The knowledge of the structure, function, and abundance of specific proteins related to the EMT process is essential for developing effective diagnostic approaches to cancer with the perspective of diagnosis and therapy of malignancies. The success of all-trans retinoic acid (ATRA) differentiation therapy in acute promyelocytic leukemia has stimulated studies in the treatment of other tumors with ATRA. This review will discuss the impact of ATRA use, emphasizing epithelial-mesenchymal transition (EMT) proteins in breast cancer, of which metastasis and recurrence are major causes of death.

• Klíčová slova
• ATRA, EMT, breast cancer, protein,
• MeSH
• epitelo-mezenchymální tranzice * MeSH
• lidé MeSH
• metastázy nádorů MeSH
• nádorové proteiny agonisté   metabolismus   MeSH
• nádory prsu metabolismus   mortalita   patologie   MeSH
• receptory kyseliny retinové agonisté   metabolismus   MeSH
• tretinoin metabolismus   MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Názvy látek
• nádorové proteiny MeSH
• receptory kyseliny retinové MeSH
• tretinoin MeSH