Nejvíce citovaný článek - PubMed ID 11898349
Particulate 1,3-beta-D-glucan, carboxymethylglucan and sulfoethylglucan--influence of their oral or intraperitoneal administration on immunological respondence of mice
Among 18 tested strains of Claviceps spp., 7 produced significant amounts of exocellular polysaccharide (EPS). The maximum production of EPS was found in fermentation broth of Claviceps viridis. The kinetics of growth, substrate consumption, and EPS production in the batch, aerobic, submerged culture of this fungus were investigated in detail. The experimental data were processed by a simple mathematical model describing mass balance of growth, substrate consumption, formation of intermediates, and production of EPS. The parameters of the model were estimated from data obtained in cultivation performed in flasks and two laboratory fermentors of different size. Physiological similarity was obtained during process scale-up in volumetric ratio 1:100. The sugar consumption efficiency (52%) and observed EPS productivity (1.9 kg/m3 per d) were comparable with literature data.
- MeSH
- biologické modely MeSH
- biomasa MeSH
- Claviceps růst a vývoj metabolismus MeSH
- fermentace MeSH
- glukany biosyntéza MeSH
- kinetika MeSH
- kultivační média MeSH
- kyslík metabolismus MeSH
- rozpustnost MeSH
- sacharosa metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- glukany MeSH
- kultivační média MeSH
- kyslík MeSH
- sacharosa MeSH