proper function of the anal canal. We determined mechanical parameters and volume fractions of main components of the human female postmenopausal perineal body. METHODS: The specimens were taken from 15 fresh female cadavers (age 74 ± 10, mean ± standard deviation). Seventy-five specimens from five regions of the perineal body were processed histologically to assess volume fractions of tissue components using stereological point testing grid. Fifteen specimens taken from the midline region were loaded uniaxially with 6 mm/min velocity until tissue rupture to determine Young's modulus of elasticity, ultimate stresses, and strains. RESULTS: The perineal body was composed of collagen (29%), adipose cells (27%), elastin (7%), smooth muscle (11%), and skeletal muscle (3%). The residual tissue (19%) constituted mostly peripheral nerves, lumina of blood vessels, fibroblasts, and fibrocytes. Young's modulus of elasticity at midline region was 18 kPa (median) at small and 232 kPa at large deformations, respectively. The ultimate stress was 172 kPa and the ultimate strain was 1.4. CONCLUSIONS: We determined the structural and mechanical parameters of the perineal body. The resultant data could be used as input for models simulating pelvic floor prolapse or dysfunction.

• MeSH
• anální kanál MeSH
• biomechanika fyziologie   MeSH
• elastin analýza   MeSH
• hladké svalstvo anatomie a histologie   MeSH
• kolagen analýza   MeSH
• kosterní svaly anatomie a histologie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mrtvola MeSH
• pánevní dno anatomie a histologie   fyziologie   chirurgie   MeSH
• perineum anatomie a histologie   fyziologie   chirurgie   MeSH
• postmenopauza fyziologie   MeSH
• prolaps pánevních orgánů patofyziologie   MeSH
• pružnost fyziologie   MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• tuková tkáň anatomie a histologie   MeSH
• vagina MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• elastin MeSH
• kolagen MeSH