• Je něco špatně v tomto záznamu ?

Dicarboxylic acid esters as transdermal permeation enhancers: effects of chain number and geometric isomers

M Novotny, A Hrabalek, B Janusova, J Novotny, K Vavrova

. 2009 ; 19 (2) : 344-347.

Jazyk angličtina Země Velká Británie

Perzistentní odkaz   https://www.medvik.cz/link/bmc11006135
E-zdroje

NLK ScienceDirect (archiv) od 1993-01-01 do 2009-12-31

A series of transdermal permeation enhancers based on dicarboxylic acid esters was studied. Single-chain amphiphiles were markedly more effective than the double-chain ones. Monododecyl maleate, that is a cis derivative, was a more potent enhancer than its trans isomer, while the activity of succinates strongly depended on the donor vehicle. No difference between diastereoisomeric tartaric and meso-tartaric acid derivatives was found.

000      
01760naa 2200313 a 4500
001      
bmc11006135
003      
CZ-PrNML
005      
20121114125927.0
008      
110331s2009 xxk e eng||
009      
AR
040    __
$a ABA008 $b cze $c ABA008 $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxk
100    1_
$a Novotný, Michal $7 xx0130082
245    10
$a Dicarboxylic acid esters as transdermal permeation enhancers: effects of chain number and geometric isomers / $c M Novotny, A Hrabalek, B Janusova, J Novotny, K Vavrova
314    __
$a Centre for New Antivirals and Antineoplastics, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
520    9_
$a A series of transdermal permeation enhancers based on dicarboxylic acid esters was studied. Single-chain amphiphiles were markedly more effective than the double-chain ones. Monododecyl maleate, that is a cis derivative, was a more potent enhancer than its trans isomer, while the activity of succinates strongly depended on the donor vehicle. No difference between diastereoisomeric tartaric and meso-tartaric acid derivatives was found.
650    _2
$a kyseliny dikarboxylové $x farmakologie $x chemie $7 D003998
650    _2
$a estery $7 D004952
650    _2
$a isomerie $7 D007536
650    _2
$a kožní absorpce $x účinky léků $7 D012869
650    _2
$a financování organizované $7 D005381
700    1_
$a Hrabálek, Alexandr, $d 1956- $7 nlk19990073261
700    1_
$a Janůšová, Barbora. $7 xx0300539
700    1_
$a Novotný, Jakub. $7 _AN026261
700    1_
$a Vávrová, Kateřina $7 xx0118201
773    0_
$t Bioorganic & Medicinal Chemistry Letters $w MED00000770 $g Roč. 19, č. 2 (2009), s. 344-347
910    __
$a ABA008 $b x $y 2
990    __
$a 20110414100140 $b ABA008
991    __
$a 20121114125943 $b ABA008
999    __
$a ok $b bmc $g 833753 $s 698226
BAS    __
$a 3
BMC    __
$a 2009 $b 19 $c 2 $d 344-347 $m Bioorganic & medicinal chemistry letters $n Bioorg Med Chem Lett $x MED00000770
LZP    __
$a 2011-1B09/dkme

Najít záznam