Neceliakální glutenová senzitivita Dotaz Zobrazit nápovědu
Non-celiac gluten sensitivity has recently been recognized by the scientific community as a part of gluten-related disorders, and is defined as a condition with gastrointestinal and/or extra-intestinal symptoms triggered by gluten ingestion in the absence of celiac disease and wheat allergy. Currently, there is no specific serological marker and non-celiac gluten sensitivity remains a diagnosis of exclusion: testing for celiac disease and wheat allergy must be negative, symptoms must improve with a gluten-free diet, and diagnosis must be confirmed by the gluten challenge. In this article, we discuss current knowledge of pathophysiology, clinical and epidemilogical spectrum, diagnosis, and treatment of NCGS.
- Klíčová slova
- celiac disease - FODMAPs - gluten-free diet - gluten-related disorders - irritable bowel syndrome - non-celiac gluten sensitivity - wheat allergy.,
- MeSH
- alergie na pšenici diagnóza terapie MeSH
- bezlepková dieta MeSH
- celiakie diagnóza terapie MeSH
- gluteny * MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- gluteny * MeSH
Non-celiac gluten/wheat sensitivity (NCG/WS) is a syndrome characterized by intestinal and extra-intestinal sym-ptoms elicited by gluten/wheat ingestion in the persons, who are not affected by celiac disease and wheat allergy. Due to the lack of established biomarkers, the diagnosis of NCG/WS is based on the clinical picture, and it is necessary to validate it in well-defined double-blind, placebo-controlled challenge (The Salerno Experts´ Criteria). In the article is discussed a current knowledge of NCG/WS in terms of pathogenesis, diagnosis and treatment. Key words: gluten - gluten-related disorders - non-celiac gluten/wheat sensitivity - wheat.
- Klíčová slova
- gluten - gluten-related disorders - non-celiac gluten/wheat sensitivity - wheat,
- MeSH
- alergie na pšenici * diagnóza farmakoterapie MeSH
- bezlepková dieta MeSH
- celiakie * diagnóza dietoterapie MeSH
- dvojitá slepá metoda MeSH
- gluteny MeSH
- lidé MeSH
- pšenice MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- gluteny MeSH
