Indexing
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We demonstrate the capability of a novel Electron Backscatter Diffraction (EBSD) dictionary indexing (DI) approach by means of orientation mapping of a highly deformed graded microstructure in a shot peened Aluminium 7075-T651 alloy. A low microscope accelerating voltage was used to extract, for the first time from a bulk sample, statistically significant orientation information from a region close to a shot crater, showing both recrystallized nano-grains and heavily deformed grains. We show that the robust nature of the DI method allows for faster acquisition of lower quality patterns, limited only by the camera hardware, compared to the acquisition speed and pattern quality required for the conventional Hough indexing (HI) approach. The proposed method paves the way for the quantitative and accurate EBSD characterization of heavily deformed microstructures at a sub-micrometer length scale in cases where the current indexing techniques largely fail.
- Publikační typ
- časopisecké články MeSH
Deregulation of microRNA (miRNA) expression plays a critical role in the transition from a physiological to a pathological state. The accurate miRNA promoter identification in multiple cell types is a fundamental endeavor towards understanding and characterizing the underlying mechanisms of both physiological as well as pathological conditions. DIANA-miRGen v4 (www.microrna.gr/mirgenv4) provides cell type specific miRNA transcription start sites (TSSs) for over 1500 miRNAs retrieved from the analysis of >1000 cap analysis of gene expression (CAGE) samples corresponding to 133 tissues, cell lines and primary cells available in FANTOM repository. MiRNA TSS locations were associated with transcription factor binding site (TFBSs) annotation, for >280 TFs, derived from analyzing the majority of ENCODE ChIP-Seq datasets. For the first time, clusters of cell types having common miRNA TSSs are characterized and provided through a user friendly interface with multiple layers of customization. DIANA-miRGen v4 significantly improves our understanding of miRNA biogenesis regulation at the transcriptional level by providing a unique integration of high-quality annotations for hundreds of cell specific miRNA promoters with experimentally derived TFBSs.
- MeSH
- anotace sekvence MeSH
- buněčné linie MeSH
- databáze nukleových kyselin * MeSH
- genetická transkripce MeSH
- genom * MeSH
- internet MeSH
- lidé MeSH
- mikro RNA genetika metabolismus MeSH
- počátek transkripce MeSH
- primární buněčná kultura MeSH
- promotorové oblasti (genetika) * MeSH
- sekvence nukleotidů MeSH
- software * MeSH
- transkripční faktory genetika metabolismus MeSH
- vazba proteinů MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- mikro RNA MeSH
- transkripční faktory MeSH
Article deals with evaluation method of scientific works by means of Citation Indexes and Impact Factor which are produced by Institute for Scientific Information of Philadelphia. It criticizes criteria of the usage of Impact factor and way of research workers evaluation.
Article deals with evaluation method of scientific works by means of Citation Indexes and Impact Factor which are produced by Institute for Scientific Information of Philadelphia. It criticize criteria of the usage of Impact factor and way of research workers evaluation.
Article deals with evaluation method of scientific works by means of Citation Indexes and Impact Factor which are produced by Institute for Scientific Information of Philadelphia. It criticizes criteria of the usage of Impact factor and way of research workers evaluation.
- MeSH
- děrnoštítkové systémy * MeSH
- referování a indexace jako téma * MeSH
- zubní lékařství * MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- bibliografie jako téma MeSH
- informační služby * MeSH
- metody MeSH
- referování a indexace jako téma MeSH
- Publikační typ
- bibliografie MeSH
- časopisecké články MeSH
- Geografické názvy
- Spojené státy americké MeSH
- MeSH
- autorství MeSH
- psaní * MeSH
- referování a indexace jako téma * MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Československo MeSH
- MeSH
- nukleární lékařství metody trendy MeSH
- referování a indexace jako téma * MeSH
- společnosti lékařské organizace a řízení MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
