Hornhautvernetzung beim Keratokonus: "Epi-off" oder "Epi-on"?
[Cross-Linking in Keratoconus: "Epi-off" or "Epi-on"?]
Language German Country Germany Media print-electronic
Document type English Abstract, Journal Article, Review
- MeSH
- Photochemotherapy methods MeSH
- Photosensitizing Agents administration & dosage MeSH
- Keratoconus pathology therapy MeSH
- Combined Modality Therapy methods MeSH
- Humans MeSH
- Evidence-Based Medicine MeSH
- Cross-Linking Reagents administration & dosage MeSH
- Riboflavin administration & dosage MeSH
- Epithelium, Corneal surgery MeSH
- Ultraviolet Therapy methods MeSH
- Treatment Outcome MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Photosensitizing Agents MeSH
- Cross-Linking Reagents MeSH
- Riboflavin MeSH
Corneal cross-linking can halt the progression of keratoconus, but what is the best approach for treatment? There are a number of treatment options for keratoconus, but only corneal cross-linking (CXL) appears to halt the progression of the disease. To guarantee effective cross-linking, CXL treatment involves removal of the corneal epithelium prior to riboflavin application and ultraviolet light illumination - "epi-off" CXL. Several methods of "epi-on" (transepithelial) CXL have been proposed, such as keeping the corneal epithelium intact which should be less painful and help avoid other CXL-associated adverse events. The evidence so far is that epi-off CXL remains the most effective method of strengthening the cornea and slowing keratoconus progression - but transepithelial methods are gaining ground.
Klinik für Augenheilkunde Universitätsklinikum Carl Gustav Carus Dresden
Klinik für Augenheilkunde Universitätsklinikum Hradec Králové Tschechische Republik
References provided by Crossref.org
