Acne vulgaris Dotaz Zobrazit nápovědu
- Klíčová slova
- ACNE *, AZAGUANINE *, BORATES *,
- MeSH
- acne vulgaris * MeSH
- azaguanin * MeSH
- boritany * MeSH
- lidé MeSH
- masky * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- azaguanin * MeSH
- boritany * MeSH
An inevitable condition for the pharmacist is a basic knowledge of dermatological changes which are prominent in acne and solar impairment of the skin to be able to recommend in a qualified manner an effective and safe treatment to the patient. However, sufferers of the more serious forms of acne should always be referred to their general practitioner, or preferentially a dermatologist. Acne vulgaris is an androgen-induced disorder, but three major mechanisms for the development of the disease have been identified: hypertrophy of the sebaceous gland, hyperkatosis of the follicular epithelium, and proliferation of microbial flora, particularly Propionibacterium acnes. The basis of all lesions is the microcomedone which is developed into the ripe comedone. Inflammatory lesions are thought to be due to proliferation of P. acnes. In the selfmedication of common acne, benzoyl peroxide, which in a 5-10% lotion exerts antimicrobial and keratolytic properties, proved to be useful. Patients appreciate a lot its instant effect which is visible after just one day of treatment. Salicylic acid is another effective drug, which, when used on the long-term basis, has comedolytic properties; it reduces the number of microcomedones and counteracts plugging of the follicles. In addition, in healthy young women who take oral contraception, a triphasic combined oral preparations of contraceptives with newer progestins, notably with norgestimmate, which is practically free of androgenic effects, are recommended with advantage for the treatment of moderate acne vulgaris without any adverse effects. Solar impairment of the skin, the so-called solar ageing, is clinically indistinguishable from biological ageing. Changes connected with solar impairment appear mostly in the dermis, where solar elastosis develops, the skin gets drier and wrinkle formation appears. For the treatment, hydroxy acids are recommended, namely salicylic acid, which is very effective, because in combination with a suitable vehicle it produces desquamation or exfoliation. Desquamation is beneficial as it gives a youthful appearance to the skin.
- MeSH
- acne vulgaris farmakoterapie MeSH
- dermatologické látky terapeutické užití MeSH
- lidé MeSH
- stárnutí kůže * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- dermatologické látky MeSH
- Klíčová slova
- ACNE *,
- MeSH
- acne vulgaris * MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- acne vulgaris mikrobiologie MeSH
- Corynebacterium izolace a purifikace MeSH
- kultivační média MeSH
- lidé MeSH
- metody MeSH
- Staphylococcus izolace a purifikace MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- kultivační média MeSH
The authors administered to 20 patients with acne vulgaris (14 patients with the papulopustulous form of acne, 6 patients with the indurative or cystic form of acne) the preparation STAVA inj. After treatment they evaluated the therapeutic effect of the preparation and the state of immunity of the patient. Treatment failed in three patients with the cystic form where there was a severe deficiency of the cellular immunity component. In six patients, where the cellular immunity was deficient treatment was satisfactory and it was almost restored to normal after treatment. In 11 patients the authors recorded an excellent therapeutic effect already after three weeks' administration and after treatment they recorded complete recovery of cellular immunity. The authors recommend this immunomodulating treatment when other treatment is not effective or contraindicated. In the conclusion they emphasize that STAVA inj. are an excellent immunostimulating preparation when cellular immunity is deficient. The therapeutic effect is good and so is the tolerance; there are no side-reactions.
- MeSH
- acne vulgaris imunologie terapie MeSH
- adjuvancia imunologická terapeutické užití MeSH
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Názvy látek
- adjuvancia imunologická MeSH
[Topical effects of oxytetracycline in acne vulgaris]
- MeSH
- acne vulgaris farmakoterapie MeSH
- klinické zkoušky jako téma MeSH
- lidé MeSH
- oxytetracyklin aplikace a dávkování terapeutické užití MeSH
- placeba MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky kontrolované MeSH
- klinické zkoušky MeSH
- Názvy látek
- oxytetracyklin MeSH
- placeba MeSH
The present article gives a concise survey of contemporary opinions on acne vulgaris, its etiopathogenesis, clinical forms and laboratory diagnostics. In particular, the value of microbiological diagnostics and possibilities of local as well as general therapy are discussed. Moreover, our experience is described with vaccinotherapy to manage serious clinical forms and cases when current therapy fails.
- MeSH
- acne vulgaris mikrobiologie terapie MeSH
- bakteriální vakcíny terapeutické užití MeSH
- kůže mikrobiologie MeSH
- lidé MeSH
- Propionibacterium růst a vývoj MeSH
- Staphylococcus růst a vývoj MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- bakteriální vakcíny MeSH
- Klíčová slova
- ACNE *,
- MeSH
- acne vulgaris * MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- acne vulgaris imunologie MeSH
- antigeny bakteriální MeSH
- antigeny * MeSH
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- Propionibacterium acnes imunologie MeSH
- reakce antigenu s protilátkou MeSH
- Staphylococcus imunologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny bakteriální MeSH
- antigeny * MeSH
- MeSH
- acne vulgaris farmakoterapie MeSH
- aplikace lokální MeSH
- dospělí MeSH
- lidé MeSH
- tretinoin aplikace a dávkování terapeutické užití MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Názvy látek
- tretinoin MeSH