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Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain
N. Rieckmann, K. Neumann, S. Feger, P. Ibes, A. Napp, D. Preuß, H. Dreger, G. Feuchtner, F. Plank, V. Suchánek, J. Veselka, T. Engstrøm, KF. Kofoed, S. Schröder, T. Zelesny, M. Gutberlet, M. Woinke, P. Maurovich-Horvat, B. Merkely, P. Donnelly,...
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, multicentrická studie, pragmatická klinická studie
Grantová podpora
EC-GA 603266
Seventh Framework Programme - International
NLK
BioMedCentral
od 2003-12-01
BioMedCentral Open Access
od 2003
Directory of Open Access Journals
od 2003
Free Medical Journals
od 2003
PubMed Central
od 2003
Europe PubMed Central
od 2003
ProQuest Central
od 2009-01-01
Open Access Digital Library
od 2003-01-01
Open Access Digital Library
od 2003-01-01
Open Access Digital Library
od 2003-01-01
Medline Complete (EBSCOhost)
od 2003-01-06
Health & Medicine (ProQuest)
od 2009-01-01
Public Health Database (ProQuest)
od 2009-01-01
ROAD: Directory of Open Access Scholarly Resources
od 2003
Springer Nature OA/Free Journals
od 2003-12-01
- MeSH
- angina pectoris klasifikace diagnóza patofyziologie MeSH
- kvalita života * MeSH
- lidé středního věku MeSH
- lidé MeSH
- nemoci koronárních tepen diagnóza patofyziologie MeSH
- pilotní projekty MeSH
- průzkumy a dotazníky MeSH
- rozložení podle pohlaví MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- pragmatická klinická studie MeSH
BACKGROUND: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD. METHODS: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale. RESULTS: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p < 0.01), and highest anxiety levels (8.3 ± 4.1, 7.5 ± 4.1, 6.5 ± 4.0, 4.7 ± 4.5, respectively, all adjusted p < 0.01). On all other measures, patients with typical or atypical angina had lower HRQoL compared to the two other groups (all adjusted p < 0.05). HRQoL did not differ between patients with and without obstructive CAD while women had worse HRQoL compared with men, irrespective of age and angina type. CONCLUSIONS: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women. TRIAL REGISTRATION: Clinicaltrials.gov, NCT02400229.
BHF Centre of Research Excellence Glasgow University Glasgow UK
Department of Cardiology ALB FILS KLINIKEN GmbH Goeppingen Germany
Department of Cardiology Azienda Ospedaliera Brotzu Cagliari CA Italy
Department of Cardiology Basurto Hospital Bilbao Spain
Department of Cardiology Centro Hospitalar de Vila Nova de Gaia Espinho Vila Nova de Gaia Portugal
Department of Cardiology Motol University Hospital Prague Czech Republic
Department of Cardiology Paul Stradins Clinical University Hospital Riga Latvia
Department of Cardiology Rigshospitalet University of Copenhagen Copenhagen Denmark
Department of Cardiology Royal Liverpool University Hospital Liverpool UK
Department of Cardiology Southeastern Health and Social Care Trust Belfast UK
Department of Cardiology St Vincent's University Hospital Dublin Ireland
Department of Cardiology University of Leipzig Heart Centre Leipzig Germany
Department of Cardiology Wojewodzki Szpital Specjalistyczny We Wroclawiu Wroclaw Poland
Department of Imaging Methods Motol University Hospital Prague Czech Republic
Department of Internal Medicine 3 Cardiology Innsbruck Medical University Innsbruck Austria
Department of Radiology Aintree University Hospital Liverpool UK
Department of Radiology ALB FILS KLINIKEN GmbH Goeppingen Germany
Department of Radiology Basurto Hospital Bilbao Spain
Department of Radiology Innsbruck Medical University Innsbruck Austria
Department of Radiology Southeastern Health and Social Care Trust Belfast UK
Department of Radiology St Vincent's University Hospital Dublin Ireland
Department of Radiology University of Cagliari Cagliari CA Italy
Department of Radiology University of Leipzig Heart Centre Leipzig Germany
Department of Radiology Wojewodzki Szpital Specjalistyczny We Wroclawiu Wroclaw Poland
Heart and Vascular Center Semmelweis University Budapest Hungary
Heart Center Turku University Hospital and University of Turku Turku Finland
Osteba Basque Office for Health Technology Assessment Ministry for Health Basque Country Spain
Population Health Sciences Bristol Medical School University of Bristol Bristol UK
The National Institute of Cardiology Warsaw Poland
Turku PET Centre Turku University Hospital and University of Turku Turku Finland
Citace poskytuje Crossref.org
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- $a Rieckmann, Nina $u Institute of Public Health, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. nina.rieckmann@charite.de.
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- $a Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain / $c N. Rieckmann, K. Neumann, S. Feger, P. Ibes, A. Napp, D. Preuß, H. Dreger, G. Feuchtner, F. Plank, V. Suchánek, J. Veselka, T. Engstrøm, KF. Kofoed, S. Schröder, T. Zelesny, M. Gutberlet, M. Woinke, P. Maurovich-Horvat, B. Merkely, P. Donnelly, P. Ball, JD. Dodd, M. Hensey, B. Loi, L. Saba, M. Francone, M. Mancone, M. Berzina, A. Erglis, A. Vaitiekiene, L. Zajanckauskiene, T. Harań, MI. Suckiel, R. Faria, V. Gama-Ribeiro, I. Benedek, I. Rodean, F. Adjić, N. Čemerlić Adjić, J. Rodriguez-Palomares, B. Garcia Del Blanco, K. Brooksbank, D. Collison, G. Davis, E. Thwaite, J. Knuuti, A. Saraste, C. Kępka, M. Kruk, T. Benedek, M. Ratiu, AN. Neskovic, R. Vidakovic, I. Diez, I. Lecumberri, M. Fisher, B. Ruzsics, W. Hollingworth, I. Gutiérrez-Ibarluzea, M. Dewey, J. Müller-Nordhorn,
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- $a BACKGROUND: Health-related quality of life (HRQoL) is impaired in patients with stable angina but patients often present with other forms of chest pain. The aim of this study was to compare the pre-diagnostic HRQoL in patients with suspected coronary artery disease (CAD) according to angina type, gender, and presence of obstructive CAD. METHODS: From the pilot study for the European DISCHARGE trial, we analysed data from 24 sites including 1263 patients (45.9% women, 61.1 ± 11.3 years) who were clinically referred for invasive coronary angiography (ICA; 617 patients) or coronary computed tomography angiography (CTA; 646 patients). Prior to the procedures, patients completed HRQoL questionnaires: the Short Form (SF)-12v2, the EuroQoL (EQ-5D-3 L) and the Hospital Anxiety and Depression Scale. RESULTS: Fifty-five percent of ICA and 35% of CTA patients had typical angina, 23 and 33% had atypical angina, 18 and 28% had non-anginal chest discomfort and 5 and 5% had other chest discomfort, respectively. Patients with typical angina had the poorest physical functioning compared to the other angina groups (SF-12 physical component score; 41.2 ± 8.8, 43.3 ± 9.1, 46.2 ± 9.0, 46.4 ± 11.4, respectively, all age and gender-adjusted p < 0.01), and highest anxiety levels (8.3 ± 4.1, 7.5 ± 4.1, 6.5 ± 4.0, 4.7 ± 4.5, respectively, all adjusted p < 0.01). On all other measures, patients with typical or atypical angina had lower HRQoL compared to the two other groups (all adjusted p < 0.05). HRQoL did not differ between patients with and without obstructive CAD while women had worse HRQoL compared with men, irrespective of age and angina type. CONCLUSIONS: Prior to a diagnostic procedure for stable chest pain, HRQoL is associated with chest pain characteristics, but not with obstructive CAD, and is significantly lower in women. TRIAL REGISTRATION: Clinicaltrials.gov, NCT02400229.
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- $a Neumann, Konrad $u Institute of Public Health, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Institute of Biometry and Clinical Epidemiology and Berlin Institute of Health, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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- 700 1_
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