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Fast and accurate compensation of signal offset for T2 mapping
J. Michálek, P. Hanzlíková, T. Trinh, D. Pacík,
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články
Grantová podpora
LM2015062
Ministerstvo Školství, Mládeže a Tělovýchovy
- MeSH
- algoritmy MeSH
- časové faktory MeSH
- fantomy radiodiagnostické MeSH
- interpretace obrazu počítačem metody MeSH
- lidé MeSH
- magnetická rezonanční tomografie * MeSH
- metoda nejmenších čtverců MeSH
- nádory prostaty diagnostické zobrazování MeSH
- počítačové zpracování obrazu metody MeSH
- poměr signál - šum MeSH
- pravděpodobnost MeSH
- regresní analýza MeSH
- reprodukovatelnost výsledků MeSH
- software MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: T2 maps are more vendor independent than other MRI protocols. Multi-echo spin-echo signal decays to a non-zero offset due to imperfect refocusing pulses and Rician noise, causing T2 overestimation by the vendor's 2-parameter algorithm. The accuracy of the T2 estimate is improved, if the non-zero offset is estimated as a third parameter. Three-parameter Levenberg-Marquardt (LM) T2 estimation takes several minutes to calculate, and it is sensitive to initial values. We aimed for a 3-parameter fitting algorithm that was comparably accurate, yet substantially faster. METHODS: Our approach gains speed by converting the 3-parameter minimisation problem into an empirically unimodal univariate problem, which is quickly minimised using the golden section line search (GS). RESULTS: To enable comparison, we propose a novel noise-masking algorithm. For clinical data, the agreement between the GS and the LM fit is excellent, yet the GS algorithm is two orders of magnitude faster. For synthetic data, the accuracy of the GS algorithm is on par with that of the LM fit, and the GS algorithm is significantly faster. The GS algorithm requires no parametrisation or initialisation by the user. DISCUSSION: The new GS T2 mapping algorithm offers a fast and much more accurate off-the-shelf replacement for the inaccurate 2-parameter fit in the vendor's software.
Department of Urology Medical School Masaryk University Jihlavská 20 62500 Brno Czech Republic
Department of Urology University Hospital Brno Jihlavská 20 62500 Brno Czech Republic
Citace poskytuje Crossref.org
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