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Renal denervation in the treatment of resistant arterial hypertension and other perspectives
M. Poloczek, P. Vysocanova, R. Miklik, I. Nykl, P. Kala
Language English Country Czech Republic
Document type Review
NLK
ROAD: Directory of Open Access Scholarly Resources
from 2006
- Keywords
- rezistentní hypertenze,
- MeSH
- Denervation utilization MeSH
- Hypertension therapy MeSH
- Clinical Trials as Topic MeSH
- Kidney innervation MeSH
- Humans MeSH
- Metabolic Syndrome MeSH
- Sympathectomy methods utilization MeSH
- Sympathetic Nervous System physiopathology MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Renal denervation (RDN) is a new perspective method for the treatment of resistant hypertension. Surgical sympathectomy has been considered as a possible treatment of hypertension for many years—long before the discovery of antihypertensive drugs. The selective percutaneous transcatheter application of radiofrequency energy in renal arteries to eliminate sympathetic nerve fibers has been used in human medicine since 2009. The recent boom of this method has been supported by published clinical studies showing efficacy of this new treatment modality. Nevertheless, RDN is still an experimental method to be used only in specialized research centers. In this review we will provide up-to-date information about the use of RND as a novel method for the treatment of hypertension as well as discuss potential perspectives of RND in the treatment of various medical conditions.
Literatura
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- $a Poloczek, Martin $7 xx0101387 $u Department of Internal Medicine and Cardiology, Masaryk University and University Hospital Brno, Jihlavska 20, Brno 62500, Czech Republic b Department of Cardiology, Podlesi Hospital, Trinec, Czech Republic
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- $a Renal denervation (RDN) is a new perspective method for the treatment of resistant hypertension. Surgical sympathectomy has been considered as a possible treatment of hypertension for many years—long before the discovery of antihypertensive drugs. The selective percutaneous transcatheter application of radiofrequency energy in renal arteries to eliminate sympathetic nerve fibers has been used in human medicine since 2009. The recent boom of this method has been supported by published clinical studies showing efficacy of this new treatment modality. Nevertheless, RDN is still an experimental method to be used only in specialized research centers. In this review we will provide up-to-date information about the use of RND as a novel method for the treatment of hypertension as well as discuss potential perspectives of RND in the treatment of various medical conditions.
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