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Hornhautvernetzung beim Keratokonus: "Epi-off" oder "Epi-on" [Cross-Linking in Keratoconus: "Epi-off" or "Epi-on"?]

F. Raiskup, V. Veliká, M. Veselá, E. Spörl,

. 2015 ; 232 (12) : 1392-6. [pub] 20151217

Language German Country Germany

Document type English Abstract, Journal Article, Review

Corneal cross-linking can halt the progression of keratoconus, but what is the best approach for treatment? There are a number of treatment options for keratoconus, but only corneal cross-linking (CXL) appears to halt the progression of the disease. To guarantee effective cross-linking, CXL treatment involves removal of the corneal epithelium prior to riboflavin application and ultraviolet light illumination - "epi-off" CXL. Several methods of "epi-on" (transepithelial) CXL have been proposed, such as keeping the corneal epithelium intact which should be less painful and help avoid other CXL-associated adverse events. The evidence so far is that epi-off CXL remains the most effective method of strengthening the cornea and slowing keratoconus progression - but transepithelial methods are gaining ground.

Cross-Linking in Keratoconus: "Epi-off" or "Epi-on"?

References provided by Crossref.org

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