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Polymorphisms of the receptor for advanced glycation end products and glyoxalase I and long-term outcome in patients with breast cancer
P. Tesarova, T. Zima, AA. Kubena, M. Kalousova,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články
NLK
Directory of Open Access Journals
od 2017
ProQuest Central
od 2017-01-01 do 2018-06-30
Health & Medicine (ProQuest)
od 2017-01-01 do 2018-06-30
Public Health Database (ProQuest)
od 2017-01-01 do 2018-06-30
ROAD: Directory of Open Access Scholarly Resources
od 1987
PubMed
28695773
DOI
10.1177/1010428317702902
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- jednonukleotidový polymorfismus MeSH
- Kaplanův-Meierův odhad MeSH
- laktoylglutathionlyasa genetika MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory prsu genetika mortalita patologie MeSH
- receptor pro konečné produkty pokročilé glykace genetika MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer. Potential relation between soluble forms of receptor for advanced glycation end products (sRAGE), receptor for advanced glycation end products, glyoxalase I polymorphisms, and long-term outcome (median follow-up of 10.3 years) was studied in 116 patients with breast cancer. Gly82Ser and 2184 A/G RAGE polymorphisms were related to the mortality due to the breast cancer and -419 A/C glyoxalase I polymorphism was related to the overall mortality of the patients suggesting their role not only in the risk of breast cancer but also in the outcome of patients with breast cancer.
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- $a Tesarova, Petra $u 1 Department of Oncology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
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- $a Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer. Potential relation between soluble forms of receptor for advanced glycation end products (sRAGE), receptor for advanced glycation end products, glyoxalase I polymorphisms, and long-term outcome (median follow-up of 10.3 years) was studied in 116 patients with breast cancer. Gly82Ser and 2184 A/G RAGE polymorphisms were related to the mortality due to the breast cancer and -419 A/C glyoxalase I polymorphism was related to the overall mortality of the patients suggesting their role not only in the risk of breast cancer but also in the outcome of patients with breast cancer.
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