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Should posterior cerebral artery occlusions be recanalized? Insights from the Trevo Registry
F. Clarençon, F. Baronnet, E. Shotar, V. Degos, C. Rolla-Bigliani, B. Bartolini, E. Veznedaroglu, R. Budzik, J. English, B. Baxter, DS. Liebeskind, A. Krajina, R. Gupta, S. Miralbes, A. Lüttich, RG. Nogueira, Y. Samson, S. Alamowitch, NA. Sourour
Jazyk angličtina Země Velká Británie
Typ dokumentu časopisecké články, multicentrická studie
Grantová podpora
NCT02040259
Stryker - International
PubMed
31997505
DOI
10.1111/ene.14154
Knihovny.cz E-zdroje
- MeSH
- arteria cerebri posterior patologie MeSH
- arteriální okluzní nemoci komplikace patologie terapie MeSH
- cévní mozková příhoda komplikace terapie MeSH
- dospělí MeSH
- internacionalita * MeSH
- ischemie mozku komplikace terapie MeSH
- katetrizace metody MeSH
- lidé středního věku MeSH
- lidé MeSH
- registrace * MeSH
- retrospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- stenty MeSH
- tkáňový aktivátor plazminogenu terapeutické užití MeSH
- trombektomie MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
BACKGROUND AND PURPOSE: The purpose of this study was to evaluate the safety and effectiveness of mechanical thrombectomy (MT) in patients with acute ischaemic stroke related to isolated and primary posterior cerebral artery (PCA) occlusions amongst the patients enrolled in the multicentre post-market Trevo Registry. METHOD: Amongst the 2008 patients enrolled in the Trevo Registry with acute ischaemic stroke due to large vessel occlusion treated by MT, 22 patients (1.1%) [10 females (45.5%), mean age 66.2 ± 14.3 years (range 28-91)] had a PCA occlusion [17 P1 (77.3%) and five P2 occlusions (22.7%)]. Recanalization after the first Trevo (Stryker, Fremont, CA, USA) pass and at the end of the procedure was rated using the modified Thrombolysis in Cerebral Infarction (mTICI) score. Procedure-related complications (i.e. groin puncture complication, perforation, symptomatic haemorrhage, embolus in a new territory) were also recorded. The modified Rankin Scale at 90 days was assessed. RESULTS: Median National Institutes of Health Stroke Scale at admission was 14 (interquartile range 8-16). Stroke aetiology was cardio-embolic in 68.2% of cases. Half of the patients (11/22) received intravenous tissue plasminogen activator. 54.5% of the patients were treated under general anaesthesia. Reperfusion (i.e. mTICI 2b or 3) after first pass was obtained in 65% of cases. Final mTICI 2b-3 reperfusion was obtained in all cases. Only one (4.5%) procedure-related complication was recorded (puncture site) that resolved after surgery. At 90-day follow-up, modified Rankin Scale 0-2 was obtained in 59% of the patients and 9.1% died within the first 3 months after MT. CONCLUSION: Mechanical thrombectomy for PCA occlusions seems to be safe (<5% procedure-related complications) and effective. Larger repository datasets are needed.
Department of Anesthesiology Pitié Salpêtrière Hospital Paris France
Department of Neuroradiology Pitié Salpêtrière Hospital Paris France
Department of Radiology University Hospital Hradec Kralove Hradec Kralove Czech Republic
Department of Vascular Neurology Pitié Salpêtrière Hospital Paris France
Department of Vascular Neurology Saint Antoine University Hospital Paris France
Endovascular Neurosurgery Drexel Neurosciences Institute Philadelphia PA USA
Hospital de Donostia San Sebastian España
Hospital Universitario Son Espases Mallorca España
Interventional Neurology California Pacific Medical Center San Francisco CA USA
Interventional Neurology Wellstar Health System Atlanta GA USA
Citace poskytuje Crossref.org
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