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Sarcopenia: monitoring, molecular mechanisms, and physical intervention
A. Zembroń-Łacny, W. Dziubek, Ł. Rogowski, E. Skorupka, G. Dąbrowska
Language English Country Czech Republic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
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- MeSH
- Muscle, Skeletal metabolism pathology MeSH
- Humans MeSH
- Monitoring, Physiologic MeSH
- Resistance Training MeSH
- Sarcopenia diagnosis metabolism pathology rehabilitation MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Muscle Strength MeSH
- Exercise Therapy * MeSH
- Vibration MeSH
- Check Tag
- Humans MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
According to European Working Group on Sarcopenia in Older People (EWGSOP) sarcopenia includes both a loss of muscle strength and a decline in functional quality in addition to the loss of muscle protein mass. In order to develop strategies to prevent and treat sarcopenia, the risk factors and causes of sarcopenia must be identified. Age-related muscle loss is characterized by the contribution of multiple factors, and there is growing evidence for a prominent role of low-grade chronic inflammation in sarcopenia. The elderly who are less physically active are more likely to have lower skeletal muscle mass and strength and are at increased risk of developing sarcopenia. Resistance training added to aerobic exercise or high-intensity interval training promote numerous changes in skeletal muscle, many of which may help to prevent or reverse sarcopenia. In this review, we provided current information on definition and monitoring, molecular mechanisms, and physical intervention to counteract sarcopenia.
Department of Physical Education University of Zielona Gora Poland
Department of Physical Education University of Zielona Gora Zielona Gora Poland
References provided by Crossref.org
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