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Lieky s mechanizmom pulzného uvoľňovania
[Pulsatile drug delivery systems]

Dana Sabadková, Aleš Franc, Jan Muselík, David Neumann, David Vetchý

. 2015 ; 109 (5) : 353-359.

Language Slovak Country Czech Republic

Document type Research Support, Non-U.S. Gov't

Persistent link   https://www.medvik.cz/link/bmc15024580

Grant support
NT14479 MZ0 CEP Register

This review is focused on the basic principles of the delivery systems with a pulsatile release pattern. Such systems are designed according to the circadian rhythm of the body. Time-controlled, stimuli-induced and externally regulated pulsatile drug delivery systems are recognized. The drug release of time-controlled systems occurs after a predefined time lag. Stimuli-induced systems release the drug as a reaction to changeable conditions in the body (pH, glucose level). The drug release of externally regulated systems is controlled via external stimulus (magnetism, ultrasound). Pulsatile drug delivery systems rank among modern dosage forms which provide many therapeutic benefits.

Pulsatile drug delivery systems

Bibliography, etc.

Literatura

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