-
Je něco špatně v tomto záznamu ?
Deagglomeration and characterization of detonation nanodiamonds for biomedical applications
Seidy Pedroso-Santana, Andrei Sarabia-Saínz, Noralvis Fleitas-Salazar, Karla Santacruz-Gómez, Monica Acosta-Elías, Martin Pedroza-Montero, Raul Riera
Jazyk angličtina Země Česko
Typ dokumentu práce podpořená grantem
- MeSH
- biokompatibilní materiály MeSH
- krevní buňky cytologie fyziologie MeSH
- nanodiamanty * normy MeSH
- Ramanova spektroskopie metody MeSH
- spektroskopie infračervená s Fourierovou transformací metody MeSH
- testování materiálů MeSH
- ultrazvuk metody přístrojové vybavení MeSH
- velikost částic MeSH
- Publikační typ
- práce podpořená grantem MeSH
Detonation nanodiamonds (DNDs) are usually small particles of 4–5 nm, but in aqueous suspension, DNDs form agglomerates in sizes larger than 1 μm. We propose the use of Bead Assisted Sonic Disintegration and a carboxylation procedure, to reduce DNDs aggregates sizes to approximately 100 nm. High cost zirconium beads have been substituted by silica beads synthetized in our laboratory and less-time consuming conditions were standardized. Techniques as Dynamic Light Scattering (DLS), Fourier Transform InfraRed Spectroscopy (FTIR), Transmission Electron Microscopy (TEM) and X-ray Photoelectron Spectroscopy (XPS), have been used to characterize the resulting diamond nanoparticles. While the incubation of Red Blood Cells with partially disaggregated DNDs was used to study whether these nanodiamonds impact in a living system. Our results show the absence of a negative effect in cell viability as well as no differences between Raman spectra of hemoglobin (Hb), from control and cell + DNDs conditions.
Citace poskytuje Crossref.org
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc17019230
- 003
- CZ-PrNML
- 005
- 20171102105148.0
- 007
- ta
- 008
- 170606s2017 xr ad f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1016/j.jab.2016.09.003 $2 doi
- 040 __
- $a ABA008 $d ABA008 $e AACR2 $b cze
- 041 0_
- $a eng
- 044 __
- $a xr
- 100 1_
- $a Pedroso-Santana, Seidy $u Departamento de Investigación en Física, Universidad de Sonora, Apartado postal 5-088, Hermosillo, C.P. 83190, Mexico
- 245 10
- $a Deagglomeration and characterization of detonation nanodiamonds for biomedical applications / $c Seidy Pedroso-Santana, Andrei Sarabia-Saínz, Noralvis Fleitas-Salazar, Karla Santacruz-Gómez, Monica Acosta-Elías, Martin Pedroza-Montero, Raul Riera
- 504 __
- $a Literatura
- 520 9_
- $a Detonation nanodiamonds (DNDs) are usually small particles of 4–5 nm, but in aqueous suspension, DNDs form agglomerates in sizes larger than 1 μm. We propose the use of Bead Assisted Sonic Disintegration and a carboxylation procedure, to reduce DNDs aggregates sizes to approximately 100 nm. High cost zirconium beads have been substituted by silica beads synthetized in our laboratory and less-time consuming conditions were standardized. Techniques as Dynamic Light Scattering (DLS), Fourier Transform InfraRed Spectroscopy (FTIR), Transmission Electron Microscopy (TEM) and X-ray Photoelectron Spectroscopy (XPS), have been used to characterize the resulting diamond nanoparticles. While the incubation of Red Blood Cells with partially disaggregated DNDs was used to study whether these nanodiamonds impact in a living system. Our results show the absence of a negative effect in cell viability as well as no differences between Raman spectra of hemoglobin (Hb), from control and cell + DNDs conditions.
- 650 12
- $a nanodiamanty $x normy $7 D058612
- 650 _2
- $a velikost částic $7 D010316
- 650 _2
- $a ultrazvuk $x metody $x přístrojové vybavení $7 D014465
- 650 _2
- $a spektroskopie infračervená s Fourierovou transformací $x metody $7 D017550
- 650 _2
- $a biokompatibilní materiály $7 D001672
- 650 _2
- $a testování materiálů $7 D008422
- 650 _2
- $a krevní buňky $x cytologie $x fyziologie $7 D001773
- 650 _2
- $a Ramanova spektroskopie $x metody $7 D013059
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Sarabia-Saínz, Andrei $u Departamento de Investigación en Física, Universidad de Sonora, Apartado postal 5-088, Hermosillo, C.P. 83190, Mexico
- 700 1_
- $a Fleitas-Salazar, Noralvis $u Departamento de Investigación en Física, Universidad de Sonora, Apartado postal 5-088, Hermosillo, C.P. 83190, Mexico
- 700 1_
- $a Santacruz-Gómez, Karla $u Departamento de Física, Universidad de Sonora, Hermosillo, Apartado postal 1626, C.P. 83000, Mexico
- 700 1_
- $a Acosta-Elías, Monica $u Departamento de Física, Universidad de Sonora, Hermosillo, Apartado postal 1626, C.P. 83000, Mexico $7 gn_A_00001038
- 700 1_
- $a Pedroza-Montero, Martin $u Departamento de Investigación en Física, Universidad de Sonora, Apartado postal 5-088, Hermosillo, C.P. 83190, Mexico
- 700 1_
- $a Riera, Raul $u Departamento de Investigación en Física, Universidad de Sonora, Apartado postal 5-088, Hermosillo, C.P. 83190, Mexico
- 773 0_
- $t Journal of applied biomedicine $x 1214-021X $g Roč. 15, č. 1 (2017), s. 15-21 $w MED00012667
- 856 41
- $u https://jab.zsf.jcu.cz/pdfs/jab/2017/01/03.pdf $y plný text volně přístupný
- 910 __
- $a ABA008 $b B 2301 $c 1249 $y 4 $z 0
- 990 __
- $a 20150522215938 $b ABA008
- 991 __
- $a 20171102105232 $b ABA008
- 999 __
- $a ok $b bmc $g 1231780 $s 980086
- BAS __
- $a 3
- BMC __
- $a 2017 $b 15 $c 1 $d 15-21 $i 1214-021X $m Journal of Applied Biomedicine $x MED00012667
- LZP __
- $c NLK125 $d 20171102 $a NLK 2017-21/dk
