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The optimal bowel preparation intervals before colonoscopy: A randomized study comparing polyethylene glycol and low-volume solutions

V. Kojecky, J. Matous, R. Keil, M. Dastych, Z. Zadorova, M. Varga, R. Kroupa, J. Dolina, M. Misurec, A. Hep, M. Griva,

. 2018 ; 50 (3) : 271-276. [pub] 20171101

Jazyk angličtina Země Nizozemsko

Typ dokumentu srovnávací studie, časopisecké články, multicentrická studie, randomizované kontrolované studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc19001115

BACKGROUND & AIMS: The optimal duration of bowel preparation has only been assessed for polyethylene glycol (PEG). The aim of the study was to determine the intervals for achieving a satisfactory quality/tolerability of the preparation using PEG/ascorbic acid (PEGA) and sodium picosulphate/magnesium citrate (SPMC), and to compare them with 4L of PEG. METHODS: A randomized, endoscopist-blinded, multicentre study. The 612 outpatients referred to a colonoscopy, were prepared using PEG, SPMC, PEGA. The quality, tolerability, duration of the preparation, and the interval from the end of the preparation to the colonoscopy was assessed. RESULTS: Optimum duration of the preparation was similar for both PEG and SPMC (≥7.3 vs. ≥8.8 h, overall ≥8.4 h). Optimum interval to the colonoscopy was ≤11.8 h and did not differ between preparations (PEG, PEGA ≤ 11.8, SPMC ≤ 13.3 h). These times were the only predictors for a satisfactory preparation. The tolerability depends on the product type (SPMC) only. Timing of the preparation or the other factors had no impact on tolerability. CONCLUSION: The optimum intervals for bowel preparation are identical for all preparations. Satisfactory preparation is achived at the preparation length ≥8.4 h and the time to colonoscopy ≤11.8 h.

Citace poskytuje Crossref.org

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$a Matous, Jan $u 2nd Dept. of Internal Medicine, Third Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
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$a Keil, Radan $u Dept. of Internal Medicine, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.
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$a Dastych, Milan $u Dept. of Gastroenterology and Internal Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
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$a Varga, Michal $u Internal Clinic, Bata Regional Hospital, Zlin, Czech Republic.
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$a Kroupa, Radek $u Dept. of Gastroenterology and Internal Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic.
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$a Dolina, Jiri $u Dept. of Gastroenterology and Internal Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czech Republic. Electronic address: jidoli@post.cz.
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$a Misurec, Miroslav $u Internal Clinic, Bata Regional Hospital, Zlin, Czech Republic.
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