• Je něco špatně v tomto záznamu ?

Understanding attitudes and behaviors towards cell-free DNA-based noninvasive prenatal testing (NIPT): A survey of European health-care providers

A. Benachi, J. Caffrey, P. Calda, E. Carreras, JC. Jani, MD. Kilby, HG. Klein, G. Rizzo, Y. Yaron,

. 2020 ; 63 (1) : 103616. [pub] 20190114

Jazyk angličtina Země Nizozemsko

Typ dokumentu časopisecké články

Perzistentní odkaz   https://www.medvik.cz/link/bmc20028636

Cell-free DNA-based noninvasive prenatal testing (cfDNA) is a relatively new screening tool that analyzes cfDNA circulating in maternal plasma to screen for aneuploidies. Since its introduction, cfDNA has been rapidly adopted by health care providers (HCPs). This rapid adoption, as well as progressive developments in the technology, requires professional societies to continuously update their guidelines to indicate the broadening scope both in terms of test indications and patient populations for whom it has become the appropriate primary test. CfDNA testing, initially applied to high-risk patients, is now largely considered an option for all patients. For HCPs, the rapid introduction of cfDNA into clinical practice has come with the requirement to stay up-to-date and accurately informed. We performed a survey to understand the current practices and views of European HCPs on the use of cfDNA. European HCPs were surveyed on several topics such as familiarity with cfDNA-based noninvasive prenatal testing (NIPT), current usage, patient counseling, test menu expansion, and future perspectives. The results of this survey demonstrate increasing usage and awareness of cfDNA-based NIPT in five European countries (UK, France, Germany, Spain and Italy). Major barriers to implementation include cost and a lack of physician education on NIPT.

Citace poskytuje Crossref.org

000      
00000naa a2200000 a 4500
001      
bmc20028636
003      
CZ-PrNML
005      
20210114154528.0
007      
ta
008      
210105s2020 ne f 000 0|eng||
009      
AR
024    7_
$a 10.1016/j.ejmg.2019.01.006 $2 doi
035    __
$a (PubMed)30654154
040    __
$a ABA008 $b cze $d ABA008 $e AACR2
041    0_
$a eng
044    __
$a ne
100    1_
$a Benachi, Alexandra $u Service de Gynécologie-Obstétrique. AP-HP, Hôpital Antoine Béclère, Université Paris-Sud, Clamart, France.
245    10
$a Understanding attitudes and behaviors towards cell-free DNA-based noninvasive prenatal testing (NIPT): A survey of European health-care providers / $c A. Benachi, J. Caffrey, P. Calda, E. Carreras, JC. Jani, MD. Kilby, HG. Klein, G. Rizzo, Y. Yaron,
520    9_
$a Cell-free DNA-based noninvasive prenatal testing (cfDNA) is a relatively new screening tool that analyzes cfDNA circulating in maternal plasma to screen for aneuploidies. Since its introduction, cfDNA has been rapidly adopted by health care providers (HCPs). This rapid adoption, as well as progressive developments in the technology, requires professional societies to continuously update their guidelines to indicate the broadening scope both in terms of test indications and patient populations for whom it has become the appropriate primary test. CfDNA testing, initially applied to high-risk patients, is now largely considered an option for all patients. For HCPs, the rapid introduction of cfDNA into clinical practice has come with the requirement to stay up-to-date and accurately informed. We performed a survey to understand the current practices and views of European HCPs on the use of cfDNA. European HCPs were surveyed on several topics such as familiarity with cfDNA-based noninvasive prenatal testing (NIPT), current usage, patient counseling, test menu expansion, and future perspectives. The results of this survey demonstrate increasing usage and awareness of cfDNA-based NIPT in five European countries (UK, France, Germany, Spain and Italy). Major barriers to implementation include cost and a lack of physician education on NIPT.
650    _2
$a aneuploidie $7 D000782
650    _2
$a postoj $7 D001290
650    _2
$a volné cirkulující nukleové kyseliny $x krev $x genetika $7 D000073888
650    _2
$a Downův syndrom $x krev $x genetika $7 D004314
650    _2
$a ženské pohlaví $7 D005260
650    _2
$a zdravotnický personál $x psychologie $7 D006282
650    _2
$a lidé $7 D006801
650    _2
$a neinvazivní prenatální testování $x etika $7 D000081182
650    _2
$a těhotenství $7 D011247
650    _2
$a průzkumy a dotazníky $7 D011795
651    _2
$a Evropa $x epidemiologie $7 D005060
651    _2
$a Francie $x epidemiologie $7 D005602
651    _2
$a Německo $x epidemiologie $7 D005858
651    _2
$a Itálie $x epidemiologie $7 D007558
651    _2
$a Španělsko $x epidemiologie $7 D013030
655    _2
$a časopisecké články $7 D016428
700    1_
$a Caffrey, Jessica $u The Link Group, Australia.
700    1_
$a Calda, Pavel $u Fetal Medicine Center. First Medical Faculty, Charles University and General Teaching Hospital, Prague, Czech Republic.
700    1_
$a Carreras, Elena $u Department of Obstetrics, Hospital Universitari, Vall d'Hebron, Barcelona, Catalonia, Spain.
700    1_
$a Jani, Jacques C $u Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
700    1_
$a Kilby, Mark D $u Centre for Women's & Newborn Health, Institute of Metabolism & Systems Research, University of Birmingham and Fetal Medicine Centre, Birmingham Women's and Children's Foundation Trust, Birmingham, UK.
700    1_
$a Klein, Hanns-Georg $u Center for Human Genetics and Laboratory Diagnostics, Dr. Klein, Dr. Rost & Colleagues, Martinsried, Germany.
700    1_
$a Rizzo, Giuseppe $u Università di Roma Tor Vergata, Department of Maternal ad Fetal Medicine, Ospedale Cristo Re, Rome, Italy; The First I.M. Sechenov Moscow State Medical University, Department of Obstetrics and Gynecology, Moscow, Russia.
700    1_
$a Yaron, Yuval $u Prenatal Genetic Diagnosis Unit, Genetic Institute, Tel Aviv Medical Center, Tel Aviv, Israel. Electronic address: yuvaly@tlvmc.gov.il.
773    0_
$w MED00166495 $t European journal of medical genetics $x 1878-0849 $g Roč. 63, č. 1 (2020), s. 103616
856    41
$u https://pubmed.ncbi.nlm.nih.gov/30654154 $y Pubmed
910    __
$a ABA008 $b sig $c sign $y a $z 0
990    __
$a 20210105 $b ABA008
991    __
$a 20210114154524 $b ABA008
999    __
$a ok $b bmc $g 1608971 $s 1119816
BAS    __
$a 3
BAS    __
$a PreBMC
BMC    __
$a 2020 $b 63 $c 1 $d 103616 $e 20190114 $i 1878-0849 $m European journal of medical genetics $n Eur. J. med. genet. $x MED00166495
LZP    __
$a Pubmed-20210105

Najít záznam

Citační ukazatele

Možnosti archivace