• Je něco špatně v tomto záznamu ?

Aligned nanofibres made of poly(3-hydroxybutyrate) grafted to hyaluronan for potential healthcare applications

G. Huerta-Ángeles, K. Knotková, P. Knotek, O. Židek, M. Brandejsová, M. Pokorný, H. Vagnerová, I. Roy, V. Velebný,

. 2018 ; 29 (3) : 32. [pub] 20180315

Jazyk angličtina Země Spojené státy americké

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc18033235

In this work, a hybrid copolymer consisting of poly(3-hydroxybutyrate) grafted to hyaluronic acid (HA) was synthesised and characterised. Once formed, the P(3HB)-g-HA copolymer was soluble in water allowing a green electrospinning process. The diameters of nanofibres can be tailored by simply varying the Mw of polymer. The optimization of the process allowed to produce fibres of average diameter in the range of 100-150 nm and low polydispersity. The hydrophobic modification has not only increased the fibre diameter, but also the obtained layers were homogenous. At the nanoscale, the hybrid copolymer exhibited an unusual hairy topography. Moreover, the hardness and tensile properties of the hybrid were found to be superior compared to fibres made of unmodified HA. Particularly, this reinforcement was achieved at the longitudinal direction. Additionally, this work reports the use in the composition of a water-soluble copolymer containing photo cross-linkable moieties to produce insoluble materials post-electrospinning. The derivatives as well as their nanofibrous mats retain the biocompatibility of the natural polymers used for the fabrication.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc18033235
003      
CZ-PrNML
005      
20200526092703.0
007      
ta
008      
181008s2018 xxu f 000 0|eng||
009      
AR
024    7_
$a 10.1007/s10856-018-6045-5 $2 doi
035    __
$a (PubMed)29546462
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a xxu
100    1_
$a Huerta-Ángeles, Gloria $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic. huerta-angeles@contipro.com.
245    10
$a Aligned nanofibres made of poly(3-hydroxybutyrate) grafted to hyaluronan for potential healthcare applications / $c G. Huerta-Ángeles, K. Knotková, P. Knotek, O. Židek, M. Brandejsová, M. Pokorný, H. Vagnerová, I. Roy, V. Velebný,
520    9_
$a In this work, a hybrid copolymer consisting of poly(3-hydroxybutyrate) grafted to hyaluronic acid (HA) was synthesised and characterised. Once formed, the P(3HB)-g-HA copolymer was soluble in water allowing a green electrospinning process. The diameters of nanofibres can be tailored by simply varying the Mw of polymer. The optimization of the process allowed to produce fibres of average diameter in the range of 100-150 nm and low polydispersity. The hydrophobic modification has not only increased the fibre diameter, but also the obtained layers were homogenous. At the nanoscale, the hybrid copolymer exhibited an unusual hairy topography. Moreover, the hardness and tensile properties of the hybrid were found to be superior compared to fibres made of unmodified HA. Particularly, this reinforcement was achieved at the longitudinal direction. Additionally, this work reports the use in the composition of a water-soluble copolymer containing photo cross-linkable moieties to produce insoluble materials post-electrospinning. The derivatives as well as their nanofibrous mats retain the biocompatibility of the natural polymers used for the fabrication.
650    12
$a vstřebatelné implantáty $7 D020341
650    12
$a biokompatibilní materiály $x chemická syntéza $x chemie $7 D001672
650    _2
$a biomechanika $7 D001696
650    _2
$a poskytování zdravotní péče $7 D003695
650    _2
$a zdravotnické prostředky $7 D004864
650    _2
$a kyselina hyaluronová $x chemie $7 D006820
650    _2
$a hydrofobní a hydrofilní interakce $7 D057927
650    _2
$a hydroxybutyráty $x chemická syntéza $x chemie $7 D006885
650    _2
$a nanovlákna $x chemie $7 D057139
650    _2
$a polyestery $x chemická syntéza $x chemie $7 D011091
650    _2
$a polymery $x chemická syntéza $x chemie $7 D011108
650    _2
$a tkáňové podpůrné struktury $x chemie $7 D054457
655    _2
$a časopisecké články $7 D016428
700    1_
$a Knotková, Kateřina $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic.
700    1_
$a Knotek, Petr $u Department of General and Inorganic Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, Pardubice, 532 10, Czech Republic.
700    1_
$a Žídek, Ondřej $7 xx0248179 $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic.
700    1_
$a Brandejsová, Martina $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic.
700    1_
$a Pokorný, Marek $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic.
700    1_
$a Vagnerová, Hana $u Contipro a.s., Dolní Dobrouč 401, Dolní Dobrouč, 561 02, Czech Republic.
700    1_
$a Roy, Ipsita $u Department of Life Science, Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London, W1W 6UW, UK.
700    1_
$a Velebný, Vladimir $u Department of Life Science, Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London, W1W 6UW, UK.
773    0_
$w MED00002780 $t Journal of materials science. Materials in medicine $x 1573-4838 $g Roč. 29, č. 3 (2018), s. 32
856    41
$u https://pubmed.ncbi.nlm.nih.gov/29546462 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20181008 $b ABA008
991    __
$a 20200526092659 $b ABA008
999    __
$a ok $b bmc $g 1339398 $s 1030229
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2018 $b 29 $c 3 $d 32 $e 20180315 $i 1573-4838 $m Journal of materials science. Materials in medicine $n J Mater Sci Mater Med $x MED00002780
LZP    __
$a Pubmed-20181008

Najít záznam

Citační ukazatele

    Možnosti archivace