THEORETICAL BASIS: A sedentary lifestyle, consumption of inappropriate food, smoking or alcohol consumption can contribute to the overall deterioration of lifestyle and lead to weight gain. Lifestyle includes nutrition, physical activity, sleep, psychological well-being, good relationships or job satisfaction. We can influence some parts of our lifestyle, but we cannot influence many other factors like genetic predisposition or the environment in which we live. OBJECTIVE OF STUDY: The objective of the study is to evaluate the relationship between lifestyle and BMI (Body Mass Index), as well as differences based on age and sex. METHODOLOGY: A self-constructed questionnaire containing 71 questions was used to determine information about lifestyle. The collected data was based on the assessment of body mass index (BMI) and age, all respondents were measured using the stadiometer and InBody 270. The group included 323 adults (156 men and 167 women) and was divided according to BMI (BMI lower than 25 kg/m2, and BMI of 25 kg/m2 or higher). The selected lifestyle characteristics were grouped to create a positive score including positive lifestyle factors, a negative score including negative lifestyle factors, and an overall healthy lifestyle score that included positive and negative scores. RESULTS: We found out that physiological BMI (18.5-24.9 kg/m2) was more common in respondents with higher education and students. The most respondents prefer omnivorous diet, in lower BMI group were mainly non-smokers and occasional consumers of alcohol, in comparison to higher BMI group where were former smokers and those who abstained from alcohol. All scales of lifestyle are sex-related and negative healthy lifestyle score also depend on BMI. Effect of age is not significant. CONCLUSIONS: According to our study, people with a physiological BMI have a significantly healthier lifestyle compared to overweight or obese people. The overall lifestyle values, as well as the positive and negative lifestyle scores, depend on sex; the negative healthy lifestyle score also depends on BMI.

• MeSH
• dieta MeSH
• dospělí MeSH
• index tělesné hmotnosti MeSH
• lidé MeSH
• obezita * epidemiologie   MeSH
• zdravý životní styl * MeSH
• životní styl MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a neurological/behavioral disorder characterized by inattention or hyperactivity and impulsivity, or combined symptomatology. Children with ADHD are predisposed to irregular and/or impulsive eating patterns often leading to compromised physical condition. The goal of the present study was to statistically evaluate parental scoring of patterned eating behaviors and associated lifestyles within a cohort of 100 boys diagnosed with ADHD in comparison to age-matched male controls. MATERIAL AND METHODS: The study population consisted of 100 boys aged 6-10 years diagnosed with mixed type ADHD by DSM-IV criteria and 100 aged-matched healthy male control subjects. Patterns of eating behaviors and associated lifestyles were scored by structured parental interviews using a nominal rating scale. RESULTS: Interview scores indicated statistically significant differences in patterned eating behaviors in subjects with ADHD in comparison to healthy controls. Notably, subjects diagnosed with ADHD exhibited markedly diminished adherence to a traditional breakfast, lunch, and dinner schedule, which was linked to a significantly higher frequency (>5/day) of irregular eating times. In the ADHD cohort, disruptive patterns of eating behaviors were associated with diminished nutritional value of ingested food (expressed as lowered content of fruits and vegetables) and increased consumption of sweetened beverages. CONCLUSIONS: Disruptive patterns of eating behaviors, metabolically unfavorable nutritional status, and diminished physical activities of male children diagnosed with ADHD are linked to compromised growth and development and appearance of metabolic diseases in adulthood.

• MeSH
• dítě MeSH
• hyperkinetická porucha komplikace   MeSH
• kojení MeSH
• lidé MeSH
• ovoce MeSH
• počítače MeSH
• stravovací zvyklosti * MeSH
• studie případů a kontrol MeSH
• televize MeSH
• zelenina MeSH
• životní styl * MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH

BACKGROUND: It is not clear whether the effects of lipid-lowering or antihypertensive medications are influenced by adherence to healthy lifestyle factors. We assessed the effects of both drug interventions in subgroups by the number of healthy lifestyle factors in participants in the HOPE-3 (Heart Outcomes Prevention Evaluation) trial. METHODS AND RESULTS: In this primary prevention trial, 4 healthy lifestyle factors (nonsmoking status, physical activity, optimal body weight, and healthy diet) were recorded in 12 521 participants who were at intermediate risk of cardiovascular disease (CVD) and were randomized to rosuvastatin, candesartan/hydrochlorothiazide, their combination, or matched placebos. Median follow-up was 5.6 years. The outcome was a composite of CVD events. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models. Participants with ≥2 healthy lifestyle factors had a lower rate of CVD compared with those with fewer factors (HR: 0.85; 95% CI, 0.73-1.00). Rosuvastatin reduced CVD events in participants with ≥2 healthy lifestyle factors (HR: 0.74; 95% CI, 0.62-0.90) and in participants with <2 factors (HR: 0.79; 95% CI, 0.61-1.01). Consistent results were observed with combination therapy (≥2 factors: HR: 0.74; 95% CI, 0.57-0.97; <2 factors: HR: 0.61; 95% CI, 0.43-0.88). Candesartan/hydrochlorothiazide tends to reduce CVD only in participants with <2 healthy lifestyle factors (HR: 0.78; 95% CI, 0.61-1.00). CONCLUSIONS: Healthy lifestyles are associated with lower CVD. Rosuvastatin alone and combined with candesartan/hydrochlorothiazide is beneficial regardless of healthy lifestyle status; however, the benefit of antihypertensive treatment appears to be limited to patients with less healthy lifestyles. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov. Unique identifier: NCT00239681.

• Klíčová slova
• antihypertensive agent, statin,
• MeSH
• anticholesteremika terapeutické užití   MeSH
• antihypertenziva terapeutické užití   MeSH
• benzimidazoly terapeutické užití   MeSH
• bifenylové sloučeniny MeSH
• dvojitá slepá metoda MeSH
• hydrochlorthiazid terapeutické užití   MeSH
• kardiovaskulární nemoci krev   prevence a kontrola   MeSH
• kombinovaná farmakoterapie MeSH
• LDL-cholesterol krev   MeSH
• lidé středního věku MeSH
• lidé MeSH
• primární prevence metody   MeSH
• rizikové faktory MeSH
• rosuvastatin kalcium terapeutické užití   MeSH
• senioři MeSH
• tetrazoly terapeutické užití   MeSH
• výsledek terapie MeSH
• zdravý životní styl * MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• multicentrická studie MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH
• Názvy látek
• anticholesteremika MeSH
• antihypertenziva MeSH
• benzimidazoly MeSH
• bifenylové sloučeniny MeSH
• candesartan MeSH Prohlížeč
• hydrochlorthiazid MeSH
• LDL-cholesterol MeSH
• rosuvastatin kalcium MeSH
• tetrazoly MeSH

Sauropterygia, a successful clade of marine reptiles abundant in aquatic ecosystems of the Mesozoic, inhabited nearshore to pelagic habitats over >180 million years of evolutionary history [1]. Aquatic vertebrates experience strong buoyancy forces that allow movement in a three-dimensional environment, resulting in structural convergences such as flippers and fish-like bauplans [2, 3], as well as convergences in the sensory systems. We used computed tomographic scans of 19 sauropterygian species to determine how the transition to pelagic lifestyles influenced the evolution of the endosseous labyrinth, which houses the vestibular sensory organ of balance and orientation [4]. Semicircular canal geometries underwent distinct changes during the transition from nearshore Triassic sauropterygians to the later, pelagic plesiosaurs. Triassic sauropterygians have dorsoventrally compact, anteroposteriorly elongate labyrinths, resembling those of crocodylians. In contrast, plesiosaurs have compact, bulbous labyrinths, sharing some features with those of sea turtles. Differences in relative labyrinth size among sauropterygians correspond to locomotory differences: bottom-walking [5, 6] placodonts have proportionally larger labyrinths than actively swimming taxa (i.e., all other sauropterygians). Furthermore, independent evolutionary origins of short-necked, large-headed "pliosauromorph" body proportions among plesiosaurs coincide with reductions of labyrinth size, paralleling the evolutionary history of cetaceans [7]. Sauropterygian labyrinth evolution is therefore correlated closely with both locomotory style and body proportions, and these changes are consistent with isolated observations made previously in other marine tetrapods. Our study presents the first virtual reconstructions of plesiosaur endosseous labyrinths and the first large-scale, quantitative study detailing the effects of increasingly aquatic lifestyles on labyrinth morphology among marine reptiles.

• Klíčová slova
• Mesozoic, ecomorphology, endosseous labyrinth, geometric morphometrics, paleoecology, semicircular canals,
• MeSH
• biologická evoluce * MeSH
• ekosystém * MeSH
• plavání MeSH
• plazi anatomie a histologie   fyziologie   MeSH
• počítačová rentgenová tomografie MeSH
• vnitřní ucho anatomie a histologie   MeSH
• zkameněliny anatomie a histologie   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH

Women live longer than men and experience lower overall and specific mortality resulting from various diseases, even when younger. The reasons for this have yet to be satisfactorily explained. However, biological differences on one hand and differing lifestyles on the other might be responsible. The purpose of the study was to examine to what extent the lifestyle of men and women differs within a relatively homogeneous population group. The lifestyles of 4,353 parents of school age children (58% women and 42% men) were examined using questionnaires. The results show considerable differences between the genders. Men had worse dietary habits--consuming significantly less vegetables, fruit and milk, but too much meat; they consumed more processed meat and fat-containing items within the food sub-categories; they preferred less low-fat milk products and consumed less wholemeal products. Men more often consumed alcohol, drank more of it and often crossed the limits hazardous for health. There were more smokers among the men, they smoked more cigarettes and the non-smokers more often indicated passive exposure to cigarette smoke. Overweight and obesity occurred more often among men. Relatively minor differences, rather to the benefit of men, occurred in the field of leisure-time physical sporting activities, where slightly more men pursued regular sporting activities but in significantly higher amounts than the women, whereas the men did less regular daily walking. Women, as opposed to men, displayed more interest in comprehensive primary preventive medical examinations. The results obtained suggest that women lived a generally more healthy lifestyle than men within the examined homogeneous group of parents of school age children, consisting mostly of pairs of partners. They support the assumption that the healthier lifestyle of women very significantly contributes to their lower mortality.

• MeSH
• cvičení MeSH
• dieta MeSH
• dospělí MeSH
• kouření epidemiologie   MeSH
• lidé MeSH
• mortalita MeSH
• muži výchova   psychologie   MeSH
• obezita epidemiologie   MeSH
• pití alkoholu epidemiologie   MeSH
• průzkumy a dotazníky MeSH
• rodiče výchova   psychologie   MeSH
• výživová politika MeSH
• zdravé chování * MeSH
• zdraví ve městech MeSH
• zdravotnické přehledy MeSH
• ženy výchova   psychologie   MeSH
• životní styl * MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• srovnávací studie MeSH
• Geografické názvy
• Česká republika epidemiologie   MeSH

Sponges are among the oldest metazoans and their success is partly due to their abundant and diverse microbial symbionts. They are one of the few animals that have Thaumarchaeota symbionts. Here we compare genomes of 11 Thaumarchaeota sponge symbionts, including three new genomes, to free-living ones. Like their free-living counterparts, sponge-associated Thaumarchaeota can oxidize ammonia, fix carbon, and produce several vitamins. Adaptions to life inside the sponge host include enrichment in transposases, toxin-antitoxin systems and restriction modifications systems, enrichments previously reported also from bacterial sponge symbionts. Most thaumarchaeal sponge symbionts lost the ability to synthesize rhamnose, which likely alters their cell surface and allows them to evade digestion by the host. All but one archaeal sponge symbiont encoded a high-affinity, branched-chain amino acid transporter system that was absent from the analyzed free-living thaumarchaeota suggesting a mixotrophic lifestyle for the sponge symbionts. Most of the other unique features found in sponge-associated Thaumarchaeota, were limited to only a few specific symbionts. These features included the presence of exopolyphosphatases and a glycine cleavage system found in the novel genomes. Thaumarchaeota have thus likely highly specific interactions with their sponge host, which is supported by the limited number of host sponge species to which each of these symbionts is restricted.

• Klíčová slova
• Hymedesmia (Stylopus) methanophila, Petrosia ficiformis, Theonella swinhoei, archaea, sponge (Porifera), symbiosis, thaumarchaeota,
• Publikační typ
• časopisecké články MeSH

BACKGROUND: The economic crisis in Italy has led to profound changes in resource management not only at the macro level but also for individual families, causing substantial changes in different habits of Italians. STUDY DESIGN: The purpose of this research was to conduct a study on changes in family eating habits potentially triggered by the economic crisis was conducted in an area of the Marche Region in central Italy. METHODS: The research was conducted in the period 2016 - 2017 by administering a specific and anonymous questionnaire. RESULTS: The interviewed people has reduced its food consumption. In particular, analyzing the results for the animal protein food group, there has been a reduction in purchase of beef, and an increase in that of pork. Overall fish consumption has decreased by 44%, with a decrease in the purchase of fresh fish, and an increase in that of canned fish products. Finally, consumers have reduced their purchases of fresh and canned legumes, fresh vegetables, and fresh fruit. CONCLUSION: The economic crisis seems to have changed the eating habits and food-related lifestyle choices of the subjects studied, especially in the urban area affected by the deeper economic depression. These changes are likely to have permanent social consequences, and deserve to be analyzed also in smaller territories in order to better understand the dynamics of individual choices and the social framework.

• Klíčová slova
• Diet habits, Economic crisis, Food choices, Human health,
• MeSH
• dospělí MeSH
• ekonomická recese * MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• stravovací zvyklosti * MeSH
• výběrové chování MeSH
• životní styl * MeSH
• zpráva o sobě MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Itálie MeSH

The review examines Attention Deficit Hyperactivity Disorder (ADHD in its Child and Adult form) and its various presentations (Hyperactive Impulsive, Inattentive, and Combined) with a particular focus on environmental (incl. social factors), lifestyles and comorbidities. It is argued that ADHD is best understood in a holistic and interactive context and a vast empirical literature is presented to illustrate the point: Environmental factors include stress in general as well as exposure to toxins (phthalates, bisphenol A). Social factors are illustrated by effects of social deprivation and seduction to unhealthy lifestyles. Maternal lifestyle during pregnancy is pointed out (particularly her exposure to nicotine, alcohol, caffeine, and drugs, even seemingly benign medications like acetaminophen), which all tend to be related to ADHD. Family environment is discussed with respect to protective effect of (mainly authoritative and autocratic) parenting styles. Societal factors include mainly economic and political issues: income inequality and poverty (low SES is an ADHD risk factor) and a growing moral dilemma between a humanistic effort to globally spread the knowledge of ADHD and the medicalization and commercialization of the disorder. The second part of the review is devoted to ADHD related lifestyles and resulting comorbidities (e.g., food addiction and obesity, substance abuse, electronic media dependencies and conduct and personality disorders). Although ADHD is a neurodevelopmental disorder, its assessment and treatment are also linked to environmental, behavioral and social factors and their interactions.

• Klíčová slova
• ADHD, alcohol, childhood, comorbidities, obesity, pollution, smoking, substance abuse,
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

This paper presents a study that examined desired functionality, content, and design of a mobile application for young Czech adults living with Multiple Sclerosis (MS). The study was structured around a high-fidelity prototype developed for the corresponding user group in Norway. Both groups were active on social media and willing to contribute to designing an application promoting a healthy lifestyle and well-being. Adopting the content analysis, the study first compared the social content shared within the Facebook communities in the Norwegian and Czech user groups that were active. Regardless of the similarities, the Czech group expected that solutions regarding main functionalities and content should stand out from other competitive applications offered on the market. Most of all, they would like to see healthcare staff being engaged in content creation by providing credible information, especially regarding new treatments and clinical trials. Enhanced interaction between all the stakeholders (patients, and healthcare providers) would add value and relevance to the content already provided by social media.

• Klíčová slova
• Lifestyle application, Multiple Sclerosis (MS), User-Centered Design (UCD), Young adults,
• MeSH
• dospělí MeSH
• lidé MeSH
• mobilní aplikace * MeSH
• roztroušená skleróza * terapie   MeSH
• zdravý životní styl MeSH
• životní styl MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

Human consumption and activity are damaging the global ecosystem and the resources on which we rely for health, well-being and survival. The COVID-19 crisis is yet another manifestation of the urgent need to transition to more sustainable societies, further exposing the weaknesses in health systems and the injustice in our societies. It also underlines that many of the factors leading to environmental degradation, ill health and social and health inequities are interlinked. The current situation provides an unprecedented opportunity to invest in initiatives that address these common factors and encourage people to live more healthily and sustainably. Such initiatives can generate the positive feedback loops needed to change the systems and structures that shape our lives. INHERIT (January 2016-December 2019), an ambitious, multisectoral and transnational research project that involved 18 organisations across Europe, funded by the European Commission, explored such solutions. It identified, defined and analysed promising inter-sectoral policies, practices and approaches to simultaneously promote environmental sustainability, protect and promote health and contribute to health equity (the INHERIT "triple-win") and that can encourage and enable people to live, move and consume more healthfully and sustainably. It also explored the facilitators and barriers to working across sectors and in public private cooperation. The insights were brought together in guidelines setting out how policy makers can help instigate and support local "triple-win" initiatives that influence behaviours as an approach to contributing to the change that is so urgently needed to stem environmental degradation and the interlinked threats to health and wellbeing. This article sets out this guidance, providing timely insights on how to "build back better" in the post pandemic era.

• Klíčová slova
• behaviour change, environment, equity, health, health equity, intersectoral cooperation, policy, sustainable development, systemic change,
• MeSH
• COVID-19 MeSH
• koronavirové infekce MeSH
• lidé MeSH
• pandemie MeSH
• trvale udržitelný rozvoj * MeSH
• virová pneumonie MeSH
• zachování přírodních zdrojů * MeSH
• životní styl * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH
• Geografické názvy
• Evropa MeSH