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Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic

M. Banach, PE. Penson, Z. Fras, M. Vrablik, D. Pella, Ž. Reiner, SM. Nabavi, A. Sahebkar, M. Kayikcioglu, M. Daccord, FH Europe and the International Lipid Expert Panel (ILEP),

. 2020 ; 158 (-) : 104891. [pub] 20200507

Language English Country Netherlands

Document type Journal Article

Persistent link   https://www.medvik.cz/link/bmc20024857

Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and the European FH Patient Network (FH Europe), we present brief recommendations on the management of adult patients with FH during the COVID-19 pandemic. We discuss the implications of COVID-19 infections for FH patients, the importance of continuing lipid-lowering therapy where possible, issues relating to safety monitoring and service delivery. We summarise the evidence for additional benefits of statins and other lipid-lowering drugs during viral infections. The recommendations do not override in any way the individual responsibility of physicians to make appropriate and accurate decisions taking into account the condition of a given patient and the doses, rules, and regulations applicable to drugs and devices at the time of their prescription/use.

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$a Banach, Maciej $u Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland; Polish Mother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Zielona Gora, Poland. Electronic address: maciej.banach@icloud.com.
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$a Brief recommendations on the management of adult patients with familial hypercholesterolemia during the COVID-19 pandemic / $c M. Banach, PE. Penson, Z. Fras, M. Vrablik, D. Pella, Ž. Reiner, SM. Nabavi, A. Sahebkar, M. Kayikcioglu, M. Daccord, FH Europe and the International Lipid Expert Panel (ILEP),
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$a Individuals with Familial Hypercholesterolaemia (FH) are at very high risk of cardiovascular disease, which is associated with poor outcomes from coronavirus infections. COVID-19 puts strain on healthcare systems and may impair access to routine FH services. On behalf of the International Lipid Expert Panel (ILEP) and the European FH Patient Network (FH Europe), we present brief recommendations on the management of adult patients with FH during the COVID-19 pandemic. We discuss the implications of COVID-19 infections for FH patients, the importance of continuing lipid-lowering therapy where possible, issues relating to safety monitoring and service delivery. We summarise the evidence for additional benefits of statins and other lipid-lowering drugs during viral infections. The recommendations do not override in any way the individual responsibility of physicians to make appropriate and accurate decisions taking into account the condition of a given patient and the doses, rules, and regulations applicable to drugs and devices at the time of their prescription/use.
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$a Penson, Peter E $u School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.
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$a Fras, Zlatko $u Division of Medicine, Centre for Preventive Cardiology, University Medical Centre Ljubljana, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
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$a Vrablik, Michal $u Third Department of Internal Medicine, First Faculty of Medicine, Charles University and General Faculty Hospital in Prague, Prague, Czech Republic.
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$a Pella, Daniel $u Department of Cardiology of the East Slovak Institute of Cardiovascular Disease and Faculty of Medicine PJ Safarik University, Kosice, Slovak Republic.
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$a Reiner, Željko $u Department of Internal Diseases University Hospital Center Zagreb School of Medicine, Zagreb University, Zagreb, Croatia.
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$a Nabavi, Seyed Mohammad $u Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran.
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$a Sahebkar, Amirhossein $u Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
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$a Kayikcioglu, Meral $u Department of Cardiology, Ege Üniversitesi School of Medicine, Izmir, Turkey.
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$a Daccord, Magdalena $u FH Europe, Europe. Electronic address: md@fheurope.org.
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