The effect of stimulation of the anterior lobe (AL) of the cerebellum on spinobulbo-spinal (SBS) reflex activity evoked by somatic and splanchnic afferentation was studied in chloralose-anaesthetized cats. Unit activity synchronous with the SBS component of the efferent discharge was observed at the level of motoneurons, descending axons of the dorsolateral and ventral funiculi and neurones of the reticular formation (RF). Conditioning stimulation of the AL inhibited this unit activity. Reticular formation units influenced from the AL had direct contact with segmental structures; these results showed that disappearance of the SBS reflex during AL conditioning is associated with the depressant effect of the cerebellar cortex on the reticular formation.

• MeSH
• elektrická stimulace MeSH
• elektrofyziologie MeSH
• kočky MeSH
• mezižeberní nervy fyziologie   MeSH
• mícha fyziologie   MeSH
• motorické neurony fyziologie   MeSH
• mozeček fyziologie   MeSH
• reflex fyziologie   MeSH
• retikulární formace fyziologie   MeSH
• splanchnické nervy fyziologie   MeSH
• zadní končetina inervace   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

The influence of afferentation from the splanchnic region on the activity of long systems in the dorsolateral fascicle (DLF) was studied in chloralose-anaesthetized cats. Ascending axons (the dorsal spinocerebellar tract, DSCT and the spinocervical tract, SCT) did not respond to splanchnic stimuli. Conditioning from the splanchnic region modified their activity; the effect (mainly inhibitory) was strongest in the case of exteroceptive channels. The reaction of long propriospinal neurones depended on whether they belonged to ascending or descending pathways. No responses to splanchic stimuli were observed in the axons of ascending (proprioceptive, exteroceptive) units and conditioning from the splanchnic region only modified their activity. In decending axons, synaptic discharges with a long latent period (over 20 msec) were generated. The interaction of inputs from the visceral and somatosensory regions resulted in reciprocal inhibition of the tested activity. In axons descending from suprasegmental areas, splanchnic afferentation generated synaptic discharges with a time course comparable to spino-bulbo-spinal activity. Interaction with the responses from somatic nerves resulted inhibition of the tested activity. The results confirmed that the splanchnic region participates in modifying and evoking activity in the long DLF systems.

• MeSH
• aferentní nervové dráhy fyziologie   MeSH
• axony fyziologie   MeSH
• evokované potenciály MeSH
• interneurony fyziologie   MeSH
• kočky MeSH
• motorické neurony fyziologie   MeSH
• splanchnické nervy fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• dýchání * MeSH
• kočky MeSH
• reflex * MeSH
• splanchnické nervy fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

In experiments on the cats the relationship was studied of individual columns of the spinal cord to irradiation of the early (propriospinal) and late component of viscerosomatic reflex responses. It was found that the intraspinal systems involved in the descending spread of activity forming the early and the late component of the splanchnic response along the spinal cord were localized mainly in the anterolateral quadrants of the white matter. The descending systems are bilateral and cross at the segmental level. The pathways participating in the spread of the two-component somatomotor discharge evoked by intercostal nerve stimulation are localized in the same area. A bilateral lesion of the dorsal part of the lateral columns of segments C1 to C3 strongly inhibited the late component of the reflex responses. Inhibition was reversible, showing that systems modifying the development and course of the late component are localized in this region. Lesion-induced changes in viscerosomatic reflex responses were parallel with changes in somatomotor discharges. This finding supports the opinion that the pathways involved are localized close together and that their action is modified by similar factors.

• MeSH
• eferentní nervové dráhy fyziologie   MeSH
• kočky MeSH
• mezižeberní nervy fyziologie   MeSH
• mícha fyziologie   MeSH
• poranění míchy MeSH
• reflex * MeSH
• splanchnické nervy fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

• MeSH
• elektrická stimulace MeSH
• evokované potenciály MeSH
• hipokampus fyziologie   MeSH
• hypothalamus fyziologie   MeSH
• kočky MeSH
• somatosenzorické korové centrum fyziologie   MeSH
• spánek fyziologie   MeSH
• splanchnické nervy fyziologie   MeSH
• tenké střevo fyziologie   MeSH
• thalamus fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• mužské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

The functional characteristics of the intraspinal spread of the dual-component viscerosomatic reflex response were studied in chloralose-anaesthetized cats. In the region of the direct inputs of splanchnic afferents into the spinal cord, the initial part of the early (propriospinal) component is evoked by afflux from the extraspinal pathway in the sympathetic chain and has the shortest latent period. At segment Th8 to Th12 level this was 5.2--8.1 msec; cranially and caudally from this level it was longer. Activity spreading from the adjacent segments via intraspinal longitudinal systems also participates in the origin and course of the early component of the efferent discharge. The rate of ascending intraspinal irradiation in the thoracic region was 3.2--12 m/sec (6.6 +/- 2.4 m/sec). The rate of the descending spread of propriospinal activity in the thoracic region via intraspinal pathways was 3.6--18.3 m/sec (12.5 +/- 4.5 m/sec); in the lumbar region it was significantly lower -- 2.9--19.3 m/sec (7 +/- 4.5 m/sec). The latent period of the later component varied from 20 to 30 msec and displayed a cranio-caudal increase in length. The rate of the descending spread of the later component in the thoracic and lumbar cord did not differ significantly (20 +/- 10 m/sec and 22 +/- 13 m/sec respectively). The continuous splanchnic discharge in the lumbosacral region is correlated to the different rate of the intraspinal spread of the early and the late response and to their overlapping.

• MeSH
• časové faktory MeSH
• kočky MeSH
• mícha anatomie a histologie   fyziologie   MeSH
• motorické neurony fyziologie   MeSH
• nervové dráhy fyziologie   MeSH
• nervový přenos MeSH
• reflex * MeSH
• splanchnické nervy fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

The interaction of visceral and somatic afferentation at the level of postsynaptic spinal cord elements was studied in cats. The effect of conditioning stimuli on the propriospinal (PS) and suprasegmental (SS) component of the tested unit responses was compared. Afferentation from the splanchnic nerve completely inhibited the SS component of somatomotor motoneuronal responses; the PS component was only partly inhibited. Inhibition persisted even after the conditioning stimulus-induced changes in the membrane potential of the motoneurones had disappeared. The activity of the interneurones responsing synchronously with the SS component of the efferent discharges was also completely inhibited in the same intervals. The inhibitory effect of splanchnic afferentation on the PS component of interneuronal discharges evoked by the stimulation of somatic afferents was significantly less effective. The results of interaction for test responses from the cutaneous and muscular nerves was the same. When splanchnic responses were tested during conditioning from somatosensory areas, inhibitory control was found to be reciprocal. The authors discuss the question of the structures and mechanisms participating in functional relations between the autonomic and somatic nervous system in the spinal cord.

• MeSH
• aferentní nervové dráhy fyziologie   MeSH
• elektrická stimulace MeSH
• interneurony fyziologie   MeSH
• kočky MeSH
• kůže inervace   MeSH
• membránové potenciály MeSH
• mícha fyziologie   MeSH
• motorické neurony fyziologie   MeSH
• splanchnické nervy fyziologie   MeSH
• svaly inervace   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

The relationship between the activity of the lumbar spinal interneurones and propriospinal (PS) and spino-bulbo-spinal (SBS) efferent reflex responses evoked by somatic (muscle, skin) and splanchnic nerve stimulation was studied in chloralose-anaestetized adult cats. During stimulation of one somatic nerve, the postsynaptic cord elements could be divided into three groups, according to whether their activity was was synchronous with the PS component of the efferent discharge (PS group), with the SBS component (SBS group) or with both (PS-SBS-group). Group SBS and PS-SBS interneurones were localized in the ventral quadrant of the grey matter. On stimulation of different nerves, the same interneurone could in one case respond synchronously with the PS component of the efferent discharge and in another with the SBS component. The membrane of units which did not generate propagated spike potentials during PS or SBS reflex activity was hyperpolarized in this period, or failed to display changes characteristic for postsynaptic inhibition. Convergence of somatic and visceral afferentation was observed in all three groups of postsynaptic elements. In type PS-SBS and SBS units it was massive (occurring in 85% and 100% of the cases respectively). The results confirmed the intimacy of functional contact of PS and SBS systems activated by somatic and visceral afferents.

• MeSH
• evokované potenciály MeSH
• fyzikální stimulace MeSH
• interneurony fyziologie   MeSH
• kočky MeSH
• kůže inervace   MeSH
• medulla oblongata fyziologie   MeSH
• membránové potenciály MeSH
• mícha fyziologie   MeSH
• motorické neurony fyziologie   MeSH
• nervový přenos MeSH
• neurony eferentní fyziologie   MeSH
• reflex * MeSH
• splanchnické nervy fyziologie   MeSH
• svaly inervace   MeSH
• synapse fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

The splanchnic afferent signal in the myelinated fibre spectrum was analysed in cats and its relationship to viscerosomatic reflex activity was studied. In addition to Abeta and Adelta components, a further elevation was observed in the sympathetic chain neurogram. According to the conduction rate (15 plus or minus 4 m/sec), it was caused by myelinated fibres 2-3 mu in diameter. The presence of this component at thoracic dorsal root level, or in the sympathetic chain in stimulation of the postganglionic part of the nerve trunk, confirmed the afferent nature of the observed activity. The threshold stimulus for these fibres, which were termed group Adelta2, was four times higher than for Abeta fibres. Correlation of the neurogram with evoked activity in the intercostal nerves confirmed the different functional role of group Adelta2 fibres. Adelta2 fibre activity evokes the early component of the two-component viscerosomatic discharge and Adelta2 fibre activity its later component. The authors discuss the functional significance of Adelta2 fibres, which probably mediate nociceptive information from the viscera.

• MeSH
• evokované potenciály MeSH
• kočky MeSH
• mezižeberní nervy fyziologie   MeSH
• nervová vlákna myelinizovaná fyziologie   MeSH
• nervový přenos MeSH
• neurony aferentní fyziologie   MeSH
• neurony eferentní fyziologie   MeSH
• reflex * MeSH
• splanchnické nervy cytologie   fyziologie   MeSH
• zvířata MeSH
• Check Tag
• kočky MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH