equine Dotaz Zobrazit nápovědu
- Klíčová slova
- ENCEPHALOMYELITIS, EQUINE/case reports *,
- MeSH
- chorobopisy * MeSH
- distorze a distenze * MeSH
- encefalomyelitida koňská * MeSH
- encefalomyelitida * MeSH
- koně MeSH
- viry * MeSH
- západní koňská encefalomyelitida * MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
Twelve confirmed cases of equine granulocytic anaplasmosis (EGA) and five additional suspected cases, showing a compatible clinical history and specific IgG titres of 1280 or above, were recorded in the Czech Republic during the period 2002 to 2008. The diagnosis was based on clinical signs, the detection of Anaplasma phagocytophilum morulae in neutrophils in blood smears, serology and molecular methods. Pyrexia (39.8 to 41.3 degrees C), depression, partial or total anorexia, limb oedema and icterus were the most frequently observed clinical abnormalities. Haematological examination revealed thrombocytopenia in all the horses, and mild anaemia and leucopenia in five of them. Several horses showed high titres of specific antibodies immediately after onset of the disease, suggesting that they had previously been exposed to A phagocytophilum. Genotyping of the A phagocytophilum strains distinguished two genetic variants, with divergence in the sequence of the ank gene of the bacterium, circulating in the Czech Republic.
- MeSH
- Anaplasma phagocytophilum * genetika imunologie MeSH
- ehrlichióza epidemiologie mikrobiologie patologie veterinární MeSH
- genetická variace MeSH
- genotyp MeSH
- koně MeSH
- nemoci koní epidemiologie mikrobiologie patologie MeSH
- protilátky bakteriální krev MeSH
- roční období MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- protilátky bakteriální MeSH
- Klíčová slova
- ENCEPHALOMYELITIS, EQUINE/transmission *, TICKS *,
- MeSH
- Dermacentor * MeSH
- encefalomyelitida koňská přenos MeSH
- encefalomyelitida * MeSH
- hibernace * MeSH
- klíšťata * MeSH
- klíště * MeSH
- koně MeSH
- lidé MeSH
- rasové skupiny * MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Spojené státy americké MeSH
Equine herpesvirus type 1 was determined as the etiological cause of an abortion storm in Czechia in 2003 after the virus strain was isolated from aborted fetus and identified by serological means and by PCR technique. Cloning and sequencing of the glycoprotein D confirmed the identity of the isolates and showed molecular relationships to known EHV-1 strains. Comparison of glycoprotein D sequences with corresponding sequence of EHV-1 reference strains (Kentucky-A and Ab1) revealed high nucleotide homology. The Czech isolate of EHV-1 virus does not differ significantly from the Ab1 strain regarding the glycoprotein D gene and does not bear the frameshift in the 3' terminus which occurs in the Kentucky-A strain.
- MeSH
- DNA virů genetika MeSH
- druhová specificita MeSH
- herpesvirus 1 koní klasifikace genetika izolace a purifikace MeSH
- herpetické infekce epidemiologie veterinární virologie MeSH
- klonování DNA MeSH
- koně virologie MeSH
- molekulární sekvence - údaje MeSH
- nemoci koní epidemiologie virologie MeSH
- potrat u zvířat epidemiologie virologie MeSH
- proteiny virového obalu genetika MeSH
- sekvence nukleotidů MeSH
- sekvenční homologie nukleových kyselin MeSH
- těhotenství MeSH
- zvířata MeSH
- Check Tag
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- DNA virů MeSH
- glycoprotein D, Equid herpesvirus 1 MeSH Prohlížeč
- proteiny virového obalu MeSH
- MeSH
- DNA analýza MeSH
- encefalomyelitida koňská imunologie MeSH
- erytrocyty analýza MeSH
- kuřecí embryo MeSH
- mozaicismus * MeSH
- testy inhibice hemaglutinace MeSH
- viry imunologie MeSH
- zvířata MeSH
- Check Tag
- kuřecí embryo MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- DNA MeSH
- Klíčová slova
- ENCEPHALOMYELITIS, EQUINE/virus *, TICKS *, VIRUSES *,
- MeSH
- encefalomyelitida koňská * MeSH
- encefalomyelitida * MeSH
- klíšťata * MeSH
- koně MeSH
- savci * MeSH
- viry encefalitidy * MeSH
- viry * MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Slovenská republika MeSH
- Spojené státy americké MeSH
Atypical myopathy (AM) is a potentially fatal disease of grazing horses. It is reportedly caused by the ingestion of sycamore seeds containing toxic hypoglycin A. In order to study metabolic changes, serum and urine samples from nine horses with atypical myopathy and 12 control samples from clinically healthy horses were collected and then analysed using a high-performance liquid chromatography coupled with tandem mass spectrometry; serum metabolic profiles as the disease progressed were also studied. Metabolic data were evaluated using unsupervised and supervised multivariate analyses. Significant differences were demonstrated in the concentrations of various glycine conjugates and acylcarnitines (C2-C26). Moreover, the concentrations of purine and pyrimidine metabolites, vitamins and their degradation products (riboflavin, trigonelline, pyridoxate, pantothenate), and selected organic and amino acids (aspartate, leucine, 2-oxoglutarate, etc.) were altered in horses with AM. These results represent a global view of altered metabolism in horses with atypical myopathy.
- Klíčová slova
- Atypical myopathy, Horse, Hypoglycin A, Metabolomics, Multiple acyl-CoA dehydrogenase deficiency, Seasonal pasture myopathy,
- MeSH
- biochemická analýza krve veterinární MeSH
- koně MeSH
- metabolom * MeSH
- moč chemie MeSH
- nemoci koní krev metabolismus moč MeSH
- nemoci svalů krev metabolismus moč veterinární MeSH
- sérum chemie MeSH
- tandemová hmotnostní spektrometrie veterinární MeSH
- vysokoúčinná kapalinová chromatografie veterinární MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: To describe and report preliminary outcomes of a contralateral trans-nasal endoscopic laser fenestration of the conchae for endoscopic examination and treatment of paranasal sinuses in horses. STUDY DESIGN: Cadaveric experimental and prospective clinical study. ANIMALS: Normal cadaveric equine heads (n = 7) and equine patients (horses n = 7, donkey n = 1) diagnosed with sinusitis. METHODS: Ex vivo: a video-endoscope containing a diode laser fiber in the working canal was passed through the nostril and retroflexed in the nasopharynx toward the contralateral conchae. Ventral or dorsal conchae were fenestrated. Duration of surgery, laser energy, visualization quality, and feasibility of sinoscopy through the fenestrations were recorded. In vivo: sinus drainage, sinoscopy 24 hours postoperatively, stoma persistence, and clinical results after 3 months were evaluated in 8 patients. RESULTS: Fenestrations were performed in 8 dorsal conchae (6 cadavers, 2 patients), 10 ventral conchae (5 cadavers, 5 patients), and 1 dorsal conchal bulla (1 patient). Visualization was good in 6 patients and affected by bleeding in 2 patients. Drainage through the fenestrations was observed in all patients. Trans-nasal sinoscopy was possible in all cadavers and in 6 out of 8 patients. Masses inside the sinuses precluded sinoscopy in 2 patients. Stomata persisted until discharge of the patients (mean of 14 days). Clinical signs improved in 6/8 patients. CONCLUSION: The endoscopic approach reported here provides good visualization during the trans-endoscopic laser fenestration of the conchae. The fenestrations may allow a trans-nasal sinoscopic examination and treatment in selected cases of sinusitis in horses.
- MeSH
- endoskopie veterinární MeSH
- koně chirurgie MeSH
- lasery polovodičové * MeSH
- mrtvola MeSH
- nemoci koní chirurgie MeSH
- nosní dutina MeSH
- otologické chirurgické výkony přístrojové vybavení metody veterinární MeSH
- paranazální dutiny chirurgie MeSH
- prospektivní studie MeSH
- sinusitida chirurgie veterinární MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- klinické zkoušky MeSH
- MeSH
- chemické jevy MeSH
- chemie MeSH
- koně MeSH
- konjugované estrogeny (USP) analýza MeSH
- spektrofotometrie ultrafialová MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- konjugované estrogeny (USP) MeSH
- Klíčová slova
- TICKS *,
- MeSH
- encefalomyelitida koňská * MeSH
- klíšťata * MeSH
- Ricinus * MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Spojené státy americké MeSH