-
Je něco špatně v tomto záznamu ?
Celiac disease and neurological manifestations of gluten sensitivity. What do tey share in common?
Rubén Peña, Gabriela Román, Natalia Zuloaga, Magdalena Araya
Jazyk angličtina Země Spojené státy americké
- MeSH
- ataxie etiologie komplikace MeSH
- celiakie * komplikace patofyziologie MeSH
- epilepsie etiologie komplikace MeSH
- gluteny škodlivé účinky MeSH
- lidé MeSH
- migréna etiologie komplikace MeSH
- nemoci centrálního nervového systému * etiologie komplikace MeSH
- nemoci periferního nervového systému etiologie komplikace MeSH
- Purkyňovy buňky patologie MeSH
- receptory N-methyl-D-aspartátu MeSH
- transglutaminasy škodlivé účinky MeSH
- Check Tag
- lidé MeSH
Knowledge on the clinical, autoimmune, genetic and more recently microbiome and epigenetic interactions in celiac disease (CD) is consistently improving; however, the pathogenic mechanisms of neurological manifestations of gluten sensitivity (NMGS) and their potential relationship with CD remain unclear. Difficulties in assessing both conditions include their highly variable clinical manifestations and the insufficient sensitivity and specificities of currently available diagnostics tools. Patients with neurological manifestations that respond to gluten withdrawal may or may not present enteropathy and others having demonstrable mucosal damage may or may not respond to GFD. Current pathogenic hypotheses that may relate both conditions, the spectrum of clinical manifestations, diagnostic problems, including differences in types and subtypes of antibodies described for diagnosis and the effects of gluten-free diet are reviewed. The evidence show that decisions based on clinical data may be successful for patient management, but do not allow drawing conclusions on the relations between CD and NMGS.
Literatura
- 000
- 00000naa a2200000 a 4500
- 001
- bmc19017506
- 003
- CZ-PrNML
- 005
- 20211221164602.0
- 007
- ta
- 008
- 190516s2018 xxua f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.12691/ijcd-6-3-5 $2 doi
- 040 __
- $a ABA008 $d ABA008 $e AACR2 $b cze
- 041 0_
- $a eng
- 044 __
- $a xxu
- 100 1_
- $a Peña, Rubén $u Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile; Fellow, Pediatric Gastroenterology and Nutrition Program, Faculty of Medicine, University of Chile, Santiago, Chile
- 245 10
- $a Celiac disease and neurological manifestations of gluten sensitivity. What do tey share in common? / $c Rubén Peña, Gabriela Román, Natalia Zuloaga, Magdalena Araya
- 504 __
- $a Literatura
- 520 9_
- $a Knowledge on the clinical, autoimmune, genetic and more recently microbiome and epigenetic interactions in celiac disease (CD) is consistently improving; however, the pathogenic mechanisms of neurological manifestations of gluten sensitivity (NMGS) and their potential relationship with CD remain unclear. Difficulties in assessing both conditions include their highly variable clinical manifestations and the insufficient sensitivity and specificities of currently available diagnostics tools. Patients with neurological manifestations that respond to gluten withdrawal may or may not present enteropathy and others having demonstrable mucosal damage may or may not respond to GFD. Current pathogenic hypotheses that may relate both conditions, the spectrum of clinical manifestations, diagnostic problems, including differences in types and subtypes of antibodies described for diagnosis and the effects of gluten-free diet are reviewed. The evidence show that decisions based on clinical data may be successful for patient management, but do not allow drawing conclusions on the relations between CD and NMGS.
- 650 12
- $a celiakie $x komplikace $x patofyziologie $7 D002446
- 650 _2
- $a gluteny $x škodlivé účinky $7 D005983
- 650 _2
- $a Purkyňovy buňky $x patologie $7 D011689
- 650 _2
- $a transglutaminasy $x škodlivé účinky $7 D011503
- 650 _2
- $a receptory N-methyl-D-aspartátu $7 D016194
- 650 _2
- $a ataxie $x etiologie $x komplikace $7 D001259
- 650 _2
- $a nemoci periferního nervového systému $x etiologie $x komplikace $7 D010523
- 650 _2
- $a epilepsie $x etiologie $x komplikace $7 D004827
- 650 _2
- $a migréna $x etiologie $x komplikace $7 D008881
- 650 _2
- $a lidé $7 D006801
- 650 12
- $a nemoci centrálního nervového systému $x etiologie $x komplikace $7 D002493
- 700 1_
- $a Román, Gabriela $u Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile; Fellow, Pediatric Gastroenterology and Nutrition Program, Faculty of Medicine, University of Chile, Santiago, Chile
- 700 1_
- $a Zuloaga, Natalia $u Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile; Fellow, Pediatric Gastroenterology and Nutrition Program, Faculty of Medicine, University of Chile, Santiago, Chile
- 700 1_
- $a Araya, Magdalena $u Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile
- 773 0_
- $t International journal of celiac disease $x 2334-3427 $g Roč. 6, č. 3 (2018), s. 76-82 $w MED00186448
- 856 41
- $u http://www.sciepub.com/journal/index.aspx?id=ijcd $y domovská stránka časopisu
- 910 __
- $a ABA008 $b B 2748 $c 280 $y 0 $z 0
- 990 __
- $a 20190516101825 $b ABA008
- 991 __
- $a 20211221164557 $b ABA008
- 999 __
- $a kom $b bmc $g 1405287 $s 1056598
- BAS __
- $a 3
- BMC __
- $a 2018 $b 6 $c 3 $d 76-82 $i 2334-3427 $m International journal of celiac disease $x MED00186448
- LZP __
- $c NLK193 $d 20211221 $a NLK 2019-16/dk