-
Je něco špatně v tomto záznamu ?
Mitochondrial changes in adenocarcinoma of the pancreas
R. Novotný, J. Ehrmann, I. Tozzi di Angelo, V. Procházka, D. Klos, M. Loveček, J. Kysučan, R. Havlík,
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- biopsie MeSH
- duktální karcinom slinivky břišní ultrastruktura MeSH
- elektronová mikroskopie MeSH
- endosonografie MeSH
- lidé MeSH
- mitochondrie ultrastruktura MeSH
- nádory slinivky břišní ultrastruktura MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The aim of our study was to analyse the mitochondrial ultrastructure in primary ductal adenocarcinomas of the pancreas and to compare it with normal pancreatic cells. 52 samples of adenocarcinoma of the pancreas obtained by surgical resection or by endosonographic biopsy were examined. Compared to normal mitochondrial ultrastructure in non-tumorous cells, the mitochondria in cancer cells had a dense matrix and condensed configuration or with lucent-swelling matrix associated with disarrangement and distortion of cristae and partial or total cristolysis. Functionally, these structural alterations presume the presence of hypoxia-tolerant and hypoxia-sensitive cancer cells.
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc14040759
- 003
- CZ-PrNML
- 005
- 20200812082008.0
- 007
- ta
- 008
- 140107s2013 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3109/01913123.2013.788306 $2 doi
- 035 __
- $a (PubMed)23650995
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Novotný, Radko
- 245 10
- $a Mitochondrial changes in adenocarcinoma of the pancreas / $c R. Novotný, J. Ehrmann, I. Tozzi di Angelo, V. Procházka, D. Klos, M. Loveček, J. Kysučan, R. Havlík,
- 520 9_
- $a The aim of our study was to analyse the mitochondrial ultrastructure in primary ductal adenocarcinomas of the pancreas and to compare it with normal pancreatic cells. 52 samples of adenocarcinoma of the pancreas obtained by surgical resection or by endosonographic biopsy were examined. Compared to normal mitochondrial ultrastructure in non-tumorous cells, the mitochondria in cancer cells had a dense matrix and condensed configuration or with lucent-swelling matrix associated with disarrangement and distortion of cristae and partial or total cristolysis. Functionally, these structural alterations presume the presence of hypoxia-tolerant and hypoxia-sensitive cancer cells.
- 650 _2
- $a biopsie $7 D001706
- 650 _2
- $a duktální karcinom slinivky břišní $x ultrastruktura $7 D021441
- 650 _2
- $a endosonografie $7 D019160
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a elektronová mikroskopie $7 D008854
- 650 _2
- $a mitochondrie $x ultrastruktura $7 D008928
- 650 _2
- $a nádory slinivky břišní $x ultrastruktura $7 D010190
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Ehrmann, Jiří $u -
- 700 1_
- $a Tozzi di Angelo, Igor, $d 1963- $u - $7 xx0096668
- 700 1_
- $a Procházka, Vlastimil $u -
- 700 1_
- $a Klos, Dušan $u -
- 700 1_
- $a Loveček, Martin $u -
- 700 1_
- $a Kysučan, Jiří $u -
- 700 1_
- $a Havlík, Roman $u -
- 773 0_
- $w MED00004603 $t Ultrastructural pathology $x 1521-0758 $g Roč. 37, č. 3 (2013), s. 227-31
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/23650995 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20140107 $b ABA008
- 991 __
- $a 20200812082005 $b ABA008
- 999 __
- $a ok $b bmc $g 1005155 $s 839271
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2013 $b 37 $c 3 $d 227-31 $i 1521-0758 $m Ultrastructural pathology $n Ultrastruct Pathol $x MED00004603
- LZP __
- $a Pubmed-20140107
