Most cited article - PubMed ID 34833268
Chelators for Treatment of Iron and Copper Overload: Shift from Low-Molecular-Weight Compounds to Polymers
We constructed a sensor for the determination of Fe2+ and/or Fe3+ ions that consists of a polyaniline layer as an ion-to-electron transducer; on top of it, chelating molecules are deposited (which can selectively chelate specific ions) and protected with a non-biofouling poly(2-methyl-2-oxazoline)s layer. We have shown that our potentiometric sensing layers show a rapid response to the presence of Fe2+ or Fe3+ ions, do not experience interference with other ions (such as Cu2+), and work in a biological environment in the presence of bovine serum albumin (as a model serum protein). The sensing layers detect iron ions in the concentration range from 5 nM to 50 µM.
- Keywords
- analysis, non-biofouling layer, poly(2-methyl-2-oxazoline)s, potentiometry, sensor of Fe2+ or Fe3+ ions,
- MeSH
- Aniline Compounds MeSH
- Chelating Agents * MeSH
- Electrodes MeSH
- Ion-Selective Electrodes * MeSH
- Ions MeSH
- Hydrogen-Ion Concentration MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Aniline Compounds MeSH
- Chelating Agents * MeSH
- Ions MeSH
- polyaniline MeSH Browser