The knowledge of the structure, function, and abundance of specific proteins related to the EMT process is essential for developing effective diagnostic approaches to cancer with the perspective of diagnosis and therapy of malignancies. The success of all-trans retinoic acid (ATRA) differentiation therapy in acute promyelocytic leukemia has stimulated studies in the treatment of other tumors with ATRA. This review will discuss the impact of ATRA use, emphasizing epithelial-mesenchymal transition (EMT) proteins in breast cancer, of which metastasis and recurrence are major causes of death.

• Keywords
• ATRA, EMT, breast cancer, protein,
• MeSH
• Epithelial-Mesenchymal Transition * MeSH
• Humans MeSH
• Neoplasm Metastasis MeSH
• Neoplasm Proteins agonists   metabolism   MeSH
• Breast Neoplasms metabolism   mortality   pathology   MeSH
• Receptors, Retinoic Acid agonists   metabolism   MeSH
• Tretinoin metabolism   MeSH
• Animals MeSH
• Check Tag
• Humans MeSH
• Female MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Review MeSH
• Names of Substances
• Neoplasm Proteins MeSH
• Receptors, Retinoic Acid MeSH
• Tretinoin MeSH