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Optimizing and evaluating the biocompatibility of fiber composites with calcium phosphate additives
T. Suchý, K. Balík, Z. Sucharda, M. Sochor, M. Lapčíková, R. Sedláček,
Jazyk angličtina Země Rakousko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- apatity MeSH
- dimethylpolysiloxany MeSH
- fosforečnany vápenaté MeSH
- hydroxyapatit MeSH
- kosti a kostní tkáň chirurgie MeSH
- kostní náhrady chemie normy MeSH
- králíci MeSH
- krevní plazma MeSH
- lidé MeSH
- mikroskopie elektronová rastrovací MeSH
- mikrotechnologie MeSH
- nanostruktury MeSH
- nylony MeSH
- osteointegrace fyziologie MeSH
- polymery MeSH
- povrchové vlastnosti MeSH
- pružnost MeSH
- software MeSH
- testování materiálů metody MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Composite materials based on a polyamide fabric (aramid) and a polydymethylsiloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20, and 25 vol.% of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. We studied the effect of the additives on the biocompatibility of the composite. It appears that nano additives have a more favorable effect on mechanical properties than microparticles. 15 vol.% of nano hydroxyapatite additive is an optimum amount for final application of the composites as substitutes for bone tissue: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
Citace poskytuje Crossref.org
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- $a Composite materials based on a polyamide fabric (aramid) and a polydymethylsiloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20, and 25 vol.% of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. We studied the effect of the additives on the biocompatibility of the composite. It appears that nano additives have a more favorable effect on mechanical properties than microparticles. 15 vol.% of nano hydroxyapatite additive is an optimum amount for final application of the composites as substitutes for bone tissue: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
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