The present study evaluated whether drug-induced sleep endoscopy (DISE) helps identify the site of obstruction in patients with obstructive sleep apnoea (OSA). A total of 51 consecutive patients with polysomnography-confirmed OSA were enrolled in this prospective study. The presumed site of obstruction was determined according to history, otorhinolaryngologic examination, and polysomnography and a therapeutic plan designed before DISE. In 11 patients with severe OSA and/or previously failed continuous positive airway pressure (CPAP) treatment, DISE with simultaneous CPAP was performed. Multilevel collapse was noted in 49 patients (96.1%). The most frequent multilevel collapse was palatal, oropharyngeal, and tongue base collapse (n = 17, 33.3%), followed by palatal and oropharyngeal collapse (n = 12, 23.5%). Pathology of the larynx (epiglottis) was observed in 16 patients (31.4%). The laryngeal obstruction as a reason for intolerance of CPAP was observed in 3/11 (27.3%) patients. After DISE, the surgical plan was changed in 31 patients (60.8%). The results indicate that DISE helps identify the site of obstruction in the upper airways in patients with OSA more accurately and that the larynx plays an important role in OSA.

• MeSH
• anestetika intravenózní aplikace a dávkování   MeSH
• anestetika lokální MeSH
• dospělí MeSH
• endoskopie metody   MeSH
• epiglotis patofyziologie   MeSH
• jazyk chirurgie   MeSH
• larynx patologie   chirurgie   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• obstrukce dýchacích cest patofyziologie   MeSH
• obstrukční spánková apnoe terapie   MeSH
• orofarynx patofyziologie   MeSH
• otorinolaryngologie MeSH
• polysomnografie metody   MeSH
• propofol aplikace a dávkování   MeSH
• prospektivní studie MeSH
• spánek MeSH
• trvalý přetlak v dýchacích cestách MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• anestetika intravenózní MeSH
• anestetika lokální MeSH
• propofol MeSH