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Mucinous Cystic Neoplasm of the Liver or Intraductal Papillary Mucinous Neoplasm of the Bile Duct? A Case Report and a Review of Literature
L. Kunovsky, Z. Kala, R. Svaton, P. Moravcik, J. Mazanec, J. Husty, V. Prochazka,
Language English Country Mexico
Document type Case Reports, Journal Article, Review
NLK
Medline Complete (EBSCOhost)
from 2013-11-01
ROAD: Directory of Open Access Scholarly Resources
from 2002
- MeSH
- Biopsy MeSH
- Cholangiography MeSH
- Diagnosis, Differential MeSH
- Dilatation, Pathologic MeSH
- Adult MeSH
- Hepatic Duct, Common pathology MeSH
- Hepatectomy MeSH
- Carcinoma in Situ complications diagnosis pathology surgery MeSH
- Humans MeSH
- Magnetic Resonance Imaging MeSH
- Neoplasms, Cystic, Mucinous, and Serous complications diagnosis pathology surgery MeSH
- Liver Neoplasms complications diagnosis pathology surgery MeSH
- Bile Duct Neoplasms diagnosis pathology MeSH
- Tomography, X-Ray Computed MeSH
- Predictive Value of Tests MeSH
- Disease Progression MeSH
- Tumor Burden MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
- Review MeSH
Mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are diagnoses that were classified by the World Health Organization in 2010 as mucin-producing bile duct tumors of the hepatobiliary system. The preoperative differential diagnosis between these two entities is difficult; the presence of a communication with the bile duct is usually considered as a typical sign of IPMN-B. However, the presence of an ovarian-like stroma (OLS) has been established to define the diagnosis of MCN-L. We present the case of a 33-year-old woman with a rapid progression of a cystic tumor of the liver. In 2 years, the lesion increased from 27 to 64 mm and a dilation of the left hepatic duct appeared. Percutaneous transhepatic drainage with a biopsy was performed. No malignant cells were found on biopsy. Because of the rapid progression of the cystic tumor and unclear malignant potential, left hemihepatectomy was performed. Even though tumor masses were present in the biliary duct, on the basis of the presence of OLS, histology finally confirmed MCN-L with intermediate-grade intraepithelial dysplasia to high-grade intraepithelial dysplasia. The patient is currently under oncologic follow-up with no signs of recurrence of the disease. We present a rare case where MCN-L caused a dilation of the left hepatic duct, a sign that is usually a characteristic of IPMN-B.
References provided by Crossref.org
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