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Clinical and laboratory predictors of Infectious Complications in patients after Out-of-Hospital Cardiac Arrest
J. Kroupa, J. Knot, J. Ulman, F. Bednar, A. Dohnalova, Z. Motovska,
Jazyk angličtina Země Spojené státy americké
Typ dokumentu časopisecké články, pozorovací studie, práce podpořená grantem
NLK
ProQuest Central
od 2003-03-01 do Před 2 měsíci
Nursing & Allied Health Database (ProQuest)
od 2003-03-01 do Před 2 měsíci
Health & Medicine (ProQuest)
od 2003-03-01 do Před 2 měsíci
- MeSH
- antibakteriální látky terapeutické užití MeSH
- antibiotická profylaxe statistika a číselné údaje MeSH
- C-reaktivní protein metabolismus MeSH
- čas zasáhnout při rozvinutí nemoci MeSH
- délka pobytu statistika a číselné údaje MeSH
- infarkt myokardu s elevacemi ST úseků komplikace terapie MeSH
- infekce dýchací soustavy komplikace prevence a kontrola MeSH
- kalcitonin metabolismus MeSH
- koronární jednotky statistika a číselné údaje MeSH
- lidé středního věku MeSH
- lidé MeSH
- procedury zbytečné MeSH
- sepse komplikace prevence a kontrola MeSH
- terapeutická hypotermie metody MeSH
- umělé dýchání statistika a číselné údaje MeSH
- urgentní služby nemocnice statistika a číselné údaje MeSH
- zástava srdce mimo nemocnici komplikace terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
PURPOSE: Identification of clinical and laboratory predictors related to Infectious Complications (ICs) in patients after Out-of-Hospital Cardiac Arrest (OHCA). METHODS: Patients, aged >18, after an OHCA between 9/2013 and 11/2015, surviving >24h, were studied. RESULTS: Study group consisted of 42 patients (mean age 63.4years, 88.1% men). Forty percent of patients had IC; lower respiratory tract infections were most common (87.5% of cases). ICs were more common in patients receiving Targeted Temperature Management (50% vs. 10%; p=0.032). Antibiotics were used in 85.7% of patients. The mean time to therapy initiation was 9.6 (SD 7.1) hours after admission. The mean course of treatment was 9.0 (SD 6.2) days. Fifty-three percent of patients receiving early antibiotic treatment didn't have IC. Initial antibiotic therapy was changed more often in patients with IC (75% vs. 38.9%; p=0.045). C-Reactive Protein, Procalcitonin, Troponin and White Blood Cell count values were higher in patients with IC. CONCLUSION: Early initiated antibiotic treatment is overused in patients after OHCA. This practice is associated with necessitating antibiotic change in the majority of patients with IC. Assessment of clinical and laboratory parameters in the first days after OHCA increases the likelihood of appropriate ATB therapy.
Cardiocenter 3rd Faculty of Medicine Charles University Prague Czech Republic
Institute of Physiology 1st Faculty of Medicine Charles University Prague Czech Republic
Citace poskytuje Crossref.org
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- $a PURPOSE: Identification of clinical and laboratory predictors related to Infectious Complications (ICs) in patients after Out-of-Hospital Cardiac Arrest (OHCA). METHODS: Patients, aged >18, after an OHCA between 9/2013 and 11/2015, surviving >24h, were studied. RESULTS: Study group consisted of 42 patients (mean age 63.4years, 88.1% men). Forty percent of patients had IC; lower respiratory tract infections were most common (87.5% of cases). ICs were more common in patients receiving Targeted Temperature Management (50% vs. 10%; p=0.032). Antibiotics were used in 85.7% of patients. The mean time to therapy initiation was 9.6 (SD 7.1) hours after admission. The mean course of treatment was 9.0 (SD 6.2) days. Fifty-three percent of patients receiving early antibiotic treatment didn't have IC. Initial antibiotic therapy was changed more often in patients with IC (75% vs. 38.9%; p=0.045). C-Reactive Protein, Procalcitonin, Troponin and White Blood Cell count values were higher in patients with IC. CONCLUSION: Early initiated antibiotic treatment is overused in patients after OHCA. This practice is associated with necessitating antibiotic change in the majority of patients with IC. Assessment of clinical and laboratory parameters in the first days after OHCA increases the likelihood of appropriate ATB therapy.
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