-
Je něco špatně v tomto záznamu ?
Sex and age as determinants for high blood pressure in pediatric renal transplant recipients: a longitudinal analysis of the CERTAIN Registry
RI. Sugianto, BMW. Schmidt, N. Memaran, A. Duzova, R. Topaloglu, T. Seeman, S. König, L. Dello Strologo, L. Murer, ZB. Özçakar, M. Bald, M. Shenoy, A. Buescher, PF. Hoyer, M. Pohl, H. Billing, J. Oh, H. Staude, M. Pohl, G. Genc, G. Klaus, C....
Jazyk angličtina Země Německo
Typ dokumentu časopisecké články, práce podpořená grantem
NLK
ProQuest Central
od 1996-08-01 do Před 1 rokem
Medline Complete (EBSCOhost)
od 1996-08-01 do Před 1 rokem
Nursing & Allied Health Database (ProQuest)
od 1996-08-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 1996-08-01 do Před 1 rokem
Family Health Database (ProQuest)
od 1996-08-01 do Před 1 rokem
- MeSH
- časové faktory MeSH
- cyklosporin aplikace a dávkování škodlivé účinky farmakokinetika MeSH
- dítě MeSH
- hypertenze diagnóza epidemiologie etiologie MeSH
- imunosupresiva aplikace a dávkování škodlivé účinky farmakokinetika MeSH
- lidé MeSH
- longitudinální studie MeSH
- měření krevního tlaku statistika a číselné údaje MeSH
- mladiství MeSH
- následné studie MeSH
- předškolní dítě MeSH
- prevalence MeSH
- příjemce transplantátu statistika a číselné údaje MeSH
- registrace statistika a číselné údaje MeSH
- rejekce štěpu imunologie prevence a kontrola MeSH
- retrospektivní studie MeSH
- sexuální faktory MeSH
- takrolimus aplikace a dávkování škodlivé účinky farmakokinetika MeSH
- transplantace ledvin škodlivé účinky MeSH
- věkové faktory MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- předškolní dítě MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Evropa MeSH
BACKGROUND: High prevalence of arterial hypertension is known in pediatric renal transplant patients, but how blood pressure (BP) distribution and control differ between age groups and whether sex and age interact and potentially impact BP after transplantation have not been investigated. METHODS: This retrospective analysis included 336 pediatric renal transplant recipients (62% males) from the Cooperative European Pediatric Renal Transplant Initiative Registry (CERTAIN) with complete BP measurement at discharge and 1, 2 and 3 years post-transplant. RESULTS: At discharge and 3 years post-transplant, arterial hypertension was highly prevalent (84% and 77%); antihypertensive drugs were used in 73% and 68% of the patients. 27% suffered from uncontrolled and 9% from untreated hypertension at 3 years post-transplant. Children transplanted at age < 5 years showed sustained high systolic BP z-score and received consistently less antihypertensive treatment over time. Younger age, shorter time since transplantation, male sex, higher body mass index (BMI), high cyclosporine A (CSA) trough levels, and a primary renal disease other than congenital anomalies of the kidney and urinary tract (CAKUT) were significantly associated with higher systolic BP z-score. Sex-stratified analysis revealed a significant association between high CSA and higher systolic BP in older girls that likely had started puberty already. An association between BP and estimated glomerular filtration rate was not detected. CONCLUSIONS: BP control during the first 3 years was poor in this large European cohort. The description of age- and sex-specific risk profiles identified certain recipient groups that may benefit from more frequent BP monitoring (i.e. young children) or different choices of immunosuppression (i.e. older girls).
Center for Children and Adolescent Pediatric Clinic 2 University of Duisburg Essen Essen Germany
Department of General Pediatrics University Hospital Muenster Muenster Germany
Department of General Pediatrics University of Tuebingen Tuebingen Germany
Department of Nephrology Hannover Medical School Hannover Germany
Department of Pediatric Nephrology Izmir Tepecik Teaching and Research Hospital Izmir Turkey
Department of Pediatrics 1 University Children's Hospital Heidelberg Heidelberg Germany
Department of Pediatrics 2nd Faculty of Medicine Charles University Prague Czech Republic
Division of Pediatric Nephrology Faculty of Medicine Ankara University Ankara Turkey
Division of Pediatric Nephrology Faculty of Medicine Hacettepe University Ankara Turkey
Division of Pediatric Nephrology Faculty of Medicine Ondokuz Mayis University Samsun Turkey
KfH Kidney Centre for Children and Adolescents St Georg Hospital Leipzig Germany
KfH Kidney Centre for Children and Adolescents University Hospital Giessen Marburg Marburg Germany
Olga Children's Hospital Clinic of Stuttgart Stuttgart Germany
Pediatric Nephrology Dialysis and Transplant Unit Hospital University Padua Padua Italy
Renal Transplant Clinic Bambino Gesu Children's Hospital IRCCS Rome Italy
Royal Manchester Hospital Manchester UK
Citace poskytuje Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc21012841
- 003
- CZ-PrNML
- 005
- 20210507104127.0
- 007
- ta
- 008
- 210420s2020 gw f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1007/s00467-019-04395-4 $2 doi
- 035 __
- $a (PubMed)31811541
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a gw
- 100 1_
- $a Sugianto, Rizky I $u Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
- 245 10
- $a Sex and age as determinants for high blood pressure in pediatric renal transplant recipients: a longitudinal analysis of the CERTAIN Registry / $c RI. Sugianto, BMW. Schmidt, N. Memaran, A. Duzova, R. Topaloglu, T. Seeman, S. König, L. Dello Strologo, L. Murer, ZB. Özçakar, M. Bald, M. Shenoy, A. Buescher, PF. Hoyer, M. Pohl, H. Billing, J. Oh, H. Staude, M. Pohl, G. Genc, G. Klaus, C. Alparslan, R. Grenda, J. Rubik, K. Krupka, B. Tönshoff, E. Wühl, A. Melk
- 520 9_
- $a BACKGROUND: High prevalence of arterial hypertension is known in pediatric renal transplant patients, but how blood pressure (BP) distribution and control differ between age groups and whether sex and age interact and potentially impact BP after transplantation have not been investigated. METHODS: This retrospective analysis included 336 pediatric renal transplant recipients (62% males) from the Cooperative European Pediatric Renal Transplant Initiative Registry (CERTAIN) with complete BP measurement at discharge and 1, 2 and 3 years post-transplant. RESULTS: At discharge and 3 years post-transplant, arterial hypertension was highly prevalent (84% and 77%); antihypertensive drugs were used in 73% and 68% of the patients. 27% suffered from uncontrolled and 9% from untreated hypertension at 3 years post-transplant. Children transplanted at age < 5 years showed sustained high systolic BP z-score and received consistently less antihypertensive treatment over time. Younger age, shorter time since transplantation, male sex, higher body mass index (BMI), high cyclosporine A (CSA) trough levels, and a primary renal disease other than congenital anomalies of the kidney and urinary tract (CAKUT) were significantly associated with higher systolic BP z-score. Sex-stratified analysis revealed a significant association between high CSA and higher systolic BP in older girls that likely had started puberty already. An association between BP and estimated glomerular filtration rate was not detected. CONCLUSIONS: BP control during the first 3 years was poor in this large European cohort. The description of age- and sex-specific risk profiles identified certain recipient groups that may benefit from more frequent BP monitoring (i.e. young children) or different choices of immunosuppression (i.e. older girls).
- 650 _2
- $a mladiství $7 D000293
- 650 _2
- $a věkové faktory $7 D000367
- 650 _2
- $a měření krevního tlaku $x statistika a číselné údaje $7 D001795
- 650 _2
- $a dítě $7 D002648
- 650 _2
- $a předškolní dítě $7 D002675
- 650 _2
- $a cyklosporin $x aplikace a dávkování $x škodlivé účinky $x farmakokinetika $7 D016572
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 _2
- $a následné studie $7 D005500
- 650 _2
- $a rejekce štěpu $x imunologie $x prevence a kontrola $7 D006084
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a hypertenze $x diagnóza $x epidemiologie $x etiologie $7 D006973
- 650 _2
- $a imunosupresiva $x aplikace a dávkování $x škodlivé účinky $x farmakokinetika $7 D007166
- 650 _2
- $a transplantace ledvin $x škodlivé účinky $7 D016030
- 650 _2
- $a longitudinální studie $7 D008137
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a prevalence $7 D015995
- 650 _2
- $a registrace $x statistika a číselné údaje $7 D012042
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a sexuální faktory $7 D012737
- 650 _2
- $a takrolimus $x aplikace a dávkování $x škodlivé účinky $x farmakokinetika $7 D016559
- 650 _2
- $a časové faktory $7 D013997
- 650 _2
- $a příjemce transplantátu $x statistika a číselné údaje $7 D066027
- 651 _2
- $a Evropa $x epidemiologie $7 D005060
- 655 _2
- $a časopisecké články $7 D016428
- 655 _2
- $a práce podpořená grantem $7 D013485
- 700 1_
- $a Schmidt, Bernhard M W $u Department of Nephrology, Hannover Medical School, Hannover, Germany
- 700 1_
- $a Memaran, Nima $u Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany
- 700 1_
- $a Duzova, Ali $u Division of Pediatric Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
- 700 1_
- $a Topaloglu, Rezan $u Division of Pediatric Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
- 700 1_
- $a Seeman, Tomas $u Department of Pediatrics, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic
- 700 1_
- $a König, Sabine $u Department of General Pediatrics, University Hospital Muenster, Muenster, Germany
- 700 1_
- $a Dello Strologo, Luca $u Renal Transplant Clinic, Bambino Gesu Children's Hospital IRCCS, Rome, Italy
- 700 1_
- $a Murer, Luisa $u Pediatric Nephrology, Dialysis and Transplant Unit, Hospital University Padua, Padua, Italy
- 700 1_
- $a Özçakar, Zeynep Birsin $u Division of Pediatric Nephrology, Faculty of Medicine, Ankara University, Ankara, Turkey
- 700 1_
- $a Bald, Martin $u Olga Children's Hospital, Clinic of Stuttgart, Stuttgart, Germany
- 700 1_
- $a Shenoy, Mohan $u Royal Manchester Hospital, Manchester, UK
- 700 1_
- $a Buescher, Anja $u Center for Children and Adolescent, Pediatric Clinic II, University of Duisburg-Essen, Essen, Germany
- 700 1_
- $a Hoyer, Peter F $u Center for Children and Adolescent, Pediatric Clinic II, University of Duisburg-Essen, Essen, Germany
- 700 1_
- $a Pohl, Michael $u KfH Kidney Centre for Children and Adolescents, St. Georg Hospital, Leipzig, Germany
- 700 1_
- $a Billing, Heiko $u Department of General Pediatrics, University of Tuebingen, Tuebingen, Germany
- 700 1_
- $a Oh, Jun $u Division of Pediatric Nephrology and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
- 700 1_
- $a Staude, Hagen $u University Children's Hospital Rostock, Rostock, Germany
- 700 1_
- $a Pohl, Martin $u Department of General Pediatrics, Adolescent Medicine and Neonatology, Faculty of Medicine, University of Freiburg, Freiburg, Germany
- 700 1_
- $a Genc, Gurkan $u Division of Pediatric Nephrology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey
- 700 1_
- $a Klaus, Günter $u KfH Kidney Centre for Children and Adolescents, University Hospital Giessen-Marburg, Marburg, Germany
- 700 1_
- $a Alparslan, Caner $u Department of Pediatric Nephrology, Izmir Tepecik Teaching and Research Hospital, Izmir, Turkey
- 700 1_
- $a Grenda, Ryszard $u The Children's Memorial Health Institute, Warsaw, Poland
- 700 1_
- $a Rubik, Jacek $u The Children's Memorial Health Institute, Warsaw, Poland
- 700 1_
- $a Krupka, Kai $u Department of Pediatrics I, University Children's Hospital Heidelberg, Heidelberg, Germany
- 700 1_
- $a Tönshoff, Burkhard $u Department of Pediatrics I, University Children's Hospital Heidelberg, Heidelberg, Germany
- 700 1_
- $a Wühl, Elke $u Department of Pediatrics I, University Children's Hospital Heidelberg, Heidelberg, Germany
- 700 1_
- $a Melk, Anette $u Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Melk.Anette@mh-hannover.de
- 773 0_
- $w MED00003733 $t Pediatric nephrology (Berlin, Germany) $x 1432-198X $g Roč. 35, č. 3 (2020), s. 415-426
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/31811541 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y p $z 0
- 990 __
- $a 20210420 $b ABA008
- 991 __
- $a 20210507104125 $b ABA008
- 999 __
- $a ok $b bmc $g 1651085 $s 1133220
- BAS __
- $a 3
- BAS __
- $a PreBMC
- BMC __
- $a 2020 $b 35 $c 3 $d 415-426 $e 20191207 $i 1432-198X $m Pediatric nephrology $n Pediatr Nephrol $x MED00003733
- LZP __
- $a Pubmed-20210420
