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Adipocytokines and new onset diabetes mellitus after transplantation
Dominika Goldmannová, Jaromíra Spurná, Ondřej Krystyník, Jan Schovánek, Lubica Cibičková, David Karásek, Josef Zadražil
Journal of Applied Biomedicine.
2018 ;
16 (4) :
247-254.
Language English Country Czech Republic
Document type Research Support, Non-U.S. Gov't, Review
Persistent link
https://www.medvik.cz/link/bmc18039886
- MeSH
- Adipokines biosynthesis metabolism adverse effects MeSH
- Adiponectin biosynthesis metabolism adverse effects MeSH
- Diabetes Mellitus * epidemiology etiology physiopathology MeSH
- Fibroblast Growth Factors biosynthesis metabolism adverse effects MeSH
- Immunosuppressive Agents adverse effects therapeutic use MeSH
- Plasminogen Activator Inhibitor 1 genetics metabolism adverse effects MeSH
- Insulin-Like Growth Factor II biosynthesis genetics metabolism MeSH
- Insulin Resistance genetics immunology MeSH
- Humans MeSH
- Tumor Necrosis Factor-alpha biosynthesis metabolism adverse effects MeSH
- Kidney Transplantation MeSH
- Adipose Tissue immunology metabolism MeSH
- Check Tag
- Humans MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
Diabetes mellitus is a very common metabolic disease with a rising incidence. It is one of the most serious comorbidities in renal transplant recipients. New-onset diabetes after renal transplantation (NODAT) is associated with poor graft function, higher rates of cardiovascular complications and a poor prognosis. Adipocytokines, synthetized by adipose tissue influence metabolic pathways and disorders in various ways. In this review article, we chose the most researched adipocytokines and evaluated their relationship to posttransplant diabetes mellitus. The aim of this paper is to summarize current knowledge and discuss their perspective role in diagnostics or therapy of the new onset diabetes mellitus after transplantation.
References provided by Crossref.org
Bibliography, etc.
Literatura
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