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Reactive modifications of DNA nucleobases for labelling, bioconjugations, and cross-linking
I. Ivancová, DL. Leone, M. Hocek,
Current opinion in chemical biology.
2019 ;
52 (-) :
136-144.
[pub] 20190812
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
Perzistentní odkaz
https://www.medvik.cz/link/bmc20023612
- MeSH
- alkylace MeSH
- cykloadiční reakce MeSH
- DNA chemie MeSH
- reagencia zkříženě vázaná chemie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Modification of DNA with reactive groups and their post-synthetic transformations are useful for labelling, imaging, bioconjugations and cross-linking with other (bio)molecules. This review summarizes the recent progress in this field and covers transformations of oxo groups, cycloadditions, conjugate additions, alkylations, cross-couplings and other reactions. Examples of applications are given and the practicability and scope of the reactions are discussed.
Citace poskytuje Crossref.org
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