• Something wrong with this record ?

A Continuous Glucose Monitoring System (CGMS) - a promising approach for improving metabolic control in persons with type 1 Diabetes mellitus treated by insulin pumps

P. Mlcák, J. Fialová, K. Trnková, R. Chlup

. 2004 ; 148 (1) : 33-38.

Language English Country Czech Republic

Document type Journal Article, Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc13003847

This pilot study deals with the possibilities of a Continuous Glucose Monitoring System (CGMS, Minimed- Medtronic) to optimize insulin substitution. Ten persons with type 1 diabetes mellitus treated by means of an insulin pump entered the study and eight of them completed the protocol. CGMS was introduced for a period of 5 days. The standard dinner (60 g of carbohydrates) and overnight fasting were designed to ensure standard night conditions in all persons in the study while maintaining their usual daily eating routine, physical exercise and assessment of prandial insulin boluses. The only adaptation of basal rates of insulin pump was performed on day 3. Comparison of the mean plasma glucose concentration (0:00-24:00 hrs) between day 2 (before adaptation) and day 4 (following adaptation) was made. An independent comparison of the mean plasma glucose concentration between the night from day 2 till day 3 (22:00-6:00 hrs) and the night from day 4 till day 5 (22:00-6:00 hrs) was performed. The mean plasma glucose investigated by means of CGMS improved in the 24-hour period in 5 out of 8 persons and in the night fasting period (22:00 to 6 hrs) in 6 out of 8 persons. The CGMS is a useful means for assessment of the effectiveness of basal rate and prandial insulin doses in persons with type 1 diabetes treated by means of an insulin pump. However, further studies are necessary to improve the algorithm for insulin substitution.

References provided by Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc13003847
003      
CZ-PrNML
005      
20130321185412.0
007      
ta
008      
130128s2004 xr do f 000 0|eng||
009      
AR
024    7_
$a 10.5507/bp.2004.005 $2 doi
035    __
$a (PubMed)15523543
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xr
100    1_
$a Mlčák, Petr $7 xx0127959 $u Institute of Physiology, Faculty of Medicine, Palacký University, Olomouc, Czech Republic
245    12
$a A Continuous Glucose Monitoring System (CGMS) - a promising approach for improving metabolic control in persons with type 1 Diabetes mellitus treated by insulin pumps / $c P. Mlcák, J. Fialová, K. Trnková, R. Chlup
520    9_
$a This pilot study deals with the possibilities of a Continuous Glucose Monitoring System (CGMS, Minimed- Medtronic) to optimize insulin substitution. Ten persons with type 1 diabetes mellitus treated by means of an insulin pump entered the study and eight of them completed the protocol. CGMS was introduced for a period of 5 days. The standard dinner (60 g of carbohydrates) and overnight fasting were designed to ensure standard night conditions in all persons in the study while maintaining their usual daily eating routine, physical exercise and assessment of prandial insulin boluses. The only adaptation of basal rates of insulin pump was performed on day 3. Comparison of the mean plasma glucose concentration (0:00-24:00 hrs) between day 2 (before adaptation) and day 4 (following adaptation) was made. An independent comparison of the mean plasma glucose concentration between the night from day 2 till day 3 (22:00-6:00 hrs) and the night from day 4 till day 5 (22:00-6:00 hrs) was performed. The mean plasma glucose investigated by means of CGMS improved in the 24-hour period in 5 out of 8 persons and in the night fasting period (22:00 to 6 hrs) in 6 out of 8 persons. The CGMS is a useful means for assessment of the effectiveness of basal rate and prandial insulin doses in persons with type 1 diabetes treated by means of an insulin pump. However, further studies are necessary to improve the algorithm for insulin substitution.
650    _2
$a dospělí $7 D000328
650    _2
$a krevní glukóza $x analýza $7 D001786
650    _2
$a diabetes mellitus 1. typu $x krev $x farmakoterapie $7 D003922
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a lidé $7 D006801
650    _2
$a hypoglykemika $x aplikace a dávkování $7 D007004
650    _2
$a inzulin $x aplikace a dávkování $7 D007328
650    _2
$a inzulinové infuzní systémy $7 D007332
650    _2
$a mužské pohlaví $7 D008297
650    _2
$a lidé středního věku $7 D008875
650    _2
$a ambulantní monitorování $7 D018670
655    _2
$a časopisecké články $7 D016428
655    _2
$a práce podpořená grantem $7 D013485
700    1_
$a Fialová, Jana. $7 _AN071264 $u Institute of Physiology, Faculty of Medicine, Palacký University, Olomouc, Czech Republic
700    1_
$a Trnková, Kateřina. $7 _AN071265 $u Institute of Physiology, Faculty of Medicine, Palacký University, Olomouc, Czech Republic
700    1_
$a Chlup, Rudolf, $d 1947- $7 jn20001031001 $u Institute of Physiology, Faculty of Medicine, Palacký University, Olomouc, Czech Republic; 2nd Department of Medicine, Teaching Hospital & Faculty of Medicine, Palacky University, I. P. Pavlova 6, 775 00 Olomouc
773    0_
$w MED00012606 $t Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic $x 1213-8118 $g Roč. 148, č. 1 (2004), s. 33-38
910    __
$a ABA008 $b A 1502 $c sign $y 3 $z 0
990    __
$a 20130128 $b ABA008
991    __
$a 20130321185635 $b ABA008
999    __
$a ok $b bmc $g 966500 $s 802042
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2004 $b 148 $c 1 $d 33-38 $i 1213-8118 $m Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic $n Biomed. Pap. Fac. Med. Palacký Univ. Olomouc Czech Repub. (Print) $x MED00012606
LZP    __
$b NLK138 $a Pubmed-20130128

Find record

Citation metrics

Archiving options