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Prediction of compartment syndrome based on analysis of biochemical parameters
P. Mitas, M. Vejrazka, J. Hruby, R. Spunda, O. Pecha, J. Lindner, M. Spacek,
Jazyk angličtina Země Nizozemsko
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- akutní nemoc MeSH
- biologické markery krev MeSH
- časové faktory MeSH
- embolektomie škodlivé účinky MeSH
- embolie diagnóza chirurgie MeSH
- ischemie diagnóza chirurgie MeSH
- kompartment syndrom krev diagnóza etiologie chirurgie MeSH
- kyselina mléčná krev MeSH
- lidé středního věku MeSH
- lidé MeSH
- prediktivní hodnota testů MeSH
- prognóza MeSH
- prospektivní studie MeSH
- rizikové faktory MeSH
- senioři MeSH
- vena femoralis MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: The possibility of predicting severe compartment syndrome using simple biochemical parameters was evaluated in a single-center study of 55 patients who presented with acute femoral embolism and who were treated with open surgical embolectomy. METHODS: Parameters related to tissue damage and oxidative metabolism (i.e., lactate, bilirubin, myoglobin, uric acid, glucose, and fibrinogen) were monitored in ipsilateral femoral vein blood. RESULTS: Several statistically significant predictors of relevant compartment syndrome after surgical reperfusion were found, including lactate, uric acid, transcutaneous oxygen pressure, bilirubin, intrafascial pressure, and serum myoglobin. Glycemia and serum albumin did not significantly change over time. CONCLUSIONS: The lactate concentration in femoral vein blood sampled during surgical embolectomy can be used for the stratification of additional postoperative risk of clinically significant compartment syndrome complicating reperfusion after acute embolism of the femoral artery.
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- $a Mitas, Petr $u 2nd Department of Surgery, Department of Cardiovascular Surgery, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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- $a Prediction of compartment syndrome based on analysis of biochemical parameters / $c P. Mitas, M. Vejrazka, J. Hruby, R. Spunda, O. Pecha, J. Lindner, M. Spacek,
- 520 9_
- $a BACKGROUND: The possibility of predicting severe compartment syndrome using simple biochemical parameters was evaluated in a single-center study of 55 patients who presented with acute femoral embolism and who were treated with open surgical embolectomy. METHODS: Parameters related to tissue damage and oxidative metabolism (i.e., lactate, bilirubin, myoglobin, uric acid, glucose, and fibrinogen) were monitored in ipsilateral femoral vein blood. RESULTS: Several statistically significant predictors of relevant compartment syndrome after surgical reperfusion were found, including lactate, uric acid, transcutaneous oxygen pressure, bilirubin, intrafascial pressure, and serum myoglobin. Glycemia and serum albumin did not significantly change over time. CONCLUSIONS: The lactate concentration in femoral vein blood sampled during surgical embolectomy can be used for the stratification of additional postoperative risk of clinically significant compartment syndrome complicating reperfusion after acute embolism of the femoral artery.
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- $a Vejrazka, Martin $u Institute of Medical Biochemistry, First Faculty of Medicine, Charles University, Prague, Czech Republic.
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- $a Hruby, Jan $u 2nd Department of Surgery, Department of Cardiovascular Surgery, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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- $a Spunda, Rudolf $u 2nd Department of Surgery, Department of Cardiovascular Surgery, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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- $a Pecha, Ondrej $u Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University, Prague, Czech Republic.
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- $a Lindner, Jaroslav $u 2nd Department of Surgery, Department of Cardiovascular Surgery, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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- $a Spacek, Miroslav $u 2nd Department of Surgery, Department of Cardiovascular Surgery, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic. Electronic address: mirekspacek@seznam.cz.
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- $w MED00005646 $t Annals of vascular surgery $x 1615-5947 $g Roč. 28, č. 1 (2014), s. 170-7
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