-
Something wrong with this record ?
Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking
E. Bilkova, J. Forstova, L. Abrahamyan,
Language English Country Switzerland
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
NLK
Directory of Open Access Journals
from 2009
Free Medical Journals
from 2009
PubMed Central
from 2009
Europe PubMed Central
from 2009
ProQuest Central
from 2009-01-01
Open Access Digital Library
from 2009-01-01
Open Access Digital Library
from 2009-01-01
Health & Medicine (ProQuest)
from 2009-01-01
ROAD: Directory of Open Access Scholarly Resources
from 2009
PubMed
25055856
DOI
10.3390/v6072899
Knihovny.cz E-resources
- MeSH
- Adenoviridae physiology MeSH
- Cell Membrane metabolism virology MeSH
- Cell Nucleus metabolism virology MeSH
- Endosomes metabolism virology MeSH
- Eukaryotic Cells metabolism virology MeSH
- Host-Pathogen Interactions MeSH
- Virus Internalization * MeSH
- Humans MeSH
- Papillomaviridae physiology MeSH
- Parvoviridae physiology MeSH
- Polyomaviridae physiology MeSH
- Virus Replication MeSH
- Protein Transport MeSH
- Protein Binding MeSH
- Capsid Proteins chemistry metabolism MeSH
- Receptors, Virus metabolism MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment. Most of DNA viruses have to reach the nucleus to replicate. The capsid proteins involved in transmembrane penetration are exposed or released during endosomal trafficking of the virus. Subsequently, the conserved domains of capsid proteins interact with cellular membranes and ensure their efficient permeabilization. This review summarizes our current knowledge concerning the role of capsid proteins of small non-enveloped DNA viruses in intracellular membrane perturbation in the early stages of infection.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc15014128
- 003
- CZ-PrNML
- 005
- 20150429122216.0
- 007
- ta
- 008
- 150420s2014 sz f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.3390/v6072899 $2 doi
- 035 __
- $a (PubMed)25055856
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a sz
- 100 1_
- $a Bilkova, Eva $u Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, Vinicna 5, 12844, Prague 2, Czech Republic. bilkove@natur.cuni.cz.
- 245 10
- $a Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking / $c E. Bilkova, J. Forstova, L. Abrahamyan,
- 520 9_
- $a To get access to the replication site, small non-enveloped DNA viruses have to cross the cell membrane using a limited number of capsid proteins, which also protect the viral genome in the extracellular environment. Most of DNA viruses have to reach the nucleus to replicate. The capsid proteins involved in transmembrane penetration are exposed or released during endosomal trafficking of the virus. Subsequently, the conserved domains of capsid proteins interact with cellular membranes and ensure their efficient permeabilization. This review summarizes our current knowledge concerning the role of capsid proteins of small non-enveloped DNA viruses in intracellular membrane perturbation in the early stages of infection.
- 650 _2
- $a Adenoviridae $x fyziologie $7 D000256
- 650 _2
- $a virové plášťové proteiny $x chemie $x metabolismus $7 D036022
- 650 _2
- $a buněčná membrána $x metabolismus $x virologie $7 D002462
- 650 _2
- $a buněčné jádro $x metabolismus $x virologie $7 D002467
- 650 _2
- $a endozomy $x metabolismus $x virologie $7 D011992
- 650 _2
- $a eukaryotické buňky $x metabolismus $x virologie $7 D005057
- 650 _2
- $a interakce hostitele a patogenu $7 D054884
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a Papillomaviridae $x fyziologie $7 D027383
- 650 _2
- $a Parvoviridae $x fyziologie $7 D010321
- 650 _2
- $a Polyomaviridae $x fyziologie $7 D027382
- 650 _2
- $a vazba proteinů $7 D011485
- 650 _2
- $a transport proteinů $7 D021381
- 650 _2
- $a virové receptory $x metabolismus $7 D011991
- 650 12
- $a internalizace viru $7 D053586
- 650 _2
- $a replikace viru $7 D014779
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 655 _2
- $a přehledy $7 D016454
- 700 1_
- $a Forstova, Jitka $u Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, Vinicna 5, 12844, Prague 2, Czech Republic. jitka.forstova@natur.cuni.cz.
- 700 1_
- $a Abrahamyan, Levon $u Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, Vinicna 5, 12844, Prague 2, Czech Republic. levon.abrahamyan@natur.cuni.cz. $7 gn_A_00000750
- 773 0_
- $w MED00177099 $t Viruses $x 1999-4915 $g Roč. 6, č. 7 (2014), s. 2899-937
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/25055856 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20150420 $b ABA008
- 991 __
- $a 20150429122520 $b ABA008
- 999 __
- $a ok $b bmc $g 1071709 $s 897006
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2014 $b 6 $c 7 $d 2899-937 $i 1999-4915 $m Viruses $n Viruses $x MED00177099
- LZP __
- $a Pubmed-20150420
