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Polymorphisms of the receptor for advanced glycation end products and glyoxalase I and long-term outcome in patients with breast cancer
P. Tesarova, T. Zima, AA. Kubena, M. Kalousova,
Language English Country United States
Document type Journal Article
NLK
Directory of Open Access Journals
from 2017
ProQuest Central
from 2017-01-01 to 2018-06-30
Health & Medicine (ProQuest)
from 2017-01-01 to 2018-06-30
Public Health Database (ProQuest)
from 2017-01-01 to 2018-06-30
ROAD: Directory of Open Access Scholarly Resources
from 1987
- MeSH
- Adult MeSH
- Polymorphism, Single Nucleotide MeSH
- Kaplan-Meier Estimate MeSH
- Lactoylglutathione Lyase genetics MeSH
- Middle Aged MeSH
- Humans MeSH
- Breast Neoplasms genetics mortality pathology MeSH
- Receptor for Advanced Glycation End Products genetics MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
Receptor for advanced glycation end products and glyoxalase I metabolizing advanced glycation end product precursors may play important role in the pathogenesis and progression of cancer. Potential relation between soluble forms of receptor for advanced glycation end products (sRAGE), receptor for advanced glycation end products, glyoxalase I polymorphisms, and long-term outcome (median follow-up of 10.3 years) was studied in 116 patients with breast cancer. Gly82Ser and 2184 A/G RAGE polymorphisms were related to the mortality due to the breast cancer and -419 A/C glyoxalase I polymorphism was related to the overall mortality of the patients suggesting their role not only in the risk of breast cancer but also in the outcome of patients with breast cancer.
References provided by Crossref.org
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