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Breast conservation and axillary management after primary systemic therapy in patients with early-stage breast cancer: the Lucerne toolbox
P. Dubsky, K. Pinker, F. Cardoso, G. Montagna, M. Ritter, C. Denkert, IT. Rubio, E. de Azambuja, G. Curigliano, O. Gentilini, M. Gnant, A. Günthert, N. Hauser, J. Heil, M. Knauer, M. Knotek-Roggenbauerc, S. Knox, T. Kovacs, HM. Kuerer, S. Loibl,...
Jazyk angličtina Země Velká Británie
Typ dokumentu konsensus - konference, časopisecké články, směrnice pro lékařskou praxi, práce podpořená grantem, přehledy
NLK
ProQuest Central
od 2000-09-01 do Před 2 měsíci
Nursing & Allied Health Database (ProQuest)
od 2000-09-01 do Před 2 měsíci
Health & Medicine (ProQuest)
od 2000-09-01 do Před 2 měsíci
Public Health Database (ProQuest)
od 2000-09-01 do Před 2 měsíci
- MeSH
- adjuvantní chemoterapie MeSH
- antitumorózní látky aplikace a dávkování škodlivé účinky MeSH
- delfská metoda MeSH
- klinické rozhodování MeSH
- konsensus MeSH
- lékařská onkologie normy MeSH
- lidé MeSH
- nádory prsu patologie terapie MeSH
- neoadjuvantní terapie škodlivé účinky normy MeSH
- segmentální mastektomie škodlivé účinky normy MeSH
- staging nádorů MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- konsensus - konference MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- směrnice pro lékařskou praxi MeSH
Primary systemic therapy is increasingly used in the treatment of patients with early-stage breast cancer, but few guidelines specifically address optimal locoregional therapies. Therefore, we established an international consortium to discuss clinical evidence and to provide expert advice on technical management of patients with early-stage breast cancer. The steering committee prepared six working packages to address all major clinical questions from diagnosis to surgery. During a consensus meeting that included members from European scientific oncology societies, clinical trial groups, and patient advocates, statements were discussed and voted on. A consensus was reached in 42% of statements, a majority in 38%, and no decision in 21%. Based on these findings, the panel developed clinical guidance recommendations and a toolbox to overcome many clinical and technical requirements associated with the diagnosis, response assessment, surgical planning, and surgery of patients with early-stage breast cancer. This guidance could convince clinicians and patients of the major clinical advancements purported by primary systemic therapy, the use of less extensive and more targeted surgery to improve the lives of patients with breast cancer.
Breast Center Eastern Switzerland St Gallen Switzerland
Breast Center University Hospital Basel Basel Switzerland
Breast Centre Aarau Cham Zug Hirslanden Klinik Aarau Switzerland
Breast Centre Hirslanden Klinik St Anna Luzern Switzerland
Breast Institute Jiahui International Hospital Shanghai China
Breast Service Department of Surgery Memorial Sloan Kettering Cancer Center New York NY USA
Breast Surgery San Raffaele University and Research Hospital Milan Italy
Breast Surgical Oncology Unit Clinica Universidad de Navarra Universidad de Navarra Madrid Spain
Breast Unit Champalimaud Clinical Center and Foundation Lisbon Portugal
Brust Zentrum Zurich Zurich Switzerland
Brustzentrum Bern Biel Bern Switzerland
Centre for Haematology and Oncology Bethanien Frankfurt Germany
Comprehensive Cancer Center Medical University of Vienna Vienna Austria
Department of Breast Surgery Guy's and St Thomas' NHS Foundation Trust London UK
Department of Breast Surgery Gyn zentrum Luzern Luzern Switzerland
Department of Surgery Antoni van Leeuwenhoek Netherlands Cancer Institute Amsterdam Netherlands
Department of Surgery Medical University of Vienna Vienna Austria
Europa Donna The European Breast Cancer Coalition Milan Italy
Faculty of Medicine and Health Sciences University of Antwerp Wilrijk Antwerp Belgium
Faculty of Medicine University of Basel Basel Switzerland
Frauenarztzentrum Aargau Ag Baden Switzerland
German Breast Group Neu Isenburg Germany
Heidelberg University Hospital Heidelberg Germany
Institut Jules Bordet Brussels Belgium
Institute of Pathology Philipps University Marburg and University Hospital Marburg Marburg Germany
Iridium Kankernetwerk Wilrijk Antwerp Belgium
Istituto Europeo di Oncologia IRCCS and University of Milano Milan Italy
l'Université Libre de Bruxelles Brussels Belgium
Nova Medical School Lisbon Portugal
Radiation Oncology Unit Oncology Department Azienda Ospedaliero Universitaria Careggi Florence Italy
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- $a Dubsky, Peter $u Breast Centre, Hirslanden Klinik St Anna, Luzern, Switzerland; Department of Surgery, Medical University of Vienna, Vienna, Austria; Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria. Electronic address: leitung-brustzentrum.stanna@hirslanden.ch
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- $a Breast conservation and axillary management after primary systemic therapy in patients with early-stage breast cancer: the Lucerne toolbox / $c P. Dubsky, K. Pinker, F. Cardoso, G. Montagna, M. Ritter, C. Denkert, IT. Rubio, E. de Azambuja, G. Curigliano, O. Gentilini, M. Gnant, A. Günthert, N. Hauser, J. Heil, M. Knauer, M. Knotek-Roggenbauerc, S. Knox, T. Kovacs, HM. Kuerer, S. Loibl, M. Mannhart, I. Meattini, F. Penault-Llorca, N. Radosevic-Robin, P. Sager, T. Španić, P. Steyerova, C. Tausch, MTFDV. Peeters, WP. Weber, MJ. Cardoso, P. Poortmans
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- $a Primary systemic therapy is increasingly used in the treatment of patients with early-stage breast cancer, but few guidelines specifically address optimal locoregional therapies. Therefore, we established an international consortium to discuss clinical evidence and to provide expert advice on technical management of patients with early-stage breast cancer. The steering committee prepared six working packages to address all major clinical questions from diagnosis to surgery. During a consensus meeting that included members from European scientific oncology societies, clinical trial groups, and patient advocates, statements were discussed and voted on. A consensus was reached in 42% of statements, a majority in 38%, and no decision in 21%. Based on these findings, the panel developed clinical guidance recommendations and a toolbox to overcome many clinical and technical requirements associated with the diagnosis, response assessment, surgical planning, and surgery of patients with early-stage breast cancer. This guidance could convince clinicians and patients of the major clinical advancements purported by primary systemic therapy, the use of less extensive and more targeted surgery to improve the lives of patients with breast cancer.
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- $a Pinker, Katja $u Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria; Breast Imaging Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
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- $a Curigliano, Giuseppe $u Istituto Europeo di Oncologia, IRCCS and University of Milano, Milan, Italy
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