PURPOSE OF REVIEW: Arthritis is a well-recognized symptom of idiopathic inflammatory myopathies (IIM). We provide a summary of available data regarding the epidemiology, clinical characteristics, and autoantibody associations of joint involvement in various forms of IIM. RECENT FINDINGS: Arthritis is reported in 18-55% of patients with IIM. It is particularly frequent (20-70%) in those with antisynthetase syndrome (ASS); highest prevalence is associated with anti-Jo-1 positivity. Most common manifestation is non-erosive polyarthritis. X-ray erosions may be found occasionally in ASS, particularly in patients with overlap with rheumatoid arthritis (RA). Arthritis is often present at the time of IIM diagnosis and it may even precede the onset of muscle weakness. Arthritis may in some cases be the main disease manifestation responsible for the disease burden in patients with IIM. Arthritis is a frequent symptom of IIM. Polyarthritis of small joints of the hands is the most frequent clinical manifestation. Arthritis may be the first or dominant symptom in IIM and therefore patients may be initially misdiagnosed as having RA. Particularly in seronegative RA patients with interstitial lung disease or Raynaud's phenomenon, the possibility of IIM should be considered.

• Klíčová slova
• Anti-Jo-1, Antisynthetase syndrome, Arthritis, Floppy-thumb, Idiopathic inflammatory myopathies,
• MeSH
• artritida diagnóza   epidemiologie   MeSH
• lidé MeSH
• myozitida komplikace   diagnóza   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• přehledy MeSH

• MeSH
• artritida epidemiologie   MeSH
• autoprotilátky * MeSH
• HLA-DQ beta řetězec genetika   MeSH
• HLA-DRB1 řetězec genetika   MeSH
• lidé MeSH
• myozitida epidemiologie   MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• dopisy MeSH
• komentáře MeSH
• Názvy látek
• autoprotilátky * MeSH
• HLA-DQ beta řetězec MeSH
• HLA-DRB1 řetězec MeSH

PURPOSE OF THE STUDY This study examines the risk of falling in elderly patients who underwent hip fracture surgery in the orthopaedic clinic during the postoperative period. MATERIALS AND METHODS This study was a cross-sectional study. The study sample consisted of 71 elderly patients aged more than 65 years undergoing hip fracture surgery. A questionnaire, the Tinetti balance test and the mini-mental state examination (MMSE) were used. RESULTS The analyses included 71 elderly patients with a mean age of 78.45 years. All patients had been hospitalized for hip fracture due to falling, and 29.6% had a history of falling in the one year prior to hospitalization. The mean MMSE score was 18.37 ± 6.54 and the mean Tinetti score was 11.10 ± 6.66. CONCLUSION We found that as the mean age of the elderly patients increased, the risk of falling also increased and the MMSE scores deteriorate and that the elderly patients living alone were at a greater risk of falling and had worse cognitive function, that those with a history of falling before hospitalization were at a greater risk of falling again and that the risk of falling increased as cognitive function declined. Key words:elderly, falling, hip fracture, risk of falling.

• MeSH
• artritida epidemiologie   MeSH
• cerebrovaskulární poruchy epidemiologie   MeSH
• činnosti denního života MeSH
• fraktury kyčle epidemiologie   chirurgie   MeSH
• hodnocení rizik MeSH
• kardiovaskulární nemoci epidemiologie   MeSH
• kauzalita MeSH
• komorbidita MeSH
• lidé MeSH
• pooperační komplikace epidemiologie   MeSH
• poruchy zraku epidemiologie   MeSH
• průřezové studie MeSH
• senioři MeSH
• úrazy pádem statistika a číselné údaje   MeSH
• životní styl MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

OBJECTIVE: To determine the prevalence, distribution, and clinical manifestations of arthritis in a cohort of patients with idiopathic inflammatory myopathies (IIM). Associations with autoantibody status and HLA genetic background were also explored. METHODS: Consecutive patients with IIM treated in a single center were included in this cross-sectional study (n = 106). History of arthritis, 68-joint and 66-joint tender and swollen joint index, clinical features of IIM, and autoantibody profiles were obtained by clinical examination, personal interview, and review of patient records. High-resolution genotyping in HLA-DRB1 and HLA-DQB1 loci was performed in 71 and 73 patients, respectively. RESULTS: A combination of patients' medical history and cross-sectional physical examination revealed that arthritis at any time during the disease course had occurred in 56 patients (53%). It was present at the beginning of the disease in 39 patients (37%) including 23 cases (22%) with arthritis preceding the onset of muscle weakness. On physical examination, 29% of patients had at least 1 swollen joint. The most frequently affected areas were wrists, and metacarpophalangeal and proximal interphalangeal joints. Twenty-seven out of the 29 anti-Jo1-positive patients had arthritis at any time during the course of their illness; this prevalence was significantly higher compared to patients without the anti-Jo1 autoantibody (p < 0.0001). No association of arthritis with individual HLA alleles was found. CONCLUSION: Our data suggest that arthritis is a common feature of myositis. It is frequently present at the onset of disease and it may even precede muscular manifestations of IIM. The most common presentation is a symmetrical, nonerosive polyarthritis affecting particularly the wrists, shoulders, and small joints of the hands. We have confirmed a strong association of arthritis with the presence of the anti-Jo1 antibody.

• Klíčová slova
• ARTHRITIS, AUTOANTIBODIES, IDIOPATHIC INFLAMMATORY MYOPATHIES,
• MeSH
• alely MeSH
• artritida epidemiologie   genetika   imunologie   MeSH
• autoprotilátky * MeSH
• dospělí MeSH
• genotyp MeSH
• HLA-DQ beta řetězec genetika   MeSH
• HLA-DRB1 řetězec genetika   MeSH
• komorbidita MeSH
• lidé středního věku MeSH
• lidé MeSH
• myozitida epidemiologie   genetika   imunologie   MeSH
• prevalence MeSH
• průřezové studie MeSH
• senioři MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Názvy látek
• autoprotilátky * MeSH
• HLA-DQ beta řetězec MeSH
• HLA-DQB1 antigen MeSH Prohlížeč
• HLA-DRB1 řetězec MeSH