Prevention of type 2 diabetes (T2D) is a great challenge worldwide. The aim of this evidence synthesis was to summarize the available evidence in order to update the European Association for the Study of Diabetes (EASD) clinical practice guidelines for nutrition therapy. We conducted a systematic review and, where appropriate, meta-analyses of randomized controlled trials (RCTs) carried out in people with impaired glucose tolerance (IGT) (six studies) or dysmetabolism (one study) to answer the following questions: What is the evidence that T2D is preventable by lifestyle changes? What is the optimal diet (with a particular focus on diet quality) for prevention, and does the prevention of T2D result in a lower risk of late complications of T2D? The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach was applied to assess the certainty of the trial evidence. Altogether seven RCTs (N = 4090) fulfilled the eligibility criteria and were included in the meta-analysis. The diagnosis of incident diabetes was based on an oral glucose tolerance test (OGTT). The overall risk reduction of T2D by the lifestyle interventions was 0.53 (95% CI 0.41; 0.67). Most of the trials aimed to reduce weight, increase physical activity, and apply a diet relatively low in saturated fat and high in fiber. The PREDIMED trial that did not meet eligibility criteria for inclusion in the meta-analysis was used in the final assessment of diet quality. We conclude that T2D is preventable by changing lifestyle and the risk reduction is sustained for many years after the active intervention (high certainty of evidence). Healthy dietary changes based on the current recommendations and the Mediterranean dietary pattern can be recommended for the long-term prevention of diabetes. There is limited or insufficient data to show that prevention of T2D by lifestyle changes results in a lower risk of cardiovascular and microvascular complications.

• Klíčová slova
• complications, diet, lifestyles, prevention, type 2 diabetes,
• MeSH
• cvičení * MeSH
• diabetes mellitus 2. typu prevence a kontrola   MeSH
• dieta * MeSH
• glukózový toleranční test MeSH
• komplikace diabetu prevence a kontrola   MeSH
• lidé MeSH
• zdravé chování * MeSH
• životní styl * MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• metaanalýza MeSH
• systematický přehled MeSH

The objective of the paper was to investigate the association between PA and general life satisfaction in adolescents, taking into account family affluence and selected psychological, family and school factors. The survey (2015) involved 4085 Polish lower-secondary school students. Life satisfaction was measured with the abridged Students' Life Satisfaction Scale (SLSS). Vigorous Physical Activity, self-esteem, family affluence, family relations and the perception of the school environment were considered as independent variables. Hierarchical and path models were applied. The mean SLSS score was M = 4.66 (SD = 2.23), and 36.9% of its variability was explained-mainly by self-esteem. The impact of PA on self-esteem became stronger when family affluence decreased, which led to the conclusion that material status may modify the impact of behavioural factors on the SLSS scores' variability in adolescence.

• Klíčová slova
• Adolescents, Family affluence, Life satisfaction, Physical activity, Self-esteem,
• MeSH
• cvičení * psychologie   MeSH
• lidé MeSH
• mladiství MeSH
• osobní uspokojení * MeSH
• rodina psychologie   MeSH
• sebepojetí MeSH
• školy MeSH
• studenti psychologie   statistika a číselné údaje   MeSH
• Check Tag
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH