-
Je něco špatně v tomto záznamu ?
Ultrasound characteristics of endometrial cancer as defined by International Endometrial Tumor Analysis (IETA) consensus nomenclature: prospective multicenter study
E. Epstein, D. Fischerova, L. Valentin, AC. Testa, D. Franchi, P. Sladkevicius, F. Frühauf, PG. Lindqvist, F. Mascilini, R. Fruscio, LA. Haak, G. Opolskiene, MA. Pascual, JL. Alcazar, V. Chiappa, S. Guerriero, JW. Carlson, C. Van Holsbeke, FPG....
Jazyk angličtina Země Anglie, Velká Británie
Typ dokumentu hodnotící studie, časopisecké články, multicentrická studie
PubMed
28944985
DOI
10.1002/uog.18909
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- konsensuální konference jako téma MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory endometria klasifikace diagnostické zobrazování patologie MeSH
- prospektivní studie MeSH
- průřezové studie MeSH
- reprodukovatelnost výsledků MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- stupeň nádoru * MeSH
- terminologie jako téma MeSH
- ultrasonografie dopplerovská barevná normy MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- hodnotící studie MeSH
- multicentrická studie MeSH
OBJECTIVE: To describe the sonographic features of endometrial cancer in relation to tumor stage, grade and histological type, using the International Endometrial Tumor Analysis (IETA) terminology. METHODS: This was a prospective multicenter study of 1714 women with biopsy-confirmed endometrial cancer undergoing standardized transvaginal grayscale and Doppler ultrasound examination according to the IETA study protocol, by experienced ultrasound examiners using high-end ultrasound equipment. Clinical and sonographic data were entered into a web-based database. We assessed how strongly sonographic characteristics, according to IETA, were associated with outcome at hysterectomy, i.e. tumor stage, grade and histological type, using univariable logistic regression and the c-statistic. RESULTS: In total, 1538 women were included in the final analysis. Median age was 65 (range, 27-98) years, median body mass index was 28.4 (range 16-67) kg/m2 , 1377 (89.5%) women were postmenopausal and 1296 (84.3%) reported abnormal vaginal bleeding. Grayscale and color Doppler features varied according to grade and stage of tumor. High-risk tumors, compared with low-risk tumors, were less likely to have regular endometrial-myometrial junction (difference of -23%; 95% CI, -27 to -18%), were larger (mean endometrial thickness; difference of +9%; 95% CI, +8 to +11%), and were more likely to have non-uniform echogenicity (difference of +7%; 95% CI, +1 to +13%), a multiple, multifocal vessel pattern (difference of +21%; 95% CI, +16 to +26%) and a moderate or high color score (difference of +22%; 95% CI, +18 to +27%). CONCLUSION: Grayscale and color Doppler sonographic features are associated with grade and stage of tumor, and differ between high- and low-risk endometrial cancer. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Center of Obstetrics and Gynecology Vilnius University Hospital Santariskiu Clinic Vilnius Lithuania
Clinic of Obstetrics and Gynecology University of Milan Bicocca San Gerardo Hospital Monza Italy
Department of Development and Regeneration KU Leuven Leuven Belgium
Department of Gynecological Oncology Catholic University of the Sacred Heart Rome Italy
Department of Gynecological Oncology European Institute of Oncology Milan Italy
Department of Obstetrics and Gynecology Clinica Universidad de Navarra Pamplona Spain
Department of Obstetrics and Gynecology Clinical Sciences Institute L Sacco Milan Italy
Department of Obstetrics and Gynecology Karolinska University Hospital Huddinge Stockholm Sweden
Department of Obstetrics and Gynecology National Cancer Institute Milan Italy
Department of Obstetrics and Gynecology Skåne University Hospital Malmö Lund University Sweden
Department of Obstetrics and Gynecology University Hospital Leuven Leuven Belgium
Department of Obstetrics and Gynecology Ziekenhuis Oost Limburg Genk Belgium
Department of Obstetrics Gynecology and Reproduction Hospital Universitario Dexeus Barcelona Spain
Department of Pathology Karolinska University Hospital Stockholm Sweden
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19001174
- 003
- CZ-PrNML
- 005
- 20190115110756.0
- 007
- ta
- 008
- 190107s2018 enk f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1002/uog.18909 $2 doi
- 035 __
- $a (PubMed)28944985
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a enk
- 100 1_
- $a Epstein, E $u Department of Clinical Science and Education, Karolinska Institutet, and Department of Obstetrics and Gynecology, Södersjukhuset, Stockholm, Sweden.
- 245 10
- $a Ultrasound characteristics of endometrial cancer as defined by International Endometrial Tumor Analysis (IETA) consensus nomenclature: prospective multicenter study / $c E. Epstein, D. Fischerova, L. Valentin, AC. Testa, D. Franchi, P. Sladkevicius, F. Frühauf, PG. Lindqvist, F. Mascilini, R. Fruscio, LA. Haak, G. Opolskiene, MA. Pascual, JL. Alcazar, V. Chiappa, S. Guerriero, JW. Carlson, C. Van Holsbeke, FPG. Leone, B. De Moor, T. Bourne, B. van Calster, A. Installe, D. Timmerman, JY. Verbakel, T. Van den Bosch,
- 520 9_
- $a OBJECTIVE: To describe the sonographic features of endometrial cancer in relation to tumor stage, grade and histological type, using the International Endometrial Tumor Analysis (IETA) terminology. METHODS: This was a prospective multicenter study of 1714 women with biopsy-confirmed endometrial cancer undergoing standardized transvaginal grayscale and Doppler ultrasound examination according to the IETA study protocol, by experienced ultrasound examiners using high-end ultrasound equipment. Clinical and sonographic data were entered into a web-based database. We assessed how strongly sonographic characteristics, according to IETA, were associated with outcome at hysterectomy, i.e. tumor stage, grade and histological type, using univariable logistic regression and the c-statistic. RESULTS: In total, 1538 women were included in the final analysis. Median age was 65 (range, 27-98) years, median body mass index was 28.4 (range 16-67) kg/m2 , 1377 (89.5%) women were postmenopausal and 1296 (84.3%) reported abnormal vaginal bleeding. Grayscale and color Doppler features varied according to grade and stage of tumor. High-risk tumors, compared with low-risk tumors, were less likely to have regular endometrial-myometrial junction (difference of -23%; 95% CI, -27 to -18%), were larger (mean endometrial thickness; difference of +9%; 95% CI, +8 to +11%), and were more likely to have non-uniform echogenicity (difference of +7%; 95% CI, +1 to +13%), a multiple, multifocal vessel pattern (difference of +21%; 95% CI, +16 to +26%) and a moderate or high color score (difference of +22%; 95% CI, +18 to +27%). CONCLUSION: Grayscale and color Doppler sonographic features are associated with grade and stage of tumor, and differ between high- and low-risk endometrial cancer. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a senioři $7 D000368
- 650 _2
- $a senioři nad 80 let $7 D000369
- 650 _2
- $a konsensuální konference jako téma $7 D003245
- 650 _2
- $a průřezové studie $7 D003430
- 650 _2
- $a nádory endometria $x klasifikace $x diagnostické zobrazování $x patologie $7 D016889
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a lidé středního věku $7 D008875
- 650 12
- $a stupeň nádoru $7 D060787
- 650 _2
- $a prospektivní studie $7 D011446
- 650 _2
- $a reprodukovatelnost výsledků $7 D015203
- 650 _2
- $a terminologie jako téma $7 D009626
- 650 _2
- $a ultrasonografie dopplerovská barevná $x normy $7 D018615
- 655 _2
- $a hodnotící studie $7 D023362
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a multicentrická studie $7 D016448
- 700 1_
- $a Fischerova, D $u Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
- 700 1_
- $a Valentin, L $u Department of Obstetrics and Gynecology, Skåne University Hospital, Malmö, Lund University, Sweden.
- 700 1_
- $a Testa, A C $u Department of Gynecological Oncology, Catholic University of the Sacred Heart, Rome, Italy.
- 700 1_
- $a Franchi, D $u Department of Gynecological Oncology, European Institute of Oncology, Milan, Italy.
- 700 1_
- $a Sladkevicius, P $u Department of Obstetrics and Gynecology, Skåne University Hospital, Malmö, Lund University, Sweden.
- 700 1_
- $a Frühauf, F $u Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
- 700 1_
- $a Lindqvist, P G $u Department of Obstetrics and Gynecology, Karolinska University Hospital Huddinge, Stockholm, Sweden.
- 700 1_
- $a Mascilini, F $u Department of Gynecological Oncology, Catholic University of the Sacred Heart, Rome, Italy.
- 700 1_
- $a Fruscio, R $u Clinic of Obstetrics and Gynecology, University of Milan Bicocca, San Gerardo Hospital, Monza, Italy.
- 700 1_
- $a Haak, L A $u Institute for the Care of Mother and Child, Prague and Third Faculty of Medicine, Charles University, Prague, Czech Republic.
- 700 1_
- $a Opolskiene, G $u Center of Obstetrics and Gynecology, Vilnius University Hospital, Santariskiu Clinic, Vilnius, Lithuania.
- 700 1_
- $a Pascual, M A $u Department of Obstetrics, Gynecology, and Reproduction, Hospital Universitario Dexeus, Barcelona, Spain.
- 700 1_
- $a Alcazar, J L $u Department of Obstetrics and Gynecology, Clinica Universidad de Navarra, Pamplona, Spain.
- 700 1_
- $a Chiappa, V $u Department of Obstetrics and Gynecology, National Cancer Institute, Milan, Italy.
- 700 1_
- $a Guerriero, S $u Department of Obstetrics and Gynecology, University of Cagliari, Policlinico Universitario Duilio Casula, Monserrato, Cagliari, Italy.
- 700 1_
- $a Carlson, J W $u Department of Pathology, Karolinska University Hospital, Stockholm, Sweden.
- 700 1_
- $a Van Holsbeke, C $u Department of Obstetrics and Gynecology, Ziekenhuis Oost-Limburg, Genk, Belgium.
- 700 1_
- $a Leone, F P G $u Department of Obstetrics and Gynecology, Clinical Sciences Institute, L. Sacco, Milan, Italy.
- 700 1_
- $a De Moor, B $u Department of Electrical Engineering, ESAT-SCD, STADIUS Center for Dynamical Systems, Signal Processing and Data Analysis, KU Leuven, and imec, Leuven, Belgium.
- 700 1_
- $a Bourne, T $u Department of Obstetrics and Gynaecology, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, UK. Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
- 700 1_
- $a van Calster, B $u Department of Development and Regeneration, KU Leuven, Leuven, Belgium.
- 700 1_
- $a Installe, A $u Department of Electrical Engineering, ESAT-SCD, STADIUS Center for Dynamical Systems, Signal Processing and Data Analysis, KU Leuven, and imec, Leuven, Belgium.
- 700 1_
- $a Timmerman, D $u Department of Development and Regeneration, KU Leuven, Leuven, Belgium. Department of Obstetrics and Gynecology, University Hospital Leuven, Leuven, Belgium.
- 700 1_
- $a Verbakel, J Y $u Department of Development and Regeneration, KU Leuven, Leuven, Belgium. Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
- 700 1_
- $a Van den Bosch, T $u Department of Obstetrics and Gynecology, University Hospital Leuven, Leuven, Belgium.
- 773 0_
- $w MED00010717 $t Ultrasound in obstetrics & gynecology the official journal of the International Society of Ultrasound in Obstetrics and Gynecology $x 1469-0705 $g Roč. 51, č. 6 (2018), s. 818-828
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/28944985 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y a $z 0
- 990 __
- $a 20190107 $b ABA008
- 991 __
- $a 20190115111006 $b ABA008
- 999 __
- $a ok $b bmc $g 1365081 $s 1039297
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2018 $b 51 $c 6 $d 818-828 $i 1469-0705 $m Ultrasound in obstetrics & gynecology $n Ultrasound Obstet Gynecol $x MED00010717
- LZP __
- $a Pubmed-20190107
