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Optimizing and evaluating the biocompatibility of fiber composites with calcium phosphate additives
T. Suchý, K. Balík, Z. Sucharda, M. Sochor, M. Lapčíková, R. Sedláček,
Language English Country Austria
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Apatites MeSH
- Dimethylpolysiloxanes MeSH
- Calcium Phosphates MeSH
- Durapatite MeSH
- Bone and Bones surgery MeSH
- Bone Substitutes chemistry standards MeSH
- Rabbits MeSH
- Plasma MeSH
- Humans MeSH
- Microscopy, Electron, Scanning MeSH
- Microtechnology MeSH
- Nanostructures MeSH
- Nylons MeSH
- Osseointegration physiology MeSH
- Polymers MeSH
- Surface Properties MeSH
- Elasticity MeSH
- Software MeSH
- Materials Testing methods MeSH
- Animals MeSH
- Check Tag
- Rabbits MeSH
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Composite materials based on a polyamide fabric (aramid) and a polydymethylsiloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20, and 25 vol.% of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. We studied the effect of the additives on the biocompatibility of the composite. It appears that nano additives have a more favorable effect on mechanical properties than microparticles. 15 vol.% of nano hydroxyapatite additive is an optimum amount for final application of the composites as substitutes for bone tissue: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
References provided by Crossref.org
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- $a Composite materials based on a polyamide fabric (aramid) and a polydymethylsiloxane (PDMS) matrix were designed for application in bone surgery. In order to increase the bioactivity, 2, 5, 10, 15, 20, and 25 vol.% of nano/micro hydroxyapatite (HA) and tricalcium phosphate (TCP) were added. We studied the effect of the additives on the biocompatibility of the composite. It appears that nano additives have a more favorable effect on mechanical properties than microparticles. 15 vol.% of nano hydroxyapatite additive is an optimum amount for final application of the composites as substitutes for bone tissue: in this case both the mechanical properties and the biological properties are optimized without distinct changes in the inner structure of the composite.
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